iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012898

Ensembl Protein ID

ENSBTAP00000008580.5

UniProt Accession

Q3SZC4; NSF1C_BOVIN

Genbank Protein ID

AAI02957.1

Protein Name

NSFL1 cofactor p47; p97 cofactor p47

Genbank Nucleotide ID

BC102956

Gene Name

NSFL1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000006533.5	ENSBTAT00000008580.5	ENSBTAP00000008580.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	4.20e-17	62.6	292	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++++qiRl+dG rlv+kF++s+++++i+ f+   +  +  + F L+++fP+++l++e++  tl+ea+L++  +++
   Q: 292  SQPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVdARPAMAATSFVLMTTFPNKELADENQ--TLKEANLLNAVIVQ 367
           6789*******************************9999***********************..*********99986 PP

Organism

Bos taurus

Functional Description
(View)

Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity).

Protein Sequence
(Fasta)

MAAERQDALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS 60
VSRGTAPSDN RVTSFRDLIH DQDEDEEEEE GQRFYAGGSE RSGQQIVGPP RKRSPNELVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGGGCGAA GATGGCGGCG GAGCGGCAGG ACGCTCTGAG GGAGTTCGTG GCGGTGACGG 60
GCGCAGAGGA GGATCGGGCC CGCTTCTTCC TGGAGTCGGC CGGCTGGGAC CTGCAGGTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0158--Chromosome
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0446--Lipid-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

SMART

SM00553--SEP
SM00166--UBX

Gene Ontology

GO:0005694--C:chromosome
GO:0005829--C:cytosol
GO:0005795--C:Golgi stack
GO:0045111--C:intermediate filament cytoskeleton
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0008289--F:lipid binding
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

bta:526612

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000550	Aegilops tauschii	37.45	9.00e-36	143.00
IUUC-Aml-001919	Ailuropoda melanoleuca	96.79	0.00e+00	713.00
IUUC-Atr-002543	Amborella trichopoda	30.73	1.00e-39	157.00
IUUC-Apl-003388	Anas platyrhynchos	87.11	0.00e+00	632.00
IUUC-Aca-005210	Anolis carolinensis	86.10	0.00e+00	642.00
IUUC-Aly-006329	Arabidopsis lyrata	34.64	1.00e-35	143.00
IUUC-Ago-007933	Ashbya gossypii	28.18	6.00e-19	88.60
IUUC-Acl-008176	Aspergillus clavatus	40.51	2.00e-30	126.00
IUUC-Afl-008553	Aspergillus flavus	37.11	6.00e-25	108.00
IUUC-Afu-008919	Aspergillus fumigatus	39.18	2.00e-29	123.00
IUUC-Ani-009398	Aspergillus nidulans	32.90	2.00e-40	159.00
IUUC-Ang-009594	Aspergillus niger	28.75	1.00e-31	130.00
IUUC-Aor-010016	Aspergillus oryzae	37.11	7.00e-25	108.00
IUUC-Ate-010455	Aspergillus terreus	35.89	6.00e-36	144.00
IUUC-Ame-011089	Astyanax mexicanus	72.04	1.00e-150	525.00
IUUC-Bci-013750	Botrytis cinerea	33.09	6.00e-30	124.00
IUUC-Bdi-014746	Brachypodium distachyon	35.71	1.00e-36	146.00
IUUC-Bol-015874	Brassica oleracea	29.61	4.00e-36	145.00
IUUC-Cel-018169	Caenorhabditis elegans	39.27	2.00e-38	152.00
IUUC-Cja-018993	Callithrix jacchus	96.51	0.00e+00	714.00
IUUC-Cfa-020958	Canis familiaris	98.11	0.00e+00	728.00
IUUC-Cpo-021417	Cavia porcellus	96.22	0.00e+00	712.00
IUUC-Csa-023244	Chlorocebus sabaeus	96.22	0.00e+00	717.00
IUUC-Cho-024335	Choloepus hoffmanni	74.52	3.00e-98	350.00
IUUC-Cin-025686	Ciona intestinalis	47.30	4.00e-91	328.00
IUUC-Csv-025945	Ciona savignyi	44.47	2.00e-86	312.00
IUUC-Cne-026798	Cryptococcus neoformans	38.42	9.00e-37	147.00
IUUC-Cme-027347	Cyanidioschyzon merolae	32.87	8.00e-29	120.00
IUUC-Dre-028748	Danio rerio	72.43	7.00e-149	520.00
IUUC-Dno-029977	Dasypus novemcinctus	96.51	0.00e+00	715.00
IUUC-Dor-030203	Dipodomys ordii	95.85	0.00e+00	641.00
IUUC-Dse-031256	Dothistroma septosporum	32.72	8.00e-32	130.00
IUUC-Dme-031878	Drosophila melanogaster	43.71	6.00e-60	224.00
IUUC-Ete-032997	Echinops telfairi	94.32	0.00e+00	699.00
IUUC-Eca-034132	Equus caballus	97.92	0.00e+00	660.00
IUUC-Eeu-035097	Erinaceus europaeus	72.94	7.00e-85	307.00
IUUC-Fca-036037	Felis catus	97.35	0.00e+00	657.00
IUUC-Fal-037100	Ficedula albicollis	86.17	2.00e-173	601.00
IUUC-Fso-038190	Fusarium solani	27.48	1.00e-30	127.00
IUUC-Gmo-039429	Gadus morhua	66.04	4.00e-131	461.00
IUUC-Gga-040864	Gallus gallus	88.04	0.00e+00	659.00
IUUC-Gac-041589	Gasterosteus aculeatus	70.51	5.00e-148	516.00
IUUC-Ggo-044601	Gorilla gorilla	96.24	0.00e+00	714.00
IUUC-Hsa-045773	Homo sapiens	96.76	0.00e+00	718.00
IUUC-Itr-047949	Ictidomys tridecemlineatus	97.31	0.00e+00	719.00
IUUC-Kpa-049322	Komagataella pastoris	32.37	3.00e-29	122.00
IUUC-Lch-050608	Latimeria chalumnae	73.78	6.00e-161	560.00
IUUC-Loc-052555	Lepisosteus oculatus	73.37	1.00e-157	548.00
IUUC-Laf-054237	Loxodonta africana	96.24	0.00e+00	716.00
IUUC-Mcc-055472	Macaca mulatta	95.97	0.00e+00	712.00
IUUC-Meu-056093	Macropus eugenii	72.15	2.00e-125	442.00
IUUC-Mor-057220	Magnaporthe oryzae	26.13	4.00e-29	122.00
IUUC-Mpo-057595	Magnaporthe poae	28.05	6.00e-20	91.70
IUUC-Mtr-058376	Medicago truncatula	36.27	3.00e-34	139.00
IUUC-Mla-059077	Melampsora laricipopulina	33.33	1.00e-35	144.00
IUUC-Mga-059836	Meleagris gallopavo	87.06	2.00e-173	601.00
IUUC-Mvi-060292	Microbotryum violaceum	38.74	2.00e-32	133.00
IUUC-Mmr-060897	Microcebus murinus	96.24	0.00e+00	712.00
IUUC-Mdo-062066	Monodelphis domestica	90.46	0.00e+00	679.00
IUUC-Mmu-063686	Mus musculus	96.77	0.00e+00	717.00
IUUC-Mac-065403	Musa acuminata	39.80	2.00e-33	137.00
IUUC-Mpu-065688	Mustela putorius furo	98.38	0.00e+00	730.00
IUUC-Mlu-067566	Myotis lucifugus	94.88	0.00e+00	684.00
IUUC-Nfi-068609	Neosartorya fischeri	33.45	4.00e-29	122.00
IUUC-Ncr-068786	Neurospora crassa	31.27	6.00e-25	108.00
IUUC-Nle-069169	Nomascus leucogenys	96.14	0.00e+00	651.00
IUUC-Opr-070979	Ochotona princeps	92.60	4.00e-177	613.00
IUUC-Ont-071803	Oreochromis niloticus	68.55	6.00e-145	506.00
IUUC-Ocu-074276	Oryctolagus cuniculus	95.96	0.00e+00	710.00
IUUC-Obr-076164	Oryza brachyantha	35.64	2.00e-27	115.00
IUUC-Olo-080254	Oryza longistaminata	39.78	3.00e-30	125.00
IUUC-Ome-081766	Oryza meridionalis	34.88	4.00e-31	130.00
IUUC-Opu-083365	Oryza punctata	34.40	5.00e-34	138.00
IUUC-Ola-086761	Oryzias latipes	68.82	6.00e-139	486.00
IUUC-Olu-087598	Ostreococcus lucimarinus	34.49	6.00e-33	134.00
IUUC-Oga-088533	Otolemur garnettii	96.76	0.00e+00	716.00
IUUC-Oar-089450	Ovis aries	99.73	0.00e+00	735.00
IUUC-Ptr-090926	Pan troglodytes	96.76	0.00e+00	718.00
IUUC-Pan-092100	Papio anubis	96.49	0.00e+00	716.00
IUUC-Psi-093446	Pelodiscus sinensis	85.46	1.00e-165	575.00
IUUC-Pma-094475	Petromyzon marinus	66.31	1.00e-104	372.00
IUUC-Pno-094769	Phaeosphaeria nodorum	32.42	3.00e-35	142.00
IUUC-Ppa-095833	Physcomitrella patens	34.97	8.00e-36	144.00
IUUC-Pfo-096193	Poecilia formosa	70.78	4.00e-150	524.00
IUUC-Pab-097971	Pongo abelii	96.76	0.00e+00	718.00
IUUC-Pop-098970	Populus trichocarpa	35.56	8.00e-43	167.00
IUUC-Pca-100390	Procavia capensis	94.98	5.00e-127	446.00
IUUC-Pva-102504	Pteropus vampyrus	88.98	0.00e+00	647.00
IUUC-Pgr-103447	Puccinia graminis	36.27	6.00e-34	138.00
IUUC-Ptt-103729	Puccinia triticina	33.23	3.00e-37	149.00
IUUC-Pte-104083	Pyrenophora teres	33.90	2.00e-39	156.00
IUUC-Pyt-104504	Pyrenophora triticirepentis	32.53	2.00e-35	143.00
IUUC-Rno-105448	Rattus norvegicus	97.57	0.00e+00	724.00
IUUC-Sce-106457	Saccharomyces cerevisiae	31.23	1.00e-29	124.00
IUUC-Sja-107717	Schizosaccharomyces japonicus	32.19	5.00e-30	125.00
IUUC-Spo-108358	Schizosaccharomyces pombe	29.25	2.00e-32	133.00
IUUC-Smo-109535	Selaginella moellendorffii	35.84	6.00e-33	134.00
IUUC-Sit-110328	Setaria italica	36.18	1.00e-34	140.00
IUUC-Sly-111135	Solanum lycopersicum	31.26	6.00e-41	161.00
IUUC-Stu-112733	Solanum tuberosum	34.25	1.00e-37	150.00
IUUC-Sar-113445	Sorex araneus	78.95	4.00e-129	453.00
IUUC-Sbi-114761	Sorghum bicolor	36.33	3.00e-34	139.00
IUUC-Sre-115176	Sporisorium reilianum	39.18	7.00e-31	128.00
IUUC-Ssc-116008	Sus scrofa	98.92	0.00e+00	731.00
IUUC-Tgu-117238	Taeniopygia guttata	87.23	0.00e+00	651.00
IUUC-Tru-118521	Takifugu rubripes	64.08	3.00e-136	478.00
IUUC-Tni-119705	Tetraodon nigroviridis	68.00	1.00e-140	492.00
IUUC-Tre-121941	Trichoderma reesei	35.34	2.00e-31	129.00
IUUC-Tvi-122602	Trichoderma virens	27.92	9.00e-29	120.00
IUUC-Tae-123686	Triticum aestivum	38.16	4.00e-38	151.00
IUUC-Tur-126267	Triticum urartu	38.31	4.00e-33	134.00
IUUC-Tme-127193	Tuber melanosporum	32.75	9.00e-39	154.00
IUUC-Tbe-127716	Tupaia belangeri	94.41	3.00e-162	563.00
IUUC-Ttr-128262	Tursiops truncatus	96.51	0.00e+00	711.00
IUUC-Uma-129600	Ustilago maydis	30.43	4.00e-41	162.00
IUUC-Vda-129743	Verticillium dahliae	30.38	6.00e-29	121.00
IUUC-Vpa-130068	Vicugna pacos	98.05	1.00e-172	598.00
IUUC-Xma-133944	Xiphophorus maculatus	70.24	5.00e-150	523.00
IUUC-Zma-135978	Zea mays	36.36	6.00e-35	141.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence