iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.30e-16	58.8	48	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.90e-06	26.6	149	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmele.esksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v++ +f+ah++vLaasS++F a+f      es+ k+++++ ++++ ++  +++++Yt+ l++n
   Q: 48   TDVTLIVEEHRFKAHRVVLAASSDYFCAMFADCAMiESR-KDEINLYGIKARAMGSIIDYIYTSMLELN 115
           7*****************************665556**9.***********************999876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eNcl+i  +Ad+y+  dL ++a ++++ hF+
   Q: 149  ENCLAIAGMADIYGIMDLSERAYRYMCAHFE 179
           8*****************************5 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MAATPAPAVT PAATATSAAA KIPVNPVSPE EETLLRGLNK LRNEEKLTDV TLIVEEHRFK 60
AHRVVLAASS DYFCAMFADC AMIESRKDEI NLYGIKARAM GSIIDYIYTS MLELNYDNIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACGCGAAAA GTAAAAAGTC GCAAGAGGGA AAAGAAGCAA AGAGGTAGCA ACAAGCAAAG 60
AAATCGCACG CGAAACTTTT TTCTCTGCCA GTGTTTAGCA ATAATTTAGC TAATTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0051301--P:cell division
GO:0016567--P:protein ubiquitination

KEGG

dme:Dmel_CG1812

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005015	Anolis carolinensis	29.00	9.00e-55	207.00
IUUC-Psi-093484	Pelodiscus sinensis	28.73	1.00e-56	213.00
IUUC-Pma-094224	Petromyzon marinus	28.57	2.00e-58	219.00
IUUC-Pte-104106	Pyrenophora teres	30.77	1.00e-07	49.30
IUUC-Pyt-104515	Pyrenophora triticirepentis	30.26	5.00e-06	43.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence