iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000013067.1	ENSONIT00000016446.1	ENSONIP00000016431.1
ENSONIG00000013067.1	ENSONIT00000016447.1	ENSONIP00000016432.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-19	69.4	818	869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            + y++ a +  eL+l++Gd+v++ +k   d+gW+kg  e++g+ G fP+ +v 
   Q: 818  VARYNFAARDMRELSLREGDIVKIYSKIGGDQGWWKG--EANGRIGWFPSTYVD 869
           578**********************************..9************96 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MEEWRQCGRW LIDCKVLPPN HRVVWPSSAV FDLAQALRDG VLLCQMLHNL SPGSVDLKEI 60
NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SELFDPFDLF DVRDFGKVIS ALSRISHHSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGT GGAGACAATG TGGACGGTGG TTGATAGACT GCAAGGTCCT GCCCCCGAAC 60
CACCGGGTTG TGTGGCCCTC CTCGGCCGTC TTCGACTTGG CACAGGCCCT GCGTGATGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	80.31	0.00e+00	1287.00
IUUC-Apl-003262	Anas platyrhynchos	81.64	0.00e+00	1373.00
IUUC-Ame-011608	Astyanax mexicanus	87.19	0.00e+00	1560.00
IUUC-Bta-013147	Bos taurus	78.57	0.00e+00	1100.00
IUUC-Bra-017317	Brassica rapa	33.33	4.40e-01	30.00
IUUC-Cel-018578	Caenorhabditis elegans	34.18	8.00e-81	295.00
IUUC-Cja-018877	Callithrix jacchus	77.56	0.00e+00	1195.00
IUUC-Cfa-020315	Canis familiaris	76.33	0.00e+00	1036.00
IUUC-Cpo-021543	Cavia porcellus	78.25	0.00e+00	1117.00
IUUC-Csa-024204	Chlorocebus sabaeus	79.31	0.00e+00	1385.00
IUUC-Cin-025115	Ciona intestinalis	36.05	8.00e-150	524.00
IUUC-Csv-025995	Ciona savignyi	36.41	2.00e-155	543.00
IUUC-Dre-028308	Danio rerio	91.27	0.00e+00	1625.00
IUUC-Dno-029584	Dasypus novemcinctus	73.30	0.00e+00	971.00
IUUC-Dor-031014	Dipodomys ordii	70.03	0.00e+00	1029.00
IUUC-Eca-033448	Equus caballus	79.25	0.00e+00	1363.00
IUUC-Eeu-035182	Erinaceus europaeus	72.70	3.00e-169	589.00
IUUC-Fca-035460	Felis catus	77.90	0.00e+00	1108.00
IUUC-Fal-036684	Ficedula albicollis	81.03	0.00e+00	1397.00
IUUC-Gmo-038816	Gadus morhua	84.28	0.00e+00	1215.00
IUUC-Gga-040999	Gallus gallus	78.68	0.00e+00	1348.00
IUUC-Gac-041353	Gasterosteus aculeatus	86.42	0.00e+00	1292.00
IUUC-Ggo-044558	Gorilla gorilla	81.38	0.00e+00	1402.00
IUUC-Hsa-046208	Homo sapiens	81.27	0.00e+00	1401.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	75.98	0.00e+00	1015.00
IUUC-Loc-052827	Lepisosteus oculatus	89.00	0.00e+00	1585.00
IUUC-Laf-054009	Loxodonta africana	78.25	0.00e+00	1340.00
IUUC-Mcc-055054	Macaca mulatta	80.93	0.00e+00	1395.00
IUUC-Mga-060106	Meleagris gallopavo	81.64	0.00e+00	1380.00
IUUC-Mmr-061118	Microcebus murinus	80.34	0.00e+00	1370.00
IUUC-Mdo-062380	Monodelphis domestica	76.57	0.00e+00	1110.00
IUUC-Mmu-063135	Mus musculus	81.53	0.00e+00	1407.00
IUUC-Mpu-066135	Mustela putorius furo	77.87	0.00e+00	1233.00
IUUC-Nle-069465	Nomascus leucogenys	75.06	0.00e+00	1268.00
IUUC-Oan-073384	Ornithorhynchus anatinus	77.98	0.00e+00	1073.00
IUUC-Ola-087499	Oryzias latipes	85.67	0.00e+00	1202.00
IUUC-Oga-088444	Otolemur garnettii	75.87	0.00e+00	1095.00
IUUC-Oar-089576	Ovis aries	74.59	0.00e+00	1009.00
IUUC-Ptr-090507	Pan troglodytes	81.28	0.00e+00	1389.00
IUUC-Pan-092325	Papio anubis	78.42	0.00e+00	1340.00
IUUC-Psi-094021	Pelodiscus sinensis	78.77	0.00e+00	1343.00
IUUC-Pma-094372	Petromyzon marinus	52.37	0.00e+00	700.00
IUUC-Pfo-096732	Poecilia formosa	93.53	0.00e+00	1653.00
IUUC-Pab-098426	Pongo abelii	66.09	0.00e+00	971.00
IUUC-Pca-100295	Procavia capensis	80.56	0.00e+00	1288.00
IUUC-Rno-105332	Rattus norvegicus	80.94	0.00e+00	1372.00
IUUC-Sha-106529	Sarcophilus harrisii	80.00	0.00e+00	1095.00
IUUC-Ssc-116176	Sus scrofa	79.39	0.00e+00	1246.00
IUUC-Tgu-116917	Taeniopygia guttata	81.09	0.00e+00	1253.00
IUUC-Tru-118398	Takifugu rubripes	91.00	0.00e+00	1145.00
IUUC-Tni-120819	Tetraodon nigroviridis	91.19	0.00e+00	1384.00
IUUC-Xtr-132747	Xenopus tropicalis	74.43	0.00e+00	1296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence