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Tag Content
UUCD2 ID IUUC-Cfa-020761
UUCD1 version UUC-CaF-00983
Ensembl Protein ID ENSCAFP00000029601.3
UniProt Accession F1PD56; F1PD56_CANLF
Genbank Protein ID ENSCAFP00000029601
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAEX03006844
Gene Name USP20
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000019975.3 ENSCAFT00000031793.3 ENSCAFP00000029601.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.80e-109 366.3 145 685
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tG+kNlgN+CYmN++LQ+Lsn+p+l++++le     +    ++++k +l+ks+qkl++e+w  ++ ++v p++l + +k ++++f+gy+
   Q: 145  TGMKNLGNSCYMNAALQALSNCPPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVSEVWhRRRPSYVVPTSLSHGIKLVNPMFRGYA 228
           7******************************.....999999*******************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkk..............eknkpkeeeeeedkselsde.................................. 129
           qqD+qEfl++l+dql+eelk+              +++++++e++e d+s ++de                                  
   Q: 229  QQDTQEFLCCLMDQLHEELKEpvvaaaaalvetrdSDSSDTDEKREGDRSPSEDEflscdsssdrgegdgqgrggggsqaeaellipde 317
           *******************998886666666655555555555555555555555********************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 318  agraisekermkdrkfswgqqrtsseqvdedadvdtamaalddqpseaqppslqspspcrtpepdneahmwstsrpcspvhhheghtkl 406
           ***************************************************************************************** PP
   S: 130  ...........................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke...... 185
                                      ++++k+++++s+isd+F+g++ s ++cl+cd+vs++ e+f+dlslp+pgke+ + +      
   Q: 407  assppraspvrmgpsyvlkkaqvlsagSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLARLhsaiyq 495
           ******************************************************************************98888****** PP
   S: 186  ...........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLi 231
                                                      +l+dcL++f+ ++el+g+n+y+ce+ckk+++ +k +k+ +lPe+L 
   Q: 496  napakpgacgdsyaaqgwlafimeyirrflvsctpswfwgpvvTLEDCLAAFFVADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILY 584
           ***************************************************************************************** PP
   S: 232  lhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevk 318
           +hLkRf  ++e + + ki+++v+fple Ldl+pf+++++++q   ++Y+L++v++H+G+++sGHY+ay++n  +g+W++fdD++Vtev+
   Q: 585  IHLKRF--RHEVMYSFKISSHVSFPLEgLDLRPFLAKECTSQ--ITTYDLLSVICHHGTAGSGHYIAYCQNvINGQWYEFDDQYVTEVH 669
           ******..9999***************************999..9**************************78999************* PP
   S: 319  eeevleetgstaYvlfYkr 337
           e+ v++   ++aYvlfY++
   Q: 670  ETVVQS---AEAYVLFYRK 685
           ******...********98 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MGDSRDFCPH LDSIGEVTKE DLLFKSKGAC QSCGVTGPNL WACLQVACPY VGCGESFADH 60
STIHAQAKKH NLTVNLTTFR VWCYACEKEV FLEQRLAAHP AGPSPRFSEQ DSPLPSHPLK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020761|DUB,USP|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGATGGTGT TCAGTTGCTG CTCACAATAG CTGATACCCC AGGATTTGGA GATACAGCCC 60
ATAATGTAAT TGCTGGCAGC CTGTTTTTGA CCACATTGCT AGTAAATTTG AAGACTAAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020761|DUB,USP|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cfa:480696
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002209 Ailuropoda melanoleuca 95.19 0.00e+00 1708.00
IUUC-Apl-003351 Anas platyrhynchos 84.67 0.00e+00 1563.00
IUUC-Aca-005077 Anolis carolinensis 75.20 0.00e+00 1102.00
IUUC-Ame-011777 Astyanax mexicanus 74.92 0.00e+00 1328.00
IUUC-Bta-013063 Bos taurus 93.88 0.00e+00 1662.00
IUUC-Cja-019868 Callithrix jacchus 92.47 0.00e+00 1696.00
IUUC-Cpo-022267 Cavia porcellus 84.95 0.00e+00 1528.00
IUUC-Csa-024251 Chlorocebus sabaeus 93.66 0.00e+00 1710.00
IUUC-Cho-024483 Choloepus hoffmanni 95.75 2.00e-122 432.00
IUUC-Csv-025889 Ciona savignyi 43.75 2.00e-35 141.00
IUUC-Dre-028061 Danio rerio 73.82 0.00e+00 1203.00
IUUC-Dno-029423 Dasypus novemcinctus 94.10 0.00e+00 1693.00
IUUC-Dor-030877 Dipodomys ordii 90.00 0.00e+00 1078.00
IUUC-Dme-031837 Drosophila melanogaster 49.45 6.00e-137 481.00
IUUC-Ete-032802 Echinops telfairi 80.34 4.00e-136 478.00
IUUC-Eca-034283 Equus caballus 93.55 0.00e+00 1687.00
IUUC-Eeu-034620 Erinaceus europaeus 90.79 0.00e+00 1181.00
IUUC-Fca-036357 Felis catus 95.74 0.00e+00 1697.00
IUUC-Fal-037411 Ficedula albicollis 85.42 0.00e+00 1563.00
IUUC-Gga-041101 Gallus gallus 84.70 0.00e+00 1540.00
IUUC-Gac-041315 Gasterosteus aculeatus 73.45 0.00e+00 1310.00
IUUC-Ggo-045600 Gorilla gorilla 93.37 0.00e+00 1662.00
IUUC-Hsa-045825 Homo sapiens 93.99 0.00e+00 1675.00
IUUC-Itr-048549 Ictidomys tridecemlineatus 80.53 0.00e+00 1388.00
IUUC-Lch-050002 Latimeria chalumnae 74.49 0.00e+00 1307.00
IUUC-Loc-052574 Lepisosteus oculatus 77.04 0.00e+00 1400.00
IUUC-Laf-054428 Loxodonta africana 92.15 0.00e+00 1656.00
IUUC-Mcc-055736 Macaca mulatta 93.66 0.00e+00 1707.00
IUUC-Mga-059781 Meleagris gallopavo 84.16 0.00e+00 1541.00
IUUC-Mdo-063048 Monodelphis domestica 87.69 0.00e+00 1528.00
IUUC-Mmu-064079 Mus musculus 90.72 0.00e+00 1630.00
IUUC-Mpu-066616 Mustela putorius furo 94.00 0.00e+00 1743.00
IUUC-Mlu-067294 Myotis lucifugus 92.46 0.00e+00 1609.00
IUUC-Nle-070015 Nomascus leucogenys 93.44 0.00e+00 1634.00
IUUC-Opr-070328 Ochotona princeps 92.15 0.00e+00 1664.00
IUUC-Ont-071464 Oreochromis niloticus 73.88 0.00e+00 1299.00
IUUC-Oan-073259 Ornithorhynchus anatinus 78.79 0.00e+00 1310.00
IUUC-Ocu-074630 Oryctolagus cuniculus 89.73 0.00e+00 1585.00
IUUC-Ola-087240 Oryzias latipes 73.35 0.00e+00 1283.00
IUUC-Oga-088761 Otolemur garnettii 92.24 0.00e+00 1682.00
IUUC-Oar-089490 Ovis aries 88.74 0.00e+00 1506.00
IUUC-Ptr-091662 Pan troglodytes 94.10 0.00e+00 1675.00
IUUC-Pan-092199 Papio anubis 93.24 0.00e+00 1699.00
IUUC-Psi-093726 Pelodiscus sinensis 85.61 0.00e+00 1557.00
IUUC-Pma-094389 Petromyzon marinus 63.76 3.00e-98 351.00
IUUC-Pab-098632 Pongo abelii 93.77 0.00e+00 1667.00
IUUC-Pca-100614 Procavia capensis 85.38 0.00e+00 1285.00
IUUC-Pva-102922 Pteropus vampyrus 91.05 0.00e+00 970.00
IUUC-Rno-105215 Rattus norvegicus 90.38 0.00e+00 1626.00
IUUC-Sce-106176 Saccharomyces cerevisiae 32.97 6.00e-26 112.00
IUUC-Sha-106601 Sarcophilus harrisii 85.62 0.00e+00 1508.00
IUUC-Ssc-115533 Sus scrofa 91.90 0.00e+00 1635.00
IUUC-Tgu-117364 Taeniopygia guttata 85.26 0.00e+00 1525.00
IUUC-Tru-117770 Takifugu rubripes 71.31 0.00e+00 1275.00
IUUC-Tni-120001 Tetraodon nigroviridis 72.64 0.00e+00 1252.00
IUUC-Ttr-128732 Tursiops truncatus 94.32 0.00e+00 1682.00
IUUC-Xtr-132157 Xenopus tropicalis 76.04 0.00e+00 1354.00
Created Date 25-Jun-2017

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