iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107469

Ensembl Protein ID

ENSSHAP00000011944.1

UniProt Accession

G3W939; G3W939_SARHA

Genbank Protein ID

ENSSHAP00000011944

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01018685

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010249.1	ENSSHAT00000012042.1	ENSSHAP00000011944.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	33.61	4.00e-09	59.30	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	61.08	2.00e-120	430.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	61.08	2.00e-120	430.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	61.54	2.00e-126	449.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	59.64	2.00e-123	439.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MERTSRGGRC NKTGKVDEDR DLIAFSSDEE LCMGMCYVKE GLFRIYIKEK KECKREHRPS 60
AQEAPSNVVH PNVICDGCNG PVVGNRFKCT ICPDYDLCSS CESKGLHKEH NMVIFQNPIT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNCGAAC AAACTTGTAA AACAACTTGG GATCCCCACG GCTTGGGCCA GGCCGAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

KEGG

shr:100924705

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	58.03	4.00e-116	410.00
IUUC-Apl-003897	Anas platyrhynchos	58.00	6.00e-116	410.00
IUUC-Aca-004699	Anolis carolinensis	49.23	6.00e-86	311.00
IUUC-Ame-010982	Astyanax mexicanus	44.41	2.00e-63	236.00
IUUC-Bta-012634	Bos taurus	59.74	5.00e-124	437.00
IUUC-Cel-018540	Caenorhabditis elegans	40.79	3.00e-12	67.00
IUUC-Cja-019684	Callithrix jacchus	60.16	2.00e-121	429.00
IUUC-Cfa-020573	Canis familiaris	51.83	1.00e-85	310.00
IUUC-Cpo-021425	Cavia porcellus	55.58	1.00e-106	379.00
IUUC-Csa-023968	Chlorocebus sabaeus	59.90	2.00e-117	415.00
IUUC-Cho-024596	Choloepus hoffmanni	61.11	2.00e-35	142.00
IUUC-Cin-025557	Ciona intestinalis	57.14	2.00e-09	56.20
IUUC-Csv-025974	Ciona savignyi	50.00	9.00e-08	50.80
IUUC-Cne-027045	Cryptococcus neoformans	41.54	4.00e-09	57.40
IUUC-Dre-028621	Danio rerio	43.43	4.00e-78	285.00
IUUC-Dno-029060	Dasypus novemcinctus	58.81	3.00e-122	431.00
IUUC-Dor-030547	Dipodomys ordii	56.40	4.00e-64	238.00
IUUC-Dme-031659	Drosophila melanogaster	33.61	5.00e-10	59.30
IUUC-Ete-033201	Echinops telfairi	54.71	3.00e-110	391.00
IUUC-Eca-033456	Equus caballus	58.96	9.00e-122	429.00
IUUC-Eeu-035157	Erinaceus europaeus	57.70	1.00e-118	419.00
IUUC-Fca-035403	Felis catus	58.96	2.00e-119	422.00
IUUC-Fal-036798	Ficedula albicollis	61.62	9.00e-124	436.00
IUUC-Gmo-039619	Gadus morhua	43.13	8.00e-41	160.00
IUUC-Gga-040137	Gallus gallus	60.76	5.00e-120	424.00
IUUC-Gac-042410	Gasterosteus aculeatus	45.59	2.00e-85	309.00
IUUC-Ggo-044690	Gorilla gorilla	60.00	8.00e-119	420.00
IUUC-Hsa-046390	Homo sapiens	60.26	5.00e-119	421.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	60.26	1.00e-122	433.00
IUUC-Lch-049658	Latimeria chalumnae	48.61	1.00e-102	366.00
IUUC-Loc-052589	Lepisosteus oculatus	46.94	7.00e-93	333.00
IUUC-Laf-053746	Loxodonta africana	54.17	2.00e-106	379.00
IUUC-Mcc-055635	Macaca mulatta	59.53	6.00e-120	423.00
IUUC-Meu-056528	Macropus eugenii	49.74	6.00e-81	293.00
IUUC-Mga-059458	Meleagris gallopavo	60.00	1.00e-118	419.00
IUUC-Mmr-061539	Microcebus murinus	51.35	2.00e-62	232.00
IUUC-Mdo-063083	Monodelphis domestica	71.98	2.00e-153	535.00
IUUC-Mmu-063589	Mus musculus	61.54	3.00e-125	441.00
IUUC-Mpu-065727	Mustela putorius furo	58.44	8.00e-121	426.00
IUUC-Mlu-067026	Myotis lucifugus	58.44	1.00e-123	435.00
IUUC-Nle-069356	Nomascus leucogenys	42.86	1.00e-63	236.00
IUUC-Opr-071091	Ochotona princeps	45.78	7.00e-48	184.00
IUUC-Ont-071864	Oreochromis niloticus	49.10	5.00e-92	331.00
IUUC-Oan-073308	Ornithorhynchus anatinus	61.27	4.00e-123	434.00
IUUC-Ocu-074110	Oryctolagus cuniculus	60.78	6.00e-125	440.00
IUUC-Ola-086944	Oryzias latipes	47.11	7.00e-43	166.00
IUUC-Oga-088869	Otolemur garnettii	57.72	1.00e-121	429.00
IUUC-Oar-089857	Ovis aries	59.18	6.00e-124	437.00
IUUC-Ptr-091640	Pan troglodytes	60.26	5.00e-119	421.00
IUUC-Pan-092831	Papio anubis	58.63	2.00e-119	422.00
IUUC-Psi-093925	Pelodiscus sinensis	60.15	1.00e-116	412.00
IUUC-Pma-094576	Petromyzon marinus	28.57	2.00e-20	93.20
IUUC-Pfo-097297	Poecilia formosa	46.12	7.00e-77	280.00
IUUC-Pab-098725	Pongo abelii	55.61	5.00e-100	357.00
IUUC-Pca-101106	Procavia capensis	58.70	1.00e-116	412.00
IUUC-Pva-102710	Pteropus vampyrus	53.87	4.00e-90	325.00
IUUC-Rno-105539	Rattus norvegicus	59.64	2.00e-124	439.00
IUUC-Ssc-115526	Sus scrofa	60.00	1.00e-122	432.00
IUUC-Tgu-117194	Taeniopygia guttata	61.04	2.00e-121	429.00
IUUC-Tru-117896	Takifugu rubripes	46.02	5.00e-85	308.00
IUUC-Tni-119943	Tetraodon nigroviridis	46.49	6.00e-81	294.00
IUUC-Ttr-128676	Tursiops truncatus	60.26	2.00e-121	428.00
IUUC-Vda-129812	Verticillium dahliae	34.48	9.00e-08	52.00
IUUC-Vpa-130319	Vicugna pacos	72.73	5.00e-42	164.00
IUUC-Xtr-132907	Xenopus tropicalis	54.46	1.00e-117	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence