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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063806
Ensembl Protein ID ENSMUSP00000021832.6
UniProt Accession Q91XU0; Q3TCT7; Q6PDF0; Q8BUW5; Q8BWP6; Q8BY55; Q921W3; Q9EQL3; WRIP1_MOUSE
Genbank Protein ID BAB60708.1; BAC31091.1; BAC34213.1; BAC38404.1; BAE39633.1; BAE41868.1; BAE42069.1; CAI25647.1; AAH10482.1; AAH58744.1; AAG35725.1
Protein Name ATPase WRNIP1; Werner helicase-interacting protein 1
Genbank Nucleotide ID AB056151; AK041886; AK050368; AK082078; AK167570; AK170542; AK170846; AL645808; BC010482; BC058744; AF208046
Gene Name Wrnip1; Whip
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021400.6 ENSMUST00000021832.6 ENSMUSP00000021832.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDABioGRID
mUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/ZnF/UBZ 1.40e-08 35.9 17 40
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/ZnF/UBZ
   S: 1    llvCPvCqkmvdqtdfeeHlDeCl 24
           +++CPvCq+m++  ++++HlD+Cl
   Q: 17   QVQCPVCQQMMPAAHINSHLDRCL 40
           699********************8 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased.
 Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased.
Protein Sequence
(Fasta)
MEVSGPEDDP FLSQLHQVQC PVCQQMMPAA HINSHLDRCL LLHPAGHAEP AAGSHRAGER 60
AKGPSPPGAK RRRLSESSAL KQPATPTAAE SSEGEGEEGD DGGETESRES YDAPPTPSGA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063806|UBD,UBZ|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGAGGCGTTG CCAGCTGCGG GCCGAGGGCG AGTTGACGCG GGAGCTCAGG ACGTGAGGCA 60
TGAGCGGCGC CCTCCCTCGG CCCGTGCGTG TCCTGCTCCC TACCCGCGCG AGGGTCGCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063806|UBD,UBZ|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0235--DNA replication
KW-0378--Hydrolase
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003593--AAA+_ATPase
IPR032423--AAA_assoc_2
IPR003959--ATPase_AAA_core
IPR008921--DNA_pol3_clamp-load_cplx_C
IPR021886--MgsA_C
IPR027417--P-loop_NTPase
IPR006642--Znf_Rad18_put
Pfam

PF00004--AAA
PF16193--AAA_assoc_2
PF12002--MgsA_C
SMART

SM00382--AAA
SM00734--ZnF_Rad18
Gene Ontology

GO:0016020--C:membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003677--F:DNA binding
GO:0042802--F:identical protein binding
GO:0046872--F:metal ion binding
GO:0006260--P:DNA replication
GO:0000731--P:DNA synthesis involved in DNA repair
GO:0030174--P:regulation of DNA-dependent DNA replication initiation
KEGG mmu:78903
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002134 Ailuropoda melanoleuca 85.61 0.00e+00 1006.00
IUUC-Atr-002635 Amborella trichopoda 45.54 2.00e-116 413.00
IUUC-Apl-003962 Anas platyrhynchos 80.72 0.00e+00 741.00
IUUC-Aca-005219 Anolis carolinensis 80.34 8.00e-168 582.00
IUUC-Aly-005664 Arabidopsis lyrata 50.34 3.00e-120 425.00
IUUC-Ath-007605 Arabidopsis thaliana 49.89 4.00e-120 424.00
IUUC-Ago-007747 Ashbya gossypii 45.82 4.00e-103 368.00
IUUC-Acl-008260 Aspergillus clavatus 45.33 9.00e-102 363.00
IUUC-Afl-008493 Aspergillus flavus 45.96 7.00e-105 374.00
IUUC-Afu-008892 Aspergillus fumigatus 47.54 3.00e-105 375.00
IUUC-Ani-009289 Aspergillus nidulans 46.00 4.00e-104 372.00
IUUC-Ang-009599 Aspergillus niger 46.22 1.00e-102 367.00
IUUC-Aor-009987 Aspergillus oryzae 45.96 6.00e-105 374.00
IUUC-Ate-010577 Aspergillus terreus 47.14 4.00e-105 375.00
IUUC-Ame-010756 Astyanax mexicanus 44.94 6.00e-101 361.00
IUUC-Bgr-012158 Blumeria graminis 46.28 3.00e-101 362.00
IUUC-Bta-013537 Bos taurus 89.33 0.00e+00 842.00
IUUC-Bci-013965 Botrytis cinerea 46.47 2.00e-106 379.00
IUUC-Bol-015473 Brassica oleracea 50.34 2.00e-116 412.00
IUUC-Bra-017208 Brassica rapa 48.40 5.00e-112 398.00
IUUC-Cja-019193 Callithrix jacchus 96.95 0.00e+00 913.00
IUUC-Cfa-020149 Canis familiaris 96.88 0.00e+00 885.00
IUUC-Cpo-021486 Cavia porcellus 97.82 0.00e+00 911.00
IUUC-Csa-024006 Chlorocebus sabaeus 94.29 0.00e+00 1121.00
IUUC-Cho-024632 Choloepus hoffmanni 88.24 0.00e+00 674.00
IUUC-Cne-026982 Cryptococcus neoformans 45.71 2.00e-82 299.00
IUUC-Dre-027822 Danio rerio 72.31 0.00e+00 652.00
IUUC-Dno-029727 Dasypus novemcinctus 96.00 0.00e+00 873.00
IUUC-Dor-030227 Dipodomys ordii 95.14 0.00e+00 740.00
IUUC-Dse-031247 Dothistroma septosporum 45.73 1.00e-100 360.00
IUUC-Ete-033089 Echinops telfairi 90.65 0.00e+00 969.00
IUUC-Eca-033998 Equus caballus 97.44 0.00e+00 772.00
IUUC-Eeu-035147 Erinaceus europaeus 96.94 0.00e+00 903.00
IUUC-Fca-036247 Felis catus 97.70 0.00e+00 772.00
IUUC-Fal-037605 Ficedula albicollis 79.73 1.00e-178 618.00
IUUC-Fox-038016 Fusarium oxysporum 47.15 3.00e-93 335.00
IUUC-Fso-038200 Fusarium solani 44.89 1.00e-96 347.00
IUUC-Gmo-039155 Gadus morhua 67.28 8.00e-170 590.00
IUUC-Ggr-040037 Gaeumannomyces graminis 48.08 2.00e-104 372.00
IUUC-Gga-041277 Gallus gallus 79.91 0.00e+00 738.00
IUUC-Gac-042576 Gasterosteus aculeatus 70.26 0.00e+00 660.00
IUUC-Gma-043574 Glycine max 48.67 7.00e-116 410.00
IUUC-Ggo-045359 Gorilla gorilla 93.96 0.00e+00 905.00
IUUC-Hsa-045689 Homo sapiens 93.98 0.00e+00 1103.00
IUUC-Itr-048239 Ictidomys tridecemlineatus 98.04 0.00e+00 910.00
IUUC-Kpa-049277 Komagataella pastoris 43.64 3.00e-97 349.00
IUUC-Lch-049430 Latimeria chalumnae 74.11 8.00e-85 306.00
IUUC-Loc-052461 Lepisosteus oculatus 73.29 0.00e+00 678.00
IUUC-Lma-053060 Leptosphaeria maculans 43.30 2.00e-99 356.00
IUUC-Laf-053418 Loxodonta africana 95.86 0.00e+00 917.00
IUUC-Mcc-055094 Macaca mulatta 94.44 0.00e+00 1106.00
IUUC-Meu-056838 Macropus eugenii 65.89 4.00e-174 604.00
IUUC-Mor-057036 Magnaporthe oryzae 47.61 1.00e-100 360.00
IUUC-Mtr-057969 Medicago truncatula 48.76 3.00e-118 418.00
IUUC-Mla-059065 Melampsora laricipopulina 39.82 5.00e-82 298.00
IUUC-Mga-059360 Meleagris gallopavo 78.91 0.00e+00 682.00
IUUC-Mmr-060962 Microcebus murinus 97.17 0.00e+00 911.00
IUUC-Mdo-062007 Monodelphis domestica 72.26 0.00e+00 907.00
IUUC-Mac-064594 Musa acuminata 43.78 3.00e-37 149.00
IUUC-Mpu-066476 Mustela putorius furo 97.39 0.00e+00 928.00
IUUC-Mlu-067439 Myotis lucifugus 93.24 0.00e+00 785.00
IUUC-Nfi-068391 Neosartorya fischeri 46.88 5.00e-104 371.00
IUUC-Ncr-068746 Neurospora crassa 46.47 5.00e-95 342.00
IUUC-Nle-069387 Nomascus leucogenys 93.89 0.00e+00 1049.00
IUUC-Opr-070903 Ochotona princeps 75.06 4.00e-120 425.00
IUUC-Ont-071546 Oreochromis niloticus 70.81 0.00e+00 662.00
IUUC-Oan-073696 Ornithorhynchus anatinus 79.66 1.00e-165 575.00
IUUC-Ocu-074768 Oryctolagus cuniculus 97.14 0.00e+00 881.00
IUUC-Oin-079459 Oryza indica 42.76 2.00e-75 277.00
IUUC-Ola-087403 Oryzias latipes 72.89 0.00e+00 665.00
IUUC-Oga-088904 Otolemur garnettii 93.52 0.00e+00 1112.00
IUUC-Oar-089703 Ovis aries 88.03 5.00e-116 409.00
IUUC-Ptr-090666 Pan troglodytes 93.53 0.00e+00 1064.00
IUUC-Pan-092020 Papio anubis 97.19 0.00e+00 782.00
IUUC-Psi-092949 Pelodiscus sinensis 79.96 0.00e+00 752.00
IUUC-Pma-094432 Petromyzon marinus 58.61 9.00e-117 413.00
IUUC-Pno-095095 Phaeosphaeria nodorum 44.97 5.00e-106 378.00
IUUC-Ppa-095376 Physcomitrella patens 60.43 1.00e-63 238.00
IUUC-Pfo-096882 Poecilia formosa 75.74 0.00e+00 691.00
IUUC-Pab-098159 Pongo abelii 94.38 0.00e+00 907.00
IUUC-Pop-098867 Populus trichocarpa 51.71 3.00e-123 435.00
IUUC-Pca-100549 Procavia capensis 90.81 0.00e+00 1094.00
IUUC-Pva-102427 Pteropus vampyrus 92.91 0.00e+00 1050.00
IUUC-Pgr-103584 Puccinia graminis 39.27 5.00e-89 322.00
IUUC-Ptt-103965 Puccinia triticina 42.24 5.00e-54 204.00
IUUC-Pte-104110 Pyrenophora teres 46.09 4.00e-104 371.00
IUUC-Pyt-104578 Pyrenophora triticirepentis 44.32 9.00e-104 370.00
IUUC-Rno-106096 Rattus norvegicus 98.79 0.00e+00 1138.00
IUUC-Sce-106299 Saccharomyces cerevisiae 46.24 5.00e-104 371.00
IUUC-Sha-106678 Sarcophilus harrisii 86.37 0.00e+00 812.00
IUUC-Sja-107709 Schizosaccharomyces japonicus 46.47 2.00e-104 372.00
IUUC-Spo-108286 Schizosaccharomyces pombe 46.92 3.00e-110 392.00
IUUC-Smo-109453 Selaginella moellendorffii 54.36 1.00e-122 433.00
IUUC-Sly-111329 Solanum lycopersicum 47.86 4.00e-120 425.00
IUUC-Stu-112498 Solanum tuberosum 48.29 3.00e-122 432.00
IUUC-Sre-115000 Sporisorium reilianum 44.54 9.00e-103 367.00
IUUC-Ssc-115336 Sus scrofa 92.89 0.00e+00 855.00
IUUC-Tgu-116596 Taeniopygia guttata 78.22 0.00e+00 731.00
IUUC-Tru-117850 Takifugu rubripes 73.70 0.00e+00 680.00
IUUC-Tsy-118903 Tarsius syrichta 97.86 0.00e+00 645.00
IUUC-Tni-120817 Tetraodon nigroviridis 72.73 0.00e+00 663.00
IUUC-Tca-121843 Theobroma cacao 48.29 2.00e-122 432.00
IUUC-Tre-121913 Trichoderma reesei 46.27 2.00e-96 346.00
IUUC-Tvi-122613 Trichoderma virens 47.62 2.00e-97 350.00
IUUC-Tme-127063 Tuber melanosporum 46.19 2.00e-97 348.00
IUUC-Tbe-127342 Tupaia belangeri 83.63 0.00e+00 630.00
IUUC-Ttr-128381 Tursiops truncatus 92.07 0.00e+00 754.00
IUUC-Uma-129504 Ustilago maydis 43.62 1.00e-103 370.00
IUUC-Vda-129930 Verticillium dahliae 45.27 1.00e-96 347.00
IUUC-Vvi-130851 Vitis vinifera 50.33 5.00e-121 427.00
IUUC-Xtr-131772 Xenopus tropicalis 66.78 5.00e-102 364.00
IUUC-Xma-133802 Xiphophorus maculatus 75.74 0.00e+00 692.00
IUUC-Yli-134331 Yarrowia lipolytica 52.38 2.00e-54 206.00
Created Date 25-Jun-2017

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