iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092102

Ensembl Protein ID

ENSPANP00000006150.1

UniProt Accession

A0A096N1H8; A0A096N1H8_PAPAN

Genbank Protein ID

ENSPANP00000006150

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AHZZ01061847

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000000719.1	ENSPANT00000013052.1	ENSPANP00000006150.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-29	101.8	1020	1071

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
           +C+vC +++++e+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1020 SCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADigFDCSMCR 1071
           6********************************999999998899******8 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MDGLETTETE TIVETAEIKE QSAEEDAEAE ADNSKQLIPA LQRSVSEESA NSLVSVGVEA 60
KISEQLCAFC YCGEKSSLGQ GDLKQFRVTP GFILPWRNQP SNKKDIDDNS NGTYEKMQNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCCCGGCC CCGAGCCCCG CAGCCGCAGA CAAAAGACCT CGGGGCCGGC CTCGCAAAGA 60
TGGCGCTTCC CCTTTCCAGA GAGCCAGAAA GAAGTAAGTT GAGTGCGAGG GAGCCAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	85.74	0.00e+00	7111.00
IUUC-Apl-003311	Anas platyrhynchos	71.36	0.00e+00	5631.00
IUUC-Aca-004705	Anolis carolinensis	65.36	0.00e+00	5129.00
IUUC-Bta-012322	Bos taurus	81.38	0.00e+00	6593.00
IUUC-Cel-018354	Caenorhabditis elegans	35.38	1.00e-64	243.00
IUUC-Cja-019983	Callithrix jacchus	93.20	0.00e+00	7901.00
IUUC-Cfa-020903	Canis familiaris	85.28	0.00e+00	7180.00
IUUC-Cpo-021732	Cavia porcellus	82.47	0.00e+00	6885.00
IUUC-Csa-023083	Chlorocebus sabaeus	95.72	0.00e+00	6256.00
IUUC-Cho-024469	Choloepus hoffmanni	79.86	0.00e+00	2226.00
IUUC-Dre-028110	Danio rerio	63.79	0.00e+00	1241.00
IUUC-Dor-030569	Dipodomys ordii	79.52	0.00e+00	4491.00
IUUC-Dme-031590	Drosophila melanogaster	31.48	8.00e-68	252.00
IUUC-Eca-033945	Equus caballus	84.72	0.00e+00	5016.00
IUUC-Fca-035922	Felis catus	83.36	0.00e+00	6811.00
IUUC-Gac-041896	Gasterosteus aculeatus	44.53	0.00e+00	1724.00
IUUC-Ggo-044812	Gorilla gorilla	92.68	0.00e+00	7824.00
IUUC-Hsa-046595	Homo sapiens	94.85	0.00e+00	8052.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	85.05	0.00e+00	6984.00
IUUC-Lch-050086	Latimeria chalumnae	55.04	0.00e+00	2532.00
IUUC-Loc-052891	Lepisosteus oculatus	49.18	0.00e+00	2048.00
IUUC-Laf-054348	Loxodonta africana	81.39	0.00e+00	3010.00
IUUC-Mcc-054868	Macaca mulatta	96.60	0.00e+00	8185.00
IUUC-Meu-056322	Macropus eugenii	63.19	0.00e+00	1120.00
IUUC-Mga-059541	Meleagris gallopavo	70.64	0.00e+00	5527.00
IUUC-Mmr-061092	Microcebus murinus	85.96	0.00e+00	5564.00
IUUC-Mdo-062610	Monodelphis domestica	73.50	0.00e+00	1942.00
IUUC-Mmu-063666	Mus musculus	83.20	0.00e+00	6846.00
IUUC-Mpu-066366	Mustela putorius furo	83.63	0.00e+00	6613.00
IUUC-Mlu-068201	Myotis lucifugus	79.53	0.00e+00	3998.00
IUUC-Nle-069232	Nomascus leucogenys	93.32	0.00e+00	6081.00
IUUC-Opr-070625	Ochotona princeps	72.66	0.00e+00	1226.00
IUUC-Ont-072401	Oreochromis niloticus	57.26	0.00e+00	1058.00
IUUC-Oan-072945	Ornithorhynchus anatinus	70.06	0.00e+00	4043.00
IUUC-Ocu-074920	Oryctolagus cuniculus	81.93	0.00e+00	5241.00
IUUC-Ola-086436	Oryzias latipes	43.92	0.00e+00	1724.00
IUUC-Oga-088637	Otolemur garnettii	84.01	0.00e+00	4447.00
IUUC-Oar-089363	Ovis aries	79.38	0.00e+00	6405.00
IUUC-Ptr-091527	Pan troglodytes	94.81	0.00e+00	8101.00
IUUC-Pma-094252	Petromyzon marinus	39.43	0.00e+00	673.00
IUUC-Pfo-096288	Poecilia formosa	45.52	0.00e+00	1248.00
IUUC-Pab-098241	Pongo abelii	95.31	0.00e+00	5308.00
IUUC-Pca-100103	Procavia capensis	77.86	0.00e+00	1497.00
IUUC-Pva-102238	Pteropus vampyrus	75.76	0.00e+00	2509.00
IUUC-Rno-105395	Rattus norvegicus	70.87	0.00e+00	1006.00
IUUC-Sha-106550	Sarcophilus harrisii	71.13	0.00e+00	4283.00
IUUC-Sar-113183	Sorex araneus	64.37	0.00e+00	677.00
IUUC-Tgu-116677	Taeniopygia guttata	71.13	0.00e+00	5404.00
IUUC-Tru-118037	Takifugu rubripes	46.43	0.00e+00	1352.00
IUUC-Tsy-118932	Tarsius syrichta	89.50	0.00e+00	5452.00
IUUC-Tni-119970	Tetraodon nigroviridis	46.02	0.00e+00	1757.00
IUUC-Ttr-129051	Tursiops truncatus	81.91	0.00e+00	6547.00
IUUC-Vpa-130236	Vicugna pacos	80.07	0.00e+00	1878.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence