iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117229

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01047117

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000006001.1	ENSTGUT00000006255.1	ENSTGUP00000006194.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	3.70e-06	26.9	814	903
E3 activity/RING/PHD	6.90e-15	54.8	605	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 55   srrtprqpprgpsaaakpkaglrseaaaapap.apaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkal 142
            r tpr   r p + + pk+         p p +p p   p    d g  + ++ e+++ ++++l++++l+ + rvc++w++ + +k+l
   Q: 814  LRSTPRGIARPPPSLSPPKCIQMERHVIRPPPiSPPPDSLPL---DDGAAHVMQREVWMAVFSYLSHRDLCICMRVCKTWNRWCCDKRL 899
           5889******99999999986666566666551344444443...6677788889**************************5555599* PP
   S: 143  wktv 146
           w ++
   Q: 900  WTKI 903
           9986 PP

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++      +l+eC++C+e++Hp+Clk +     v++elpn+  w+CpkC+++
   Q: 605  AVCLVCGEAGKEDTskfnlMLMECSICNEIIHPGCLKVKesdgvVNDELPNC--WECPKCNHA 665
           79*********99667889*********************************..*******85 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

RRRYDENEDL SDVEEIVSIR SFNLEEKLKS KMYHGDFVHA MDGKDFTFEY VQREALRVPL 60
IFRNKDGLGI KMPDPDFTVR DVKLLVGDRR IVDVMDVNTQ RGVEMSMSQF VRYYETPEAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAAGGCGGT ACGATGAGAA CGAGGACCTC TCGGACGTGG AGGAAATTGT CAGCATCAGG 60
AGTTTCAATT TGGAAGAGAA ATTAAAGAGT AAAATGTACC ACGGGGATTT CGTGCATGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	73.70	0.00e+00	1075.00
IUUC-Apl-003787	Anas platyrhynchos	81.91	0.00e+00	1843.00
IUUC-Acl-008303	Aspergillus clavatus	44.70	2.00e-63	237.00
IUUC-Afu-008903	Aspergillus fumigatus	44.70	1.00e-63	238.00
IUUC-Ani-009279	Aspergillus nidulans	45.82	4.00e-63	236.00
IUUC-Aor-010233	Aspergillus oryzae	45.45	2.00e-63	237.00
IUUC-Ate-010345	Aspergillus terreus	45.08	6.00e-65	243.00
IUUC-Bta-013531	Bos taurus	74.19	0.00e+00	1098.00
IUUC-Cel-018303	Caenorhabditis elegans	45.48	1.00e-83	305.00
IUUC-Cme-027118	Cyanidioschyzon merolae	32.95	2.00e-49	190.00
IUUC-Dre-028272	Danio rerio	65.83	0.00e+00	919.00
IUUC-Dor-030736	Dipodomys ordii	87.25	0.00e+00	646.00
IUUC-Dse-031402	Dothistroma septosporum	42.11	3.00e-60	227.00
IUUC-Fal-037589	Ficedula albicollis	84.74	0.00e+00	1976.00
IUUC-Gga-041103	Gallus gallus	88.02	0.00e+00	1142.00
IUUC-Ggo-044522	Gorilla gorilla	88.08	0.00e+00	652.00
IUUC-Lch-049950	Latimeria chalumnae	72.57	0.00e+00	1070.00
IUUC-Loc-051972	Lepisosteus oculatus	72.06	0.00e+00	985.00
IUUC-Lma-053190	Leptosphaeria maculans	42.01	2.00e-60	228.00
IUUC-Meu-056259	Macropus eugenii	72.70	0.00e+00	1068.00
IUUC-Mlu-067850	Myotis lucifugus	73.27	0.00e+00	1062.00
IUUC-Nfi-068537	Neosartorya fischeri	44.70	2.00e-63	238.00
IUUC-Ont-071663	Oreochromis niloticus	65.67	0.00e+00	914.00
IUUC-Oan-072934	Ornithorhynchus anatinus	88.63	0.00e+00	695.00
IUUC-Ola-086543	Oryzias latipes	65.59	0.00e+00	921.00
IUUC-Psi-093382	Pelodiscus sinensis	80.19	0.00e+00	1877.00
IUUC-Pma-094687	Petromyzon marinus	52.94	5.00e-95	341.00
IUUC-Pno-094984	Phaeosphaeria nodorum	45.28	2.00e-61	231.00
IUUC-Pfo-096272	Poecilia formosa	67.39	0.00e+00	891.00
IUUC-Pab-097907	Pongo abelii	74.31	0.00e+00	1080.00
IUUC-Ptt-103859	Puccinia triticina	43.84	9.00e-73	267.00
IUUC-Pte-104241	Pyrenophora teres	42.42	8.00e-61	229.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	42.42	5.00e-60	226.00
IUUC-Ssc-115918	Sus scrofa	69.57	0.00e+00	737.00
IUUC-Tru-118638	Takifugu rubripes	65.38	0.00e+00	902.00
IUUC-Tme-127054	Tuber melanosporum	40.82	1.00e-51	198.00
IUUC-Ttr-128821	Tursiops truncatus	66.36	0.00e+00	937.00
IUUC-Xtr-131823	Xenopus tropicalis	69.26	0.00e+00	971.00
IUUC-Xma-133305	Xiphophorus maculatus	65.53	0.00e+00	893.00
IUUC-Yli-134626	Yarrowia lipolytica	42.01	9.00e-55	207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence