iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066679

Ensembl Protein ID

ENSMPUP00000005374.1

UniProt Accession

M3Y223; M3Y223_MUSPF

Genbank Protein ID

ENSMPUP00000005374

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01073924

Gene Name

TRIM33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005413.1	ENSMPUT00000005463.1	ENSMPUP00000005374.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-06	27.9	53	113
E3 activity/RING/PHD	2.90e-09	37.0	816	861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadCl...qkw........pglknssskefrCPlCr 46
           Ca+C++++    + +p++lpC H f++ Cl   ++          +   ++ + +rCP+Cr
   Q: 53   CAVCQQSLqsrrEAEPKLLPCLHSFCLRCLpepERQlsvsipggSNGDIQQVGVIRCPVCR 113
           ******999888556***************88744458788666444455666678****8 PP

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C+vC++gg+    l++CekC ++fH +C+ ++   ++p+ + wiC+ Cr+
   Q: 816  DWCAVCQNGGD----LLCCEKCPKVFHLTCHVPT-LLSFPSGD-WICTFCRD 861
           79*********....*******************.*******7.******85 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

XSAPAASAPA ASVGPGVPGG AVSTPAPAPA SAPAPGPSAG PPPGPPASLL DTCAVCQQSL 60
QSRREAEPKL LPCLHSFCLR CLPEPERQLS VSIPGGSNGD IQQVGVIRCP VCRQECRQID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNCTCGGCCC CGGCTGCCTC AGCCCCTGCG GCCTCAGTGG GCCCTGGAGT TCCCGGGGGC 60
GCGGTATCGA CGCCGGCCCC AGCTCCAGCC TCGGCTCCCG CTCCGGGTCC GTCGGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR019786--Zinc_finger_PHD-type_CS
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0030514--P:negative regulation of BMP signaling pathway
GO:0016567--P:protein ubiquitination
GO:0017015--P:regulation of transforming growth factor beta receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002364	Ailuropoda melanoleuca	98.51	0.00e+00	1746.00
IUUC-Apl-003894	Anas platyrhynchos	92.19	0.00e+00	1607.00
IUUC-Aca-004658	Anolis carolinensis	90.58	0.00e+00	1569.00
IUUC-Ath-006656	Arabidopsis thaliana	35.96	3.00e-12	68.20
IUUC-Ame-011619	Astyanax mexicanus	61.76	0.00e+00	1064.00
IUUC-Bta-013341	Bos taurus	97.02	0.00e+00	1696.00
IUUC-Cel-018225	Caenorhabditis elegans	19.67	6.00e-17	83.20
IUUC-Cja-018733	Callithrix jacchus	98.31	0.00e+00	1756.00
IUUC-Cfa-020725	Canis familiaris	99.40	0.00e+00	1720.00
IUUC-Cpo-021833	Cavia porcellus	97.91	0.00e+00	1734.00
IUUC-Csa-023040	Chlorocebus sabaeus	98.61	0.00e+00	1702.00
IUUC-Cho-024934	Choloepus hoffmanni	95.48	0.00e+00	1620.00
IUUC-Cin-025200	Ciona intestinalis	32.31	7.00e-46	179.00
IUUC-Csv-026278	Ciona savignyi	47.25	3.00e-20	92.00
IUUC-Dre-027797	Danio rerio	72.93	1.00e-171	597.00
IUUC-Dno-028955	Dasypus novemcinctus	98.11	0.00e+00	1799.00
IUUC-Dme-032143	Drosophila melanogaster	32.27	9.00e-46	179.00
IUUC-Ete-032728	Echinops telfairi	95.68	0.00e+00	921.00
IUUC-Eca-033573	Equus caballus	97.82	0.00e+00	1718.00
IUUC-Eeu-035138	Erinaceus europaeus	86.24	0.00e+00	827.00
IUUC-Fca-035776	Felis catus	99.26	0.00e+00	1636.00
IUUC-Fal-037583	Ficedula albicollis	91.33	0.00e+00	1632.00
IUUC-Gmo-039353	Gadus morhua	62.05	0.00e+00	667.00
IUUC-Gga-040874	Gallus gallus	92.86	0.00e+00	1713.00
IUUC-Gac-041689	Gasterosteus aculeatus	56.40	0.00e+00	1114.00
IUUC-Ggo-045151	Gorilla gorilla	97.83	0.00e+00	1321.00
IUUC-Hsa-046169	Homo sapiens	98.61	0.00e+00	1702.00
IUUC-Hvu-047073	Hordeum vulgare	49.06	2.00e-12	68.60
IUUC-Itr-048377	Ictidomys tridecemlineatus	97.73	0.00e+00	749.00
IUUC-Lch-050411	Latimeria chalumnae	82.77	0.00e+00	1381.00
IUUC-Loc-051992	Lepisosteus oculatus	72.76	0.00e+00	1296.00
IUUC-Laf-054552	Loxodonta africana	97.80	0.00e+00	1643.00
IUUC-Mcc-055744	Macaca mulatta	98.51	0.00e+00	1699.00
IUUC-Meu-056647	Macropus eugenii	98.87	0.00e+00	703.00
IUUC-Mga-059589	Meleagris gallopavo	92.49	0.00e+00	970.00
IUUC-Mmr-060727	Microcebus murinus	98.81	0.00e+00	1736.00
IUUC-Mdo-063029	Monodelphis domestica	95.93	0.00e+00	1738.00
IUUC-Mmu-064033	Mus musculus	96.33	0.00e+00	1751.00
IUUC-Mlu-067286	Myotis lucifugus	97.90	0.00e+00	1631.00
IUUC-Nle-069156	Nomascus leucogenys	98.31	0.00e+00	1695.00
IUUC-Opr-070309	Ochotona princeps	87.27	0.00e+00	1273.00
IUUC-Ont-071586	Oreochromis niloticus	54.58	0.00e+00	1055.00
IUUC-Oan-073205	Ornithorhynchus anatinus	95.42	0.00e+00	1454.00
IUUC-Ocu-074667	Oryctolagus cuniculus	95.21	0.00e+00	1607.00
IUUC-Ogl-077865	Oryza glaberrima	47.17	4.00e-12	67.40
IUUC-Olo-080499	Oryza longistaminata	47.17	4.00e-12	68.20
IUUC-Opu-083209	Oryza punctata	47.17	4.00e-12	67.80
IUUC-Ola-086481	Oryzias latipes	53.03	0.00e+00	1008.00
IUUC-Oga-089101	Otolemur garnettii	97.82	0.00e+00	1724.00
IUUC-Oar-090167	Ovis aries	97.91	0.00e+00	1740.00
IUUC-Ptr-090901	Pan troglodytes	98.71	0.00e+00	1704.00
IUUC-Pan-092448	Papio anubis	96.82	0.00e+00	1704.00
IUUC-Psi-093657	Pelodiscus sinensis	93.02	0.00e+00	1497.00
IUUC-Pma-094506	Petromyzon marinus	65.91	1.00e-50	191.00
IUUC-Pfo-097104	Poecilia formosa	69.15	5.00e-160	558.00
IUUC-Pab-097704	Pongo abelii	98.81	0.00e+00	1739.00
IUUC-Pca-101001	Procavia capensis	87.77	0.00e+00	648.00
IUUC-Pva-102733	Pteropus vampyrus	94.07	0.00e+00	1565.00
IUUC-Rno-105512	Rattus norvegicus	97.32	0.00e+00	1743.00
IUUC-Sha-107423	Sarcophilus harrisii	95.09	0.00e+00	1619.00
IUUC-Sar-113181	Sorex araneus	88.93	9.00e-145	507.00
IUUC-Ssc-116330	Sus scrofa	92.76	0.00e+00	1516.00
IUUC-Tgu-117388	Taeniopygia guttata	75.55	0.00e+00	1266.00
IUUC-Tru-118728	Takifugu rubripes	57.29	0.00e+00	999.00
IUUC-Tsy-119053	Tarsius syrichta	98.41	0.00e+00	1048.00
IUUC-Tni-120279	Tetraodon nigroviridis	47.12	3.00e-168	585.00
IUUC-Tae-124715	Triticum aestivum	47.17	6.00e-12	67.00
IUUC-Tbe-127573	Tupaia belangeri	89.15	0.00e+00	830.00
IUUC-Ttr-128594	Tursiops truncatus	98.01	0.00e+00	1736.00
IUUC-Vpa-130619	Vicugna pacos	92.05	0.00e+00	1093.00
IUUC-Xtr-132837	Xenopus tropicalis	85.52	0.00e+00	1505.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence