iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115665

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

S-phase kinase-associated protein 2

Genbank Nucleotide ID

CU856110

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000016835.2	ENSSSCT00000018330.2	ENSSSCP00000017834.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	28.40	1.00e-30	130.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	94.34	0.00e+00	821.00	IUUC-Hsa-046512
E3 adaptor/Cullin RING/SCF/F-box	56.70	4.00e-126	449.00	IUUC-Ots-000025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MHRKHLQEIP DQSSNVTTSF TWGWDSSKTS ELLSGMGVSA LEKEEVDSEN IPQELLSNLG 60
HPQSPPRKRL KSKGNEKDFV IVRRPKLNRE NFPGVSWDSL PDELLLGIFS CLCLPELLKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCGCAGAC GGTAGCGGGG AGGAGAGCGG GCAGAAGTTT TCTGCGCGCG CGGTGGGGAT 60
GGAACGTTGA TAGAGTTCGC GGGTCTCACT GCTGGGGGCT GGAGCCACAC GCAGTGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016301--F:kinase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ssc:100329128

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	96.23	0.00e+00	808.00
IUUC-Atr-002711	Amborella trichopoda	25.00	4.00e-10	60.50
IUUC-Apl-003453	Anas platyrhynchos	68.77	6.00e-122	429.00
IUUC-Aca-005185	Anolis carolinensis	62.91	2.00e-144	505.00
IUUC-Ame-010665	Astyanax mexicanus	47.12	9.00e-92	330.00
IUUC-Bta-013450	Bos taurus	95.75	0.00e+00	836.00
IUUC-Bra-016626	Brassica rapa	23.53	5.00e-11	63.20
IUUC-Cel-018410	Caenorhabditis elegans	27.78	8.00e-28	117.00
IUUC-Cja-019834	Callithrix jacchus	92.92	0.00e+00	809.00
IUUC-Cfa-020401	Canis familiaris	96.93	0.00e+00	841.00
IUUC-Cpo-022183	Cavia porcellus	91.98	0.00e+00	806.00
IUUC-Csa-023418	Chlorocebus sabaeus	94.58	0.00e+00	820.00
IUUC-Cho-024412	Choloepus hoffmanni	89.27	0.00e+00	638.00
IUUC-Cin-025248	Ciona intestinalis	31.40	6.00e-40	157.00
IUUC-Csv-026189	Ciona savignyi	33.33	5.00e-36	145.00
IUUC-Cme-027297	Cyanidioschyzon merolae	34.29	1.00e-05	44.30
IUUC-Dre-028032	Danio rerio	48.00	4.00e-104	370.00
IUUC-Dno-029222	Dasypus novemcinctus	93.63	0.00e+00	814.00
IUUC-Dor-030505	Dipodomys ordii	87.01	1.00e-175	608.00
IUUC-Dme-031972	Drosophila melanogaster	32.88	1.00e-51	197.00
IUUC-Ete-032234	Echinops telfairi	83.70	4.00e-118	417.00
IUUC-Eca-033944	Equus caballus	97.17	0.00e+00	846.00
IUUC-Eeu-035008	Erinaceus europaeus	77.23	1.00e-123	436.00
IUUC-Fca-035412	Felis catus	95.52	0.00e+00	831.00
IUUC-Fal-037337	Ficedula albicollis	64.45	1.00e-141	496.00
IUUC-Gmo-038934	Gadus morhua	43.31	1.00e-41	163.00
IUUC-Gga-041152	Gallus gallus	67.54	1.00e-161	562.00
IUUC-Gac-041819	Gasterosteus aculeatus	45.05	7.00e-78	283.00
IUUC-Ggo-045479	Gorilla gorilla	92.94	0.00e+00	677.00
IUUC-Hsa-046512	Homo sapiens	94.34	0.00e+00	821.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	93.12	0.00e+00	774.00
IUUC-Lch-050115	Latimeria chalumnae	58.95	4.00e-139	487.00
IUUC-Loc-052554	Lepisosteus oculatus	50.00	9.00e-109	386.00
IUUC-Laf-053563	Loxodonta africana	92.89	0.00e+00	766.00
IUUC-Mcc-055143	Macaca mulatta	94.55	0.00e+00	815.00
IUUC-Meu-056593	Macropus eugenii	57.77	1.00e-108	386.00
IUUC-Mga-060084	Meleagris gallopavo	59.39	1.00e-84	305.00
IUUC-Mmr-060660	Microcebus murinus	98.11	0.00e+00	852.00
IUUC-Mdo-062363	Monodelphis domestica	70.05	9.00e-163	565.00
IUUC-Mmu-063287	Mus musculus	85.85	0.00e+00	756.00
IUUC-Mpu-065791	Mustela putorius furo	96.46	0.00e+00	839.00
IUUC-Mlu-067714	Myotis lucifugus	90.59	0.00e+00	775.00
IUUC-Nle-069823	Nomascus leucogenys	94.81	0.00e+00	823.00
IUUC-Opr-071046	Ochotona princeps	75.00	7.00e-108	383.00
IUUC-Ont-071820	Oreochromis niloticus	46.61	1.00e-70	259.00
IUUC-Ocu-074868	Oryctolagus cuniculus	94.34	0.00e+00	818.00
IUUC-Ola-086608	Oryzias latipes	46.61	2.00e-76	278.00
IUUC-Oga-089044	Otolemur garnettii	95.28	0.00e+00	831.00
IUUC-Oar-089650	Ovis aries	95.75	0.00e+00	832.00
IUUC-Ptr-090743	Pan troglodytes	94.34	0.00e+00	820.00
IUUC-Pan-092501	Papio anubis	94.58	0.00e+00	820.00
IUUC-Psi-094032	Pelodiscus sinensis	67.77	2.00e-165	574.00
IUUC-Pfo-097279	Poecilia formosa	46.27	1.00e-65	243.00
IUUC-Pab-097821	Pongo abelii	93.79	0.00e+00	680.00
IUUC-Pca-100100	Procavia capensis	91.53	0.00e+00	628.00
IUUC-Pva-103181	Pteropus vampyrus	93.79	0.00e+00	657.00
IUUC-Rno-105091	Rattus norvegicus	87.68	0.00e+00	765.00
IUUC-Sha-107226	Sarcophilus harrisii	72.04	3.00e-173	600.00
IUUC-Smo-109321	Selaginella moellendorffii	23.86	7.00e-12	66.20
IUUC-Tgu-116982	Taeniopygia guttata	64.07	8.00e-139	486.00
IUUC-Tru-118276	Takifugu rubripes	46.25	2.00e-75	276.00
IUUC-Tsy-119074	Tarsius syrichta	93.50	0.00e+00	677.00
IUUC-Tni-120702	Tetraodon nigroviridis	47.20	6.00e-52	197.00
IUUC-Tbe-127990	Tupaia belangeri	93.96	5.00e-164	570.00
IUUC-Ttr-128661	Tursiops truncatus	82.69	9.00e-120	423.00
IUUC-Vvi-131526	Vitis vinifera	25.75	1.00e-10	61.60
IUUC-Xtr-132166	Xenopus tropicalis	56.94	3.00e-128	451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence