iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107074

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01023080

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007964.1	ENSSHAT00000009278.1	ENSSHAP00000009199.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-10	38.9	98	127

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           Htd v  l+f ++  l++s+s D+t+k+W+
   Q: 98   HTDQVLHLSFsHTgYLFASCSKDCTVKIWN 127
           9*********8555889************9 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

PWGQNDTMDD GGNPFLPDSI IYQIFLSLSH EDVLAAGLVC RQWQAVSRDE FLWKELFYRY 60
YQVARDVPRH PAAVSWYEEF QRLYDTIPCV EVQTLREHTD QVLHLSFSHT GYLFASCSKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTGGGGAC AGAATGACAC GATGGATGAT GGGGGCAACC CCTTCCTTCC AGACAGTATT 60
ATTTACCAGA TCTTCTTGAG CCTGAGCCAT GAAGATGTGC TAGCTGCAGG GTTGGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001810--F-box_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	81.25	0.00e+00	908.00
IUUC-Apl-003274	Anas platyrhynchos	81.00	0.00e+00	800.00
IUUC-Aca-004626	Anolis carolinensis	57.01	5.00e-99	353.00
IUUC-Ame-011823	Astyanax mexicanus	62.92	0.00e+00	629.00
IUUC-Bta-012523	Bos taurus	81.25	0.00e+00	897.00
IUUC-Bdi-014933	Brachypodium distachyon	31.48	4.00e-06	44.70
IUUC-Cja-018729	Callithrix jacchus	83.27	0.00e+00	936.00
IUUC-Cfa-020303	Canis familiaris	83.79	0.00e+00	926.00
IUUC-Cpo-022134	Cavia porcellus	82.63	0.00e+00	926.00
IUUC-Csa-023253	Chlorocebus sabaeus	83.82	0.00e+00	944.00
IUUC-Cin-025742	Ciona intestinalis	34.11	8.00e-77	281.00
IUUC-Dre-027511	Danio rerio	68.21	0.00e+00	737.00
IUUC-Dno-029044	Dasypus novemcinctus	81.47	0.00e+00	919.00
IUUC-Dor-030565	Dipodomys ordii	82.54	0.00e+00	915.00
IUUC-Dme-031713	Drosophila melanogaster	42.64	4.00e-130	458.00
IUUC-Eca-033709	Equus caballus	82.54	0.00e+00	902.00
IUUC-Eeu-035093	Erinaceus europaeus	86.74	1.00e-94	340.00
IUUC-Fca-035674	Felis catus	82.42	0.00e+00	900.00
IUUC-Fal-037104	Ficedula albicollis	78.12	0.00e+00	865.00
IUUC-Gmo-039041	Gadus morhua	63.41	0.00e+00	655.00
IUUC-Gga-041230	Gallus gallus	77.51	0.00e+00	895.00
IUUC-Gac-042594	Gasterosteus aculeatus	63.78	0.00e+00	663.00
IUUC-Ggo-044486	Gorilla gorilla	83.46	0.00e+00	911.00
IUUC-Hsa-045701	Homo sapiens	83.64	0.00e+00	913.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	82.54	0.00e+00	927.00
IUUC-Lch-050058	Latimeria chalumnae	72.48	0.00e+00	852.00
IUUC-Loc-052525	Lepisosteus oculatus	71.71	0.00e+00	754.00
IUUC-Laf-054120	Loxodonta africana	83.06	0.00e+00	944.00
IUUC-Mcc-054915	Macaca mulatta	83.82	0.00e+00	944.00
IUUC-Meu-056715	Macropus eugenii	86.44	0.00e+00	961.00
IUUC-Mga-059831	Meleagris gallopavo	77.99	0.00e+00	796.00
IUUC-Mvi-060236	Microbotryum violaceum	32.39	3.00e-05	44.30
IUUC-Mmr-060655	Microcebus murinus	82.54	0.00e+00	927.00
IUUC-Mdo-062641	Monodelphis domestica	92.64	0.00e+00	1056.00
IUUC-Mmu-063471	Mus musculus	82.72	0.00e+00	927.00
IUUC-Mpu-066586	Mustela putorius furo	84.19	0.00e+00	916.00
IUUC-Nle-069429	Nomascus leucogenys	83.27	0.00e+00	939.00
IUUC-Ont-071780	Oreochromis niloticus	68.24	0.00e+00	720.00
IUUC-Ola-086458	Oryzias latipes	68.32	0.00e+00	731.00
IUUC-Oga-088739	Otolemur garnettii	81.43	0.00e+00	921.00
IUUC-Oar-089275	Ovis aries	87.21	1.00e-44	170.00
IUUC-Ptr-090716	Pan troglodytes	81.94	0.00e+00	736.00
IUUC-Pan-092182	Papio anubis	76.10	0.00e+00	828.00
IUUC-Psi-093449	Pelodiscus sinensis	78.52	0.00e+00	893.00
IUUC-Pma-094289	Petromyzon marinus	53.28	7.00e-170	590.00
IUUC-Pfo-096062	Poecilia formosa	68.01	0.00e+00	727.00
IUUC-Pab-098726	Pongo abelii	79.13	0.00e+00	919.00
IUUC-Pca-100163	Procavia capensis	83.60	5.00e-93	334.00
IUUC-Pva-103051	Pteropus vampyrus	82.20	4.00e-114	404.00
IUUC-Rno-105707	Rattus norvegicus	82.17	0.00e+00	907.00
IUUC-Ssc-116020	Sus scrofa	80.36	0.00e+00	790.00
IUUC-Tgu-116683	Taeniopygia guttata	73.85	2.00e-106	378.00
IUUC-Tru-118143	Takifugu rubripes	67.54	0.00e+00	707.00
IUUC-Tni-120777	Tetraodon nigroviridis	66.78	0.00e+00	717.00
IUUC-Ttr-128439	Tursiops truncatus	80.51	0.00e+00	886.00
IUUC-Xtr-132774	Xenopus tropicalis	57.89	9.00e-148	516.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence