iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054915

Ensembl Protein ID

ENSMMUP00000015134.3

UniProt Accession

H9FW16; F7C048; H9FW16_MACMU

Genbank Protein ID

AFE78825.1; AFH32880.1; AFI37499.1

Protein Name

F-box/WD repeat-containing protein 5

Genbank Nucleotide ID

JSUE03013794; JU476076; JV047428

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011528.3	ENSMMUT00000016147.3	ENSMMUP00000015134.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-12	46.7	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           Htd v  l+f  s+  ++s+s D+t+k+W+
   Q: 91   HTDQVLHLSFshSGYQFASCSKDCTVKIWS 120
           9*********955588*************8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDEGGTPLLP DSLVYQIFLS LGPADVLAAG LVCRQWQAVS RDEFLWREQF YRYYQVARDV 60
PRHPAATSWY EEFQRLYDTV PCVEVQTLRE HTDQVLHLSF SHSGYQFASC SKDCTVKIWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCGCCCG GAGCTGCCGG GTCCTTGGTT GGACGGCGGT GCCCGGGCGT CCCCTGCAGA 60
CACCCAGCCC CGTGGAACTC CCGGCAGGAC GGTTGGGGCG GGAGGAACCG GGCGCCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

mcc:721653

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	90.70	0.00e+00	1011.00
IUUC-Apl-003274	Anas platyrhynchos	77.67	0.00e+00	781.00
IUUC-Aca-004626	Anolis carolinensis	61.29	7.00e-99	353.00
IUUC-Ame-011823	Astyanax mexicanus	61.61	1.00e-177	616.00
IUUC-Bta-012523	Bos taurus	90.62	0.00e+00	1027.00
IUUC-Cja-018729	Callithrix jacchus	95.60	0.00e+00	1112.00
IUUC-Cfa-020303	Canis familiaris	91.05	0.00e+00	1045.00
IUUC-Cpo-022134	Cavia porcellus	92.44	0.00e+00	1072.00
IUUC-Csa-023253	Chlorocebus sabaeus	99.65	0.00e+00	1170.00
IUUC-Cin-025742	Ciona intestinalis	34.33	3.00e-81	295.00
IUUC-Dre-027511	Danio rerio	68.17	0.00e+00	736.00
IUUC-Dno-029044	Dasypus novemcinctus	89.59	0.00e+00	1022.00
IUUC-Dor-030565	Dipodomys ordii	90.51	0.00e+00	1048.00
IUUC-Dme-031713	Drosophila melanogaster	41.02	3.00e-127	449.00
IUUC-Eca-033709	Equus caballus	91.90	0.00e+00	1040.00
IUUC-Eeu-035093	Erinaceus europaeus	96.13	4.00e-103	368.00
IUUC-Fca-035674	Felis catus	90.51	0.00e+00	1038.00
IUUC-Fal-037104	Ficedula albicollis	71.62	0.00e+00	825.00
IUUC-Gmo-039041	Gadus morhua	62.90	0.00e+00	654.00
IUUC-Gga-041230	Gallus gallus	75.56	0.00e+00	886.00
IUUC-Gac-042594	Gasterosteus aculeatus	62.33	0.00e+00	657.00
IUUC-Ggo-044486	Gorilla gorilla	97.70	0.00e+00	1120.00
IUUC-Hsa-045701	Homo sapiens	97.35	0.00e+00	1118.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	91.59	0.00e+00	1075.00
IUUC-Kpa-049204	Komagataella pastoris	31.88	3.00e-06	47.40
IUUC-Lch-050058	Latimeria chalumnae	70.52	0.00e+00	833.00
IUUC-Loc-052525	Lepisosteus oculatus	71.35	0.00e+00	738.00
IUUC-Laf-054120	Loxodonta africana	88.73	0.00e+00	1030.00
IUUC-Meu-056715	Macropus eugenii	79.30	0.00e+00	924.00
IUUC-Mga-059831	Meleagris gallopavo	75.43	0.00e+00	791.00
IUUC-Mvi-060236	Microbotryum violaceum	35.90	5.00e-07	50.40
IUUC-Mmr-060655	Microcebus murinus	92.95	0.00e+00	1089.00
IUUC-Mdo-062641	Monodelphis domestica	83.56	0.00e+00	966.00
IUUC-Mmu-063471	Mus musculus	89.57	0.00e+00	1042.00
IUUC-Mpu-066586	Mustela putorius furo	90.70	0.00e+00	1026.00
IUUC-Nle-069429	Nomascus leucogenys	98.06	0.00e+00	1151.00
IUUC-Ont-071780	Oreochromis niloticus	67.07	0.00e+00	717.00
IUUC-Ola-086458	Oryzias latipes	66.00	0.00e+00	733.00
IUUC-Oga-088739	Otolemur garnettii	92.43	0.00e+00	1093.00
IUUC-Oar-089275	Ovis aries	94.19	3.00e-47	179.00
IUUC-Ptr-090716	Pan troglodytes	97.06	0.00e+00	931.00
IUUC-Pan-092182	Papio anubis	91.34	0.00e+00	1011.00
IUUC-Psi-093449	Pelodiscus sinensis	76.19	0.00e+00	887.00
IUUC-Pma-094289	Petromyzon marinus	54.12	4.00e-175	607.00
IUUC-Pfo-096062	Poecilia formosa	66.44	0.00e+00	724.00
IUUC-Pab-098726	Pongo abelii	96.48	0.00e+00	1102.00
IUUC-Pca-100163	Procavia capensis	82.81	8.00e-92	330.00
IUUC-Pva-103051	Pteropus vampyrus	89.93	9.00e-147	513.00
IUUC-Rno-105707	Rattus norvegicus	90.37	0.00e+00	1043.00
IUUC-Sha-107074	Sarcophilus harrisii	83.82	0.00e+00	913.00
IUUC-Ssc-116020	Sus scrofa	89.34	0.00e+00	853.00
IUUC-Tgu-116683	Taeniopygia guttata	69.18	2.00e-99	355.00
IUUC-Tru-118143	Takifugu rubripes	65.35	0.00e+00	705.00
IUUC-Tni-120777	Tetraodon nigroviridis	66.32	0.00e+00	714.00
IUUC-Ttr-128439	Tursiops truncatus	90.46	0.00e+00	1034.00
IUUC-Xtr-132774	Xenopus tropicalis	56.92	4.00e-150	524.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence