iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091435

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03095798

Gene Name

ATXN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006648.6	ENSPTRT00000047710.4	ENSPTRP00000044008.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UIM	2.40e-09	36.1	224	242
UBD/Alpha-Helix/UIM	6.8e-06	16.2	244	260
UBD/Alpha-Helix/UIM	9.3e-05	12.8	335	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +++e+Lq+AlalS+qE ++
   Q: 224  EDEEDLQRALALSRQEIDM 242
           69**************886 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEe 17
           dE+++L++A++lS+q  
   Q: 244  DEEADLRRAIQLSMQGS 260
           7*************976 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqE 16
           +E+++Lq A+++Sl+ 
   Q: 335  SEEDMLQAAVTMSLET 350
           7*************96 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERMRMAE GGVTSEDYRT 60
FLQQPSGNMD DSGFFSIQVI SNALKVWGLE LILFNSPEYQ RLRIDPINER SFICNYKEHW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGCCGTT GGCTCCAGAC AAATAAACAT GGAGTCCATC TTCCACGAGA AAGTGAGTGT 60
CCGTGTTCGG NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR009068--S15_NS1_RNA-bd
IPR011990--TPR-like_helical_dom
IPR003903--UIM_dom

PROSITE

PS50957--JOSEPHIN
PS50330--UIM

Pfam

PF02099--Josephin
PF02809--UIM

SMART

SM01246--Josephin
SM00726--UIM

Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030036--P:actin cytoskeleton organization
GO:0045104--P:intermediate filament cytoskeleton organization
GO:0000226--P:microtubule cytoskeleton organization
GO:1904294--P:positive regulation of ERAD pathway
GO:1904379--P:protein localization to cytosolic proteasome complex involved in ERAD pathway
GO:0010810--P:regulation of cell-substrate adhesion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002015	Ailuropoda melanoleuca	94.05	0.00e+00	654.00
IUUC-Apl-003210	Anas platyrhynchos	76.44	9.00e-148	516.00
IUUC-Aca-005171	Anolis carolinensis	71.93	8.00e-128	449.00
IUUC-Aly-005625	Arabidopsis lyrata	44.64	1.00e-40	160.00
IUUC-Ath-007088	Arabidopsis thaliana	44.64	8.00e-41	160.00
IUUC-Afu-009069	Aspergillus fumigatus	30.67	1.50e-01	29.30
IUUC-Ame-010715	Astyanax mexicanus	71.02	5.00e-123	433.00
IUUC-Bta-013538	Bos taurus	84.84	0.00e+00	627.00
IUUC-Bci-013745	Botrytis cinerea	34.85	1.50e-01	31.60
IUUC-Bdi-015000	Brachypodium distachyon	42.01	5.00e-36	144.00
IUUC-Bol-015894	Brassica oleracea	44.05	7.00e-41	161.00
IUUC-Bra-018020	Brassica rapa	44.31	3.00e-41	162.00
IUUC-Cel-018121	Caenorhabditis elegans	37.12	5.00e-44	171.00
IUUC-Cja-018840	Callithrix jacchus	88.89	0.00e+00	638.00
IUUC-Cfa-021035	Canis familiaris	94.72	0.00e+00	664.00
IUUC-Cpo-021776	Cavia porcellus	87.91	0.00e+00	634.00
IUUC-Cho-024878	Choloepus hoffmanni	93.45	0.00e+00	640.00
IUUC-Cgl-026754	Colletotrichum gloeosporioides	55.56	4.30e-01	30.40
IUUC-Dre-027506	Danio rerio	68.55	3.00e-90	324.00
IUUC-Dno-029172	Dasypus novemcinctus	92.82	0.00e+00	657.00
IUUC-Dor-030900	Dipodomys ordii	80.00	3.00e-150	524.00
IUUC-Ete-033000	Echinops telfairi	59.94	9.00e-93	333.00
IUUC-Eca-034338	Equus caballus	94.90	0.00e+00	652.00
IUUC-Eeu-034585	Erinaceus europaeus	98.10	2.00e-57	215.00
IUUC-Fca-035441	Felis catus	91.49	1.00e-72	264.00
IUUC-Fal-037525	Ficedula albicollis	74.66	1.00e-135	476.00
IUUC-Gmo-039718	Gadus morhua	72.16	3.00e-112	397.00
IUUC-Gga-040774	Gallus gallus	75.94	2.00e-152	531.00
IUUC-Gac-041671	Gasterosteus aculeatus	72.51	6.00e-109	386.00
IUUC-Gma-042801	Glycine max	41.32	2.00e-37	149.00
IUUC-Ggo-044759	Gorilla gorilla	88.29	2.00e-152	531.00
IUUC-Hsa-046591	Homo sapiens	95.98	0.00e+00	647.00
IUUC-Hvu-047492	Hordeum vulgare	43.20	8.00e-35	140.00
IUUC-Itr-048851	Ictidomys tridecemlineatus	77.11	6.00e-133	466.00
IUUC-Lch-049519	Latimeria chalumnae	70.81	3.00e-111	394.00
IUUC-Lpe-050819	Leersia perrieri	43.27	5.00e-36	144.00
IUUC-Loc-051816	Lepisosteus oculatus	66.76	1.00e-131	462.00
IUUC-Laf-053784	Loxodonta africana	90.03	0.00e+00	650.00
IUUC-Mcc-055283	Macaca mulatta	98.61	0.00e+00	697.00
IUUC-Meu-056589	Macropus eugenii	76.88	2.00e-153	535.00
IUUC-Mtr-058233	Medicago truncatula	34.32	2.00e-37	149.00
IUUC-Mla-059013	Melampsora laricipopulina	39.90	6.00e-31	128.00
IUUC-Mga-059301	Meleagris gallopavo	74.53	1.00e-154	539.00
IUUC-Mmr-061038	Microcebus murinus	95.07	0.00e+00	672.00
IUUC-Mdo-062927	Monodelphis domestica	81.06	3.00e-153	534.00
IUUC-Mmu-063600	Mus musculus	85.08	2.00e-165	574.00
IUUC-Mpu-065897	Mustela putorius furo	96.47	2.00e-160	558.00
IUUC-Mlu-067543	Myotis lucifugus	94.77	5.00e-162	563.00
IUUC-Nle-069847	Nomascus leucogenys	92.50	0.00e+00	642.00
IUUC-Opr-070550	Ochotona princeps	85.27	3.00e-164	570.00
IUUC-Ont-071723	Oreochromis niloticus	69.13	3.00e-111	394.00
IUUC-Oan-073569	Ornithorhynchus anatinus	79.30	6.00e-163	566.00
IUUC-Ocu-074632	Oryctolagus cuniculus	90.42	0.00e+00	638.00
IUUC-Oba-075288	Oryza barthii	43.27	3.00e-38	152.00
IUUC-Obr-076050	Oryza brachyantha	42.69	3.00e-34	139.00
IUUC-Ogl-077174	Oryza glaberrima	43.27	3.00e-38	152.00
IUUC-Ogu-078006	Oryza glumaepatula	43.27	3.00e-38	152.00
IUUC-Oin-079278	Oryza indica	40.88	6.00e-36	144.00
IUUC-Olo-080941	Oryza longistaminata	43.27	3.00e-38	152.00
IUUC-Ome-081172	Oryza meridionalis	43.27	3.00e-38	152.00
IUUC-Oni-082239	Oryza nivara	43.27	2.00e-38	152.00
IUUC-Opu-083939	Oryza punctata	42.69	1.00e-37	150.00
IUUC-Oru-084393	Oryza rufipogon	43.27	3.00e-38	152.00
IUUC-Osa-086080	Oryza sativa	43.27	2.00e-38	152.00
IUUC-Ola-087566	Oryzias latipes	73.97	4.00e-113	400.00
IUUC-Oga-088617	Otolemur garnettii	75.59	5.00e-137	479.00
IUUC-Oar-090052	Ovis aries	87.19	0.00e+00	627.00
IUUC-Psi-093313	Pelodiscus sinensis	88.72	8.00e-132	462.00
IUUC-Pma-094374	Petromyzon marinus	60.75	2.00e-85	308.00
IUUC-Pno-095003	Phaeosphaeria nodorum	34.52	9.60e-02	32.30
IUUC-Ppa-095601	Physcomitrella patens	44.64	6.00e-45	174.00
IUUC-Pfo-097327	Poecilia formosa	70.37	6.00e-113	400.00
IUUC-Pab-098611	Pongo abelii	98.06	3.00e-170	590.00
IUUC-Pca-101022	Procavia capensis	99.11	1.00e-65	243.00
IUUC-Ppe-101545	Prunus persica	43.45	6.00e-39	154.00
IUUC-Pva-102844	Pteropus vampyrus	94.74	0.00e+00	665.00
IUUC-Rno-104896	Rattus norvegicus	85.64	8.00e-175	605.00
IUUC-Sha-107106	Sarcophilus harrisii	84.55	2.00e-173	601.00
IUUC-Sit-110477	Setaria italica	43.86	2.00e-37	149.00
IUUC-Sly-111416	Solanum lycopersicum	39.13	4.00e-18	84.30
IUUC-Stu-112227	Solanum tuberosum	34.13	2.00e-20	92.00
IUUC-Sar-113534	Sorex araneus	80.68	3.00e-157	547.00
IUUC-Sbi-114751	Sorghum bicolor	42.77	4.00e-36	144.00
IUUC-Ssc-115274	Sus scrofa	93.07	0.00e+00	667.00
IUUC-Tgu-117426	Taeniopygia guttata	77.87	2.00e-145	508.00
IUUC-Tru-118059	Takifugu rubripes	74.74	9.00e-110	389.00
IUUC-Tsy-119448	Tarsius syrichta	83.66	1.00e-88	320.00
IUUC-Tni-120681	Tetraodon nigroviridis	89.15	4.00e-62	229.00
IUUC-Tca-121442	Theobroma cacao	35.83	1.00e-40	159.00
IUUC-Tae-123969	Triticum aestivum	42.11	7.00e-33	134.00
IUUC-Tbe-127638	Tupaia belangeri	88.98	4.00e-173	600.00
IUUC-Ttr-129288	Tursiops truncatus	83.93	5.00e-166	576.00
IUUC-Uma-129359	Ustilago maydis	38.22	3.00e-34	140.00
IUUC-Vda-129976	Verticillium dahliae	42.11	9.60e-01	29.60
IUUC-Vpa-130788	Vicugna pacos	93.56	0.00e+00	651.00
IUUC-Vvi-131227	Vitis vinifera	42.51	2.00e-36	145.00
IUUC-Xtr-132147	Xenopus tropicalis	68.56	8.00e-130	456.00
IUUC-Xma-133144	Xiphophorus maculatus	70.03	9.00e-110	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence