iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089922

Ensembl Protein ID

ENSOARP00000005336.1

UniProt Accession

W5P4I3; W5P4I3_SHEEP

Genbank Protein ID

ENSOARP00000005336

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01043337

Gene Name

TRAF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004978.1	ENSOART00000005423.1	ENSOARP00000005336.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.73	0.00e+00	1069.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MEPSKKLDAA GTLPANPPLK LHPERGAGPA VLVPEQGGYK ERFVKAVEDK YKCEKCRLVL 60
CSPKQTECGH RFCETCMGAL LSSSSPKCTA CQEVIIKDKV FKDNCCKREI LALQIFCRNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGGGACT CCACTACAGT ATCTGAAGAA GGATAAAGTT GACTCTGCTT TGCTTCTTTC 60
TTTATTGAAG TTTCTTCCTG CCTGGTCAAG GTCAGATATA TCCTCTTGCA GCATACAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0050688--P:regulation of defense response to virus
GO:0032648--P:regulation of interferon-beta production
GO:0030162--P:regulation of proteolysis
GO:0008063--P:Toll signaling pathway
GO:0002224--P:toll-like receptor signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	92.31	0.00e+00	1086.00
IUUC-Apl-004189	Anas platyrhynchos	84.48	0.00e+00	997.00
IUUC-Aca-004540	Anolis carolinensis	81.25	0.00e+00	969.00
IUUC-Ate-010296	Aspergillus terreus	25.79	5.00e-17	82.00
IUUC-Ame-010645	Astyanax mexicanus	54.74	2.00e-174	605.00
IUUC-Bgr-012191	Blumeria graminis	25.66	7.00e-15	75.10
IUUC-Bta-013140	Bos taurus	95.63	0.00e+00	1120.00
IUUC-Cja-019436	Callithrix jacchus	91.43	0.00e+00	1078.00
IUUC-Cfa-021072	Canis familiaris	91.43	0.00e+00	1080.00
IUUC-Cpo-022472	Cavia porcellus	91.96	0.00e+00	1080.00
IUUC-Csa-024217	Chlorocebus sabaeus	90.73	0.00e+00	1071.00
IUUC-Cho-025066	Choloepus hoffmanni	90.00	1.00e-173	602.00
IUUC-Cin-025234	Ciona intestinalis	29.21	2.00e-50	193.00
IUUC-Csv-026078	Ciona savignyi	61.88	2.00e-69	254.00
IUUC-Dre-028208	Danio rerio	51.72	3.00e-161	561.00
IUUC-Dno-028868	Dasypus novemcinctus	90.03	0.00e+00	1063.00
IUUC-Dor-031056	Dipodomys ordii	92.45	0.00e+00	931.00
IUUC-Ete-033005	Echinops telfairi	89.67	3.00e-162	564.00
IUUC-Eca-033717	Equus caballus	91.43	0.00e+00	1077.00
IUUC-Eeu-035172	Erinaceus europaeus	83.51	0.00e+00	626.00
IUUC-Fca-035688	Felis catus	91.97	0.00e+00	1082.00
IUUC-Fal-037176	Ficedula albicollis	84.18	0.00e+00	997.00
IUUC-Gmo-038931	Gadus morhua	52.65	7.00e-155	540.00
IUUC-Gac-042019	Gasterosteus aculeatus	53.80	7.00e-165	573.00
IUUC-Ggo-044424	Gorilla gorilla	90.91	0.00e+00	1072.00
IUUC-Hsa-046957	Homo sapiens	90.73	0.00e+00	1069.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	91.08	0.00e+00	1070.00
IUUC-Lch-050680	Latimeria chalumnae	66.18	0.00e+00	774.00
IUUC-Loc-052093	Lepisosteus oculatus	55.87	0.00e+00	645.00
IUUC-Laf-054573	Loxodonta africana	82.52	0.00e+00	957.00
IUUC-Mcc-055049	Macaca mulatta	90.38	0.00e+00	1066.00
IUUC-Mga-059244	Meleagris gallopavo	83.77	0.00e+00	991.00
IUUC-Mmr-061469	Microcebus murinus	91.96	0.00e+00	1082.00
IUUC-Mdo-063049	Monodelphis domestica	87.15	0.00e+00	1030.00
IUUC-Mmu-063763	Mus musculus	91.96	0.00e+00	1082.00
IUUC-Mpu-065956	Mustela putorius furo	91.62	0.00e+00	1044.00
IUUC-Mlu-067482	Myotis lucifugus	89.69	0.00e+00	1059.00
IUUC-Nle-069941	Nomascus leucogenys	91.08	0.00e+00	1075.00
IUUC-Opr-071027	Ochotona princeps	77.45	0.00e+00	847.00
IUUC-Ont-071914	Oreochromis niloticus	54.12	8.00e-177	613.00
IUUC-Oan-072802	Ornithorhynchus anatinus	87.06	0.00e+00	1022.00
IUUC-Ocu-074075	Oryctolagus cuniculus	91.78	0.00e+00	1081.00
IUUC-Oga-088149	Otolemur garnettii	91.26	0.00e+00	1080.00
IUUC-Ptr-091412	Pan troglodytes	90.73	0.00e+00	1069.00
IUUC-Pan-092789	Papio anubis	90.73	0.00e+00	1071.00
IUUC-Psi-093603	Pelodiscus sinensis	82.59	0.00e+00	963.00
IUUC-Pma-094463	Petromyzon marinus	47.71	6.00e-132	464.00
IUUC-Pfo-096518	Poecilia formosa	54.11	3.00e-176	611.00
IUUC-Pab-097664	Pongo abelii	90.91	0.00e+00	1072.00
IUUC-Pca-100821	Procavia capensis	94.54	3.00e-134	471.00
IUUC-Pva-103201	Pteropus vampyrus	80.07	0.00e+00	926.00
IUUC-Rno-105505	Rattus norvegicus	91.08	0.00e+00	1073.00
IUUC-Sha-107416	Sarcophilus harrisii	87.41	0.00e+00	1026.00
IUUC-Sar-113438	Sorex araneus	92.47	1.00e-99	356.00
IUUC-Ssc-115351	Sus scrofa	93.18	0.00e+00	1095.00
IUUC-Tgu-116608	Taeniopygia guttata	85.64	0.00e+00	996.00
IUUC-Tru-117964	Takifugu rubripes	54.95	4.00e-169	587.00
IUUC-Tni-120211	Tetraodon nigroviridis	53.92	4.00e-172	597.00
IUUC-Tur-126245	Triticum urartu	25.38	2.00e-07	50.10
IUUC-Tbe-127700	Tupaia belangeri	74.69	1.00e-135	476.00
IUUC-Ttr-128450	Tursiops truncatus	95.00	0.00e+00	631.00
IUUC-Vda-129938	Verticillium dahliae	25.98	1.00e-20	94.40
IUUC-Vpa-130074	Vicugna pacos	93.02	0.00e+00	842.00
IUUC-Xtr-132563	Xenopus tropicalis	75.00	0.00e+00	904.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence