iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054031

UUCD1 version

UUC-LoA-00695

Ensembl Protein ID

ENSLAFP00000017836.2

UniProt Accession

G3TQK2; G3TQK2_LOXAF

Protein Name

Uncharacterized protein

Gene Name

FBXL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000022751.2	ENSLAFT00000023106.2	ENSLAFP00000017836.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	8.80e-06	26.2	202	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 100  aglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            +++++lp e++++i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 202  CTSINHLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 248
           567899*********************************9****987 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAPFPEEVDV FTAPHWRMKQ LVGLYCDKLS KTNFSNNNDF RALLQSLYAT FKEFKMHEQI 60
ENEYIIGLLQ QRSQTIYNVH SDNKLSEMLS LFEKGLKNVK NEYEQLNYAK QLKERLEAFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCCCT TCCCCGAGGA AGTGGACGTC TTTACCGCTC CGCACTGGCG GATGAAGCAG 60
CTGGTGGGAC TCTACTGCGA CAAGGTAACG GTGTGCGGAG GCCTCTAGCT CCGGGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR012312--Haemerythrin-like
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF01814--Hemerythrin
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

lav:100675379

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	95.37	0.00e+00	1194.00
IUUC-Apl-003755	Anas platyrhynchos	80.72	0.00e+00	1013.00
IUUC-Aca-004798	Anolis carolinensis	77.78	0.00e+00	1046.00
IUUC-Ame-011091	Astyanax mexicanus	60.00	0.00e+00	771.00
IUUC-Bta-013204	Bos taurus	92.96	0.00e+00	1193.00
IUUC-Cja-019594	Callithrix jacchus	94.51	0.00e+00	1036.00
IUUC-Cfa-020965	Canis familiaris	95.37	0.00e+00	1236.00
IUUC-Cpo-021308	Cavia porcellus	92.62	0.00e+00	1236.00
IUUC-Csa-023865	Chlorocebus sabaeus	95.22	0.00e+00	1300.00
IUUC-Cho-024778	Choloepus hoffmanni	83.24	4.00e-165	574.00
IUUC-Dre-027628	Danio rerio	55.65	3.00e-178	618.00
IUUC-Dno-029899	Dasypus novemcinctus	94.90	0.00e+00	1304.00
IUUC-Dor-031105	Dipodomys ordii	80.27	0.00e+00	1049.00
IUUC-Ete-032314	Echinops telfairi	88.24	0.00e+00	1098.00
IUUC-Eca-033797	Equus caballus	94.65	0.00e+00	1142.00
IUUC-Eeu-034811	Erinaceus europaeus	83.63	0.00e+00	881.00
IUUC-Fca-036516	Felis catus	94.73	0.00e+00	1172.00
IUUC-Fal-036824	Ficedula albicollis	78.34	0.00e+00	941.00
IUUC-Gga-040271	Gallus gallus	81.07	0.00e+00	1077.00
IUUC-Gac-041399	Gasterosteus aculeatus	61.48	0.00e+00	793.00
IUUC-Ggo-044415	Gorilla gorilla	95.37	0.00e+00	1302.00
IUUC-Hsa-047001	Homo sapiens	95.37	0.00e+00	1328.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	93.07	0.00e+00	1045.00
IUUC-Lch-049897	Latimeria chalumnae	66.48	0.00e+00	837.00
IUUC-Loc-052162	Lepisosteus oculatus	66.95	0.00e+00	866.00
IUUC-Mcc-054680	Macaca mulatta	95.22	0.00e+00	1300.00
IUUC-Meu-056199	Macropus eugenii	83.70	5.00e-106	378.00
IUUC-Mga-059675	Meleagris gallopavo	80.45	0.00e+00	1028.00
IUUC-Mmr-061694	Microcebus murinus	94.93	0.00e+00	1302.00
IUUC-Mdo-062900	Monodelphis domestica	90.30	0.00e+00	1239.00
IUUC-Mmu-063178	Mus musculus	91.90	0.00e+00	1253.00
IUUC-Mpu-066584	Mustela putorius furo	95.37	0.00e+00	1249.00
IUUC-Mlu-067859	Myotis lucifugus	93.98	0.00e+00	1184.00
IUUC-Nle-069172	Nomascus leucogenys	95.95	0.00e+00	1279.00
IUUC-Opr-070992	Ochotona princeps	90.80	0.00e+00	1019.00
IUUC-Ont-072577	Oreochromis niloticus	61.42	0.00e+00	798.00
IUUC-Oan-072870	Ornithorhynchus anatinus	85.05	0.00e+00	918.00
IUUC-Ocu-074849	Oryctolagus cuniculus	91.90	0.00e+00	1241.00
IUUC-Ola-087146	Oryzias latipes	60.87	0.00e+00	786.00
IUUC-Oga-088307	Otolemur garnettii	94.61	0.00e+00	1236.00
IUUC-Oar-090192	Ovis aries	91.18	0.00e+00	1206.00
IUUC-Ptr-091049	Pan troglodytes	95.66	0.00e+00	1305.00
IUUC-Pan-091995	Papio anubis	95.37	0.00e+00	1302.00
IUUC-Psi-093154	Pelodiscus sinensis	80.22	0.00e+00	998.00
IUUC-Pma-094334	Petromyzon marinus	46.04	5.00e-141	494.00
IUUC-Pfo-096154	Poecilia formosa	60.53	0.00e+00	774.00
IUUC-Pab-098264	Pongo abelii	95.48	0.00e+00	1245.00
IUUC-Pca-100884	Procavia capensis	82.07	0.00e+00	671.00
IUUC-Pva-102114	Pteropus vampyrus	94.51	0.00e+00	1283.00
IUUC-Rno-105392	Rattus norvegicus	92.76	0.00e+00	1259.00
IUUC-Sha-106508	Sarcophilus harrisii	87.08	0.00e+00	1174.00
IUUC-Sar-113107	Sorex araneus	90.14	0.00e+00	834.00
IUUC-Ssc-115489	Sus scrofa	95.37	0.00e+00	1235.00
IUUC-Tgu-116734	Taeniopygia guttata	79.36	0.00e+00	1029.00
IUUC-Tru-117632	Takifugu rubripes	61.39	0.00e+00	781.00
IUUC-Tsy-119400	Tarsius syrichta	93.97	0.00e+00	1193.00
IUUC-Tni-120602	Tetraodon nigroviridis	60.50	0.00e+00	793.00
IUUC-Tbe-127833	Tupaia belangeri	92.73	0.00e+00	645.00
IUUC-Ttr-129289	Tursiops truncatus	94.48	0.00e+00	751.00
IUUC-Vpa-130253	Vicugna pacos	94.48	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence