iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033709

UUCD1 version

UUC-EqC-00417

Ensembl Protein ID

ENSECAP00000014811.1

UniProt Accession

F6WVI4; F6WVI4_HORSE

Protein Name

Uncharacterized protein

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000017033.1	ENSECAT00000018167.1	ENSECAP00000014811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.10e-12	44.9	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           Htd v  l+f  s+  ++s+s D+t+k+W+
   Q: 91   HTDQVLHLSFshSGYQFASCSKDCTVKIWN 120
           9*********955588*************9 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDEAGTPLLP DSLVYQIFLS LGPADVLAAG LVCRQWQAVS RDEFLWREQF YRYYQVARDV 60
PRHPAATSWY EEFRRLYDMV PCVEVQTLRE HTDQVLHLSF SHSGYQFASC SKDCTVKIWN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCGCCTG GGCAGAATGT CACGATGGAC GAGGCGGGCA CGCCCCTGCT CCCTGACAGC 60
CTGGTCTACC AGATCTTCCT GAGCTTGGGC CCTGCCGACG TCTTGGCCGC TGGGCTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0000151--C:ubiquitin ligase complex
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

ecb:100067988

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	92.63	0.00e+00	1004.00
IUUC-Apl-003274	Anas platyrhynchos	76.03	0.00e+00	750.00
IUUC-Aca-004626	Anolis carolinensis	59.94	2.00e-97	348.00
IUUC-Ame-011823	Astyanax mexicanus	61.02	2.00e-177	615.00
IUUC-Bta-012523	Bos taurus	91.89	0.00e+00	1007.00
IUUC-Cja-018729	Callithrix jacchus	91.40	0.00e+00	1036.00
IUUC-Cfa-020303	Canis familiaris	92.81	0.00e+00	1049.00
IUUC-Cpo-022134	Cavia porcellus	90.16	0.00e+00	1034.00
IUUC-Csa-023253	Chlorocebus sabaeus	91.90	0.00e+00	1060.00
IUUC-Cin-025742	Ciona intestinalis	34.85	8.00e-80	291.00
IUUC-Dre-027511	Danio rerio	68.41	0.00e+00	728.00
IUUC-Dno-029044	Dasypus novemcinctus	88.38	0.00e+00	989.00
IUUC-Dor-030565	Dipodomys ordii	89.28	0.00e+00	1016.00
IUUC-Dme-031713	Drosophila melanogaster	40.27	3.00e-125	442.00
IUUC-Eeu-035093	Erinaceus europaeus	95.58	1.00e-102	367.00
IUUC-Fca-035674	Felis catus	93.32	0.00e+00	1064.00
IUUC-Fal-037104	Ficedula albicollis	73.39	0.00e+00	794.00
IUUC-Gmo-039041	Gadus morhua	62.19	0.00e+00	647.00
IUUC-Gga-041230	Gallus gallus	74.19	0.00e+00	855.00
IUUC-Gac-042594	Gasterosteus aculeatus	62.39	0.00e+00	655.00
IUUC-Ggo-044486	Gorilla gorilla	91.37	0.00e+00	1026.00
IUUC-Hsa-045701	Homo sapiens	91.20	0.00e+00	1025.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	90.02	0.00e+00	1050.00
IUUC-Kpa-049204	Komagataella pastoris	31.88	3.00e-06	47.00
IUUC-Lch-050058	Latimeria chalumnae	69.38	0.00e+00	815.00
IUUC-Loc-052525	Lepisosteus oculatus	70.18	0.00e+00	726.00
IUUC-Laf-054120	Loxodonta africana	88.42	0.00e+00	993.00
IUUC-Mcc-054915	Macaca mulatta	91.90	0.00e+00	1033.00
IUUC-Meu-056715	Macropus eugenii	77.80	0.00e+00	882.00
IUUC-Mga-059831	Meleagris gallopavo	74.10	0.00e+00	760.00
IUUC-Mvi-060236	Microbotryum violaceum	38.03	1.00e-07	52.40
IUUC-Mmr-060655	Microcebus murinus	91.39	0.00e+00	1036.00
IUUC-Mdo-062641	Monodelphis domestica	82.35	0.00e+00	928.00
IUUC-Mmu-063471	Mus musculus	88.15	0.00e+00	1009.00
IUUC-Mpu-066586	Mustela putorius furo	93.68	0.00e+00	1052.00
IUUC-Nle-069429	Nomascus leucogenys	91.55	0.00e+00	1057.00
IUUC-Ont-071780	Oreochromis niloticus	66.15	0.00e+00	709.00
IUUC-Ola-086458	Oryzias latipes	66.67	0.00e+00	727.00
IUUC-Oga-088739	Otolemur garnettii	90.88	0.00e+00	1045.00
IUUC-Oar-089275	Ovis aries	95.35	8.00e-48	181.00
IUUC-Ptr-090716	Pan troglodytes	89.96	0.00e+00	842.00
IUUC-Pan-092182	Papio anubis	83.45	0.00e+00	904.00
IUUC-Psi-093449	Pelodiscus sinensis	75.51	0.00e+00	853.00
IUUC-Pma-094289	Petromyzon marinus	52.79	3.00e-172	598.00
IUUC-Pfo-096062	Poecilia formosa	66.09	0.00e+00	712.00
IUUC-Pab-098726	Pongo abelii	90.85	0.00e+00	1021.00
IUUC-Pca-100163	Procavia capensis	83.33	5.00e-84	304.00
IUUC-Pva-103051	Pteropus vampyrus	93.21	1.00e-145	509.00
IUUC-Rno-105707	Rattus norvegicus	88.75	0.00e+00	1016.00
IUUC-Sha-107074	Sarcophilus harrisii	82.54	0.00e+00	871.00
IUUC-Ssc-116020	Sus scrofa	91.80	0.00e+00	855.00
IUUC-Tgu-116683	Taeniopygia guttata	69.86	3.00e-92	330.00
IUUC-Tru-118143	Takifugu rubripes	65.05	0.00e+00	702.00
IUUC-Tni-120777	Tetraodon nigroviridis	66.26	0.00e+00	711.00
IUUC-Ttr-128439	Tursiops truncatus	91.02	0.00e+00	1021.00
IUUC-Xtr-132774	Xenopus tropicalis	56.83	4.00e-144	504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence