iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-094039

Ensembl Protein ID

ENSPSIP00000008058.1

UniProt Accession

K7FJ48; K7FJ48_PELSI

Genbank Protein ID

ENSPSIP00000008058

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01151939

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000007384.1	ENSPSIT00000008100.1	ENSPSIP00000008058.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	29.17	7.00e-03	37.00	IUUC-Dme-031988
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	67.38	3.00e-51	198.00	IUUC-Hsa-046547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LSPVSGGWRV GSEMPQEPGE EGREQRRLLR SVNTRELSHV IFCNRAQLQP YAVLQPGTGR 60
RMHSYLEHLW LFRDAETDDG LLVNQTEMFV PTHNINGQPV FANITLPVFS LKERCLQVVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTCCCCGG TCAGTGGCGG TTGGCGCGTC GGTTCGGAGA TGCCCCAGGA GCCGGGGGAG 60
GAAGGGCGGG AGCAGCGGCG GCTCCTGCGC TCTGTCAACA CGCGGGAGCT CTCTCACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

Pfam

PF01847--VHL
PF17211--VHL_C

Gene Ontology

GO:0005929--C:cilium
GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0001525--P:angiogenesis
GO:0043534--P:blood vessel endothelial cell migration
GO:0061073--P:ciliary body morphogenesis
GO:0030198--P:extracellular matrix organization
GO:0048069--P:eye pigmentation
GO:0048877--P:homeostasis of number of retina cells
GO:0061072--P:iris morphogenesis
GO:0006582--P:melanin metabolic process
GO:0045602--P:negative regulation of endothelial cell differentiation
GO:0010629--P:negative regulation of gene expression
GO:1902072--P:negative regulation of hypoxia-inducible factor-1alpha signaling pathway
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0003310--P:pancreatic A cell differentiation
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0010498--P:proteasomal protein catabolic process
GO:2001233--P:regulation of apoptotic signaling pathway
GO:1903827--P:regulation of cellular protein localization
GO:0003309--P:type B pancreatic cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002327	Ailuropoda melanoleuca	56.71	3.00e-44	171.00
IUUC-Apl-003580	Anas platyrhynchos	73.81	2.00e-29	119.00
IUUC-Aca-004492	Anolis carolinensis	66.67	3.00e-48	183.00
IUUC-Ame-011818	Astyanax mexicanus	49.03	6.00e-37	146.00
IUUC-Bta-013459	Bos taurus	67.55	2.00e-53	201.00
IUUC-Cja-019826	Callithrix jacchus	65.16	6.00e-52	196.00
IUUC-Cfa-021280	Canis familiaris	61.25	2.00e-51	194.00
IUUC-Cpo-022544	Cavia porcellus	61.96	9.00e-53	199.00
IUUC-Cre-022809	Chlamydomonas reinhardtii	42.86	1.70e-01	30.40
IUUC-Csa-023644	Chlorocebus sabaeus	67.13	4.00e-52	196.00
IUUC-Cho-024479	Choloepus hoffmanni	44.95	9.00e-20	88.60
IUUC-Cme-027232	Cyanidioschyzon merolae	25.51	4.00e-03	34.70
IUUC-Dre-028350	Danio rerio	45.16	3.00e-24	103.00
IUUC-Dno-029207	Dasypus novemcinctus	70.30	2.00e-38	152.00
IUUC-Dor-030912	Dipodomys ordii	42.66	5.00e-24	103.00
IUUC-Dme-031988	Drosophila melanogaster	28.16	3.00e-04	37.70
IUUC-Eca-034007	Equus caballus	80.00	2.00e-16	75.90
IUUC-Fca-036350	Felis catus	64.43	2.00e-49	188.00
IUUC-Fal-037192	Ficedula albicollis	60.25	3.00e-45	173.00
IUUC-Gmo-038921	Gadus morhua	49.08	1.00e-34	138.00
IUUC-Gga-041016	Gallus gallus	61.74	3.00e-44	170.00
IUUC-Gac-042560	Gasterosteus aculeatus	38.69	2.00e-26	111.00
IUUC-Ggo-045419	Gorilla gorilla	67.12	7.00e-53	199.00
IUUC-Hsa-046547	Homo sapiens	67.12	8.00e-53	199.00
IUUC-Itr-048225	Ictidomys tridecemlineatus	66.89	5.00e-53	199.00
IUUC-Lch-050463	Latimeria chalumnae	54.49	5.00e-42	163.00
IUUC-Loc-052053	Lepisosteus oculatus	51.61	1.00e-43	168.00
IUUC-Laf-053893	Loxodonta africana	59.76	1.00e-51	195.00
IUUC-Mcc-055347	Macaca mulatta	67.54	6.00e-42	163.00
IUUC-Mdo-062169	Monodelphis domestica	60.75	5.00e-29	118.00
IUUC-Mmu-064366	Mus musculus	66.91	7.00e-51	192.00
IUUC-Mpu-066593	Mustela putorius furo	60.61	5.00e-52	196.00
IUUC-Mlu-066926	Myotis lucifugus	67.59	6.00e-53	199.00
IUUC-Nle-069724	Nomascus leucogenys	66.90	3.00e-52	197.00
IUUC-Opr-070679	Ochotona princeps	69.23	7.00e-52	196.00
IUUC-Ont-071332	Oreochromis niloticus	44.67	1.00e-31	128.00
IUUC-Ola-086869	Oryzias latipes	45.09	2.00e-30	124.00
IUUC-Oga-089124	Otolemur garnettii	65.99	5.00e-51	193.00
IUUC-Oar-089799	Ovis aries	76.67	1.00e-38	150.00
IUUC-Ptr-091186	Pan troglodytes	76.92	2.00e-39	153.00
IUUC-Pan-092150	Papio anubis	66.43	3.00e-51	194.00
IUUC-Pma-094129	Petromyzon marinus	43.33	4.00e-17	80.50
IUUC-Pfo-096892	Poecilia formosa	45.16	1.00e-28	118.00
IUUC-Pab-097822	Pongo abelii	66.90	3.00e-52	197.00
IUUC-Pca-101058	Procavia capensis	65.03	2.00e-48	184.00
IUUC-Pva-102932	Pteropus vampyrus	66.23	3.00e-52	197.00
IUUC-Rno-105050	Rattus norvegicus	63.69	4.00e-53	200.00
IUUC-Sha-106738	Sarcophilus harrisii	78.89	1.00e-38	150.00
IUUC-Ssc-115973	Sus scrofa	64.90	7.00e-52	196.00
IUUC-Tgu-116663	Taeniopygia guttata	72.04	6.00e-34	134.00
IUUC-Tru-118654	Takifugu rubripes	45.86	2.00e-32	130.00
IUUC-Ttr-128418	Tursiops truncatus	65.81	4.00e-53	200.00
IUUC-Vpa-130268	Vicugna pacos	59.00	2.00e-28	117.00
IUUC-Xtr-132506	Xenopus tropicalis	57.05	2.00e-45	174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence