iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116956

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01037862

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008834.1	ENSTGUT00000009210.1	ENSTGUP00000009112.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.30e-89	298.5	3	612

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 76   alkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclec 159
           +++++a++f+gy+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++c+ c
   Q: 3    IVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRPDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLVCPMC 89
           5778999************************************9999..6666666777****************************** PP
   S: 160  dnvssreepfldlslpvpgkeetkke............................................................... 185
            +vs +++pfl+l++p+p+k++  +                                                                
   Q: 90   SKVSITFDPFLYLPVPLPQKQKVLTVyyfakephkkpikvkdastlgrepekapggapgscscanrlsrvlskgphalgvtnvtlswwq 178
           *********************87555*************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 179  flvsiskenssamevldscsfpgcsraefsrvyvcyracqkthwpdhkascrpenigfpflisvpesrltyarlaqllegyarysvsvf 267
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 268  qppfqlgrmspeqglqplhsdkleplakssygdrvsslpqepplspavpelqpemgdtttvrskvltarssllsldsgslstwsrrvta 356
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 357  vpsyeralkpeaaipgyqhtpdslsaratqfyitkidsanrehkledkgdttldltddcsllvwknnerlkefvlveskelecvedpgs 445
           ***************************************************************************************** PP
   S: 186  ..........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlsp 263
                     +l++cL+ ftk+e l  e+++yc+kck+++ea+k+l+l++lP+vLi++LkRfsf++  +++ kin+ v+fp + Ldls+
   Q: 446  aseaaraghfTLEQCLNLFTKPEVLAPEEAWYCPKCKQHREASKQLMLWRLPNVLIIQLKRFSFRSFIWRD-KINDMVDFPVRsLDLSK 533
           *******************************************************************8886.***************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           fc+ ++ +q +   Y+L+av++H+G++ +GHY+ay++  ++k        W lfdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 534  FCIGRKGEQ-QLPVYDLYAVINHYGGMIGGHYTAYARLPNDKnsqrsdvgWRLFDDSTVTTVDESQVVT---RYAYVLFYRRR 612
           ****88777.5**************************9554455677888*******************...********996 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

QAIVASKASQ FTGYAQHDAQ EFMAFLLDGL HEDLNRIQNK PYTETVDSDG RPDEVVAEEA 60
WQRHKMRNDS FIVDLFQGQY KSKLVCPMCS KVSITFDPFL YLPVPLPQKQ KVLTVYYFAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCAATTG TGGCCAGCAA GGCCAGCCAG TTCACTGGCT ATGCCCAGCA TGATGCTCAG 60
GAATTTATGG CCTTTCTGCT TGATGGCCTG CATGAGGACC TCAACCGCAT CCAGAACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	63.34	0.00e+00	816.00
IUUC-Apl-003368	Anas platyrhynchos	76.86	0.00e+00	990.00
IUUC-Aca-004267	Anolis carolinensis	69.93	0.00e+00	899.00
IUUC-Ame-010970	Astyanax mexicanus	61.62	0.00e+00	742.00
IUUC-Bta-012905	Bos taurus	64.52	0.00e+00	814.00
IUUC-Cja-018789	Callithrix jacchus	64.02	0.00e+00	853.00
IUUC-Cfa-021004	Canis familiaris	64.23	0.00e+00	814.00
IUUC-Cpo-021529	Cavia porcellus	62.04	0.00e+00	834.00
IUUC-Csa-024035	Chlorocebus sabaeus	65.13	0.00e+00	819.00
IUUC-Cho-025036	Choloepus hoffmanni	68.99	8.00e-125	441.00
IUUC-Cin-025451	Ciona intestinalis	47.47	3.00e-56	213.00
IUUC-Csv-025931	Ciona savignyi	45.12	2.00e-53	202.00
IUUC-Dre-028556	Danio rerio	62.28	0.00e+00	741.00
IUUC-Dno-029240	Dasypus novemcinctus	60.98	0.00e+00	781.00
IUUC-Dor-030495	Dipodomys ordii	61.30	0.00e+00	740.00
IUUC-Ete-032741	Echinops telfairi	63.46	0.00e+00	787.00
IUUC-Eca-033661	Equus caballus	63.67	0.00e+00	850.00
IUUC-Eeu-034648	Erinaceus europaeus	82.10	4.00e-114	405.00
IUUC-Fca-035646	Felis catus	64.97	0.00e+00	818.00
IUUC-Fal-037094	Ficedula albicollis	80.85	0.00e+00	1142.00
IUUC-Gmo-038869	Gadus morhua	77.19	1.00e-120	427.00
IUUC-Gga-041170	Gallus gallus	78.78	0.00e+00	1076.00
IUUC-Gac-041901	Gasterosteus aculeatus	57.35	0.00e+00	728.00
IUUC-Ggo-044708	Gorilla gorilla	63.99	0.00e+00	868.00
IUUC-Hsa-046791	Homo sapiens	64.51	0.00e+00	853.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	61.56	0.00e+00	853.00
IUUC-Lch-050456	Latimeria chalumnae	60.18	2.00e-172	599.00
IUUC-Loc-052861	Lepisosteus oculatus	48.87	5.00e-151	528.00
IUUC-Laf-053788	Loxodonta africana	61.78	0.00e+00	854.00
IUUC-Mcc-055693	Macaca mulatta	65.13	0.00e+00	821.00
IUUC-Meu-055921	Macropus eugenii	63.94	0.00e+00	667.00
IUUC-Mga-059879	Meleagris gallopavo	77.08	0.00e+00	1075.00
IUUC-Mmr-060802	Microcebus murinus	61.55	0.00e+00	853.00
IUUC-Mdo-061856	Monodelphis domestica	65.01	0.00e+00	883.00
IUUC-Mmu-063874	Mus musculus	61.68	0.00e+00	844.00
IUUC-Mpu-066166	Mustela putorius furo	64.38	0.00e+00	813.00
IUUC-Nle-070161	Nomascus leucogenys	63.76	0.00e+00	848.00
IUUC-Opr-071015	Ochotona princeps	64.68	0.00e+00	810.00
IUUC-Ont-072308	Oreochromis niloticus	61.73	0.00e+00	777.00
IUUC-Oan-072723	Ornithorhynchus anatinus	62.52	0.00e+00	886.00
IUUC-Ocu-073938	Oryctolagus cuniculus	63.93	0.00e+00	807.00
IUUC-Ola-086375	Oryzias latipes	63.10	0.00e+00	782.00
IUUC-Oga-088297	Otolemur garnettii	62.18	0.00e+00	844.00
IUUC-Oar-089675	Ovis aries	62.23	0.00e+00	704.00
IUUC-Ptr-091621	Pan troglodytes	63.94	0.00e+00	850.00
IUUC-Pan-092118	Papio anubis	65.13	0.00e+00	819.00
IUUC-Pma-094169	Petromyzon marinus	55.65	7.00e-64	237.00
IUUC-Pfo-097246	Poecilia formosa	60.85	0.00e+00	744.00
IUUC-Pab-098551	Pongo abelii	63.10	0.00e+00	834.00
IUUC-Pca-100158	Procavia capensis	61.87	0.00e+00	842.00
IUUC-Pva-103160	Pteropus vampyrus	63.46	0.00e+00	840.00
IUUC-Rno-105355	Rattus norvegicus	63.98	0.00e+00	843.00
IUUC-Sha-107057	Sarcophilus harrisii	67.21	0.00e+00	841.00
IUUC-Sar-113011	Sorex araneus	53.74	2.00e-118	420.00
IUUC-Ssc-115761	Sus scrofa	64.74	0.00e+00	817.00
IUUC-Tru-118739	Takifugu rubripes	61.18	0.00e+00	765.00
IUUC-Tsy-118827	Tarsius syrichta	70.20	2.00e-72	267.00
IUUC-Tni-119921	Tetraodon nigroviridis	60.33	0.00e+00	749.00
IUUC-Tbe-128017	Tupaia belangeri	62.42	0.00e+00	835.00
IUUC-Ttr-128869	Tursiops truncatus	63.01	0.00e+00	860.00
IUUC-Vpa-130427	Vicugna pacos	54.97	8.00e-130	457.00
IUUC-Xtr-132734	Xenopus tropicalis	64.95	0.00e+00	816.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence