iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120410

UUCD1 version

UUC-TeN-00760

Ensembl Protein ID

ENSTNIP00000009147.1

UniProt Accession

H3CLL8; H3CLL8_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000006381.1	ENSTNIT00000009318.1	ENSTNIP00000009147.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-32	113.1	703	825

Active Site

Position(s)	Description	Evidence
795	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 206  lslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk..d 292
           +++F+++  e  + G  ++   ++   + y++ +++++  +q++we+l +f++e+r++fL+F+Tg+srlP+       p  +   k  +
   Q: 703  ITAFRWNTSERCLGGVCDFGTRNVGLLAHYED-LEPSNIRVQYLWEALTNFTNEDRSRFLRFITGRSRLPA-------PIYIFPDKqgS 783
           56677777777777777777777777778855.9************************************5.......44466666788 PP
   S: 293  asddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +++d +P+s+TC ++L LP+Y+s ++++ekL+yA  ++ +++
   Q: 784  ETTDAFPQSSTCSSTLYLPNYPSAKVCEEKLRYAAYNCVAID 825
           888*********************************998776 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

NPHLLLGRIR LLNRCIECLK RSESMPESLC YVPKEVCYKV CKDSSFSSSA SSGVPAGGSK 60
TLIPVFENPL QTPHIKKLCK YNIELKKGTC IRTTGEEYRN SQGLWVKITK EQMEEHRPGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCCCCATC TACTACTCGG CAGGATCCGT TTATTAAACA GATGTATAGA GTGTTTGAAA 60
AGGAGCGAGT CGATGCCGGA GTCCTTGTGT TATGTCCCCA AAGAGGTCTG CTACAAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	56.55	0.00e+00	961.00
IUUC-Apl-003715	Anas platyrhynchos	64.24	0.00e+00	958.00
IUUC-Aca-004377	Anolis carolinensis	60.75	0.00e+00	1026.00
IUUC-Ame-011918	Astyanax mexicanus	64.75	0.00e+00	1076.00
IUUC-Bta-012736	Bos taurus	57.13	0.00e+00	972.00
IUUC-Cja-019926	Callithrix jacchus	57.36	0.00e+00	972.00
IUUC-Cfa-020753	Canis familiaris	60.83	0.00e+00	716.00
IUUC-Cpo-021415	Cavia porcellus	57.13	0.00e+00	970.00
IUUC-Csa-023096	Chlorocebus sabaeus	57.13	0.00e+00	967.00
IUUC-Dre-028746	Danio rerio	71.53	0.00e+00	1167.00
IUUC-Dno-029293	Dasypus novemcinctus	60.45	0.00e+00	646.00
IUUC-Dor-031113	Dipodomys ordii	62.09	0.00e+00	762.00
IUUC-Ete-032601	Echinops telfairi	53.98	0.00e+00	822.00
IUUC-Eca-034198	Equus caballus	56.08	0.00e+00	950.00
IUUC-Eeu-034708	Erinaceus europaeus	57.27	6.00e-146	511.00
IUUC-Fca-035478	Felis catus	57.45	0.00e+00	962.00
IUUC-Fal-037366	Ficedula albicollis	59.51	0.00e+00	999.00
IUUC-Gmo-039020	Gadus morhua	71.23	0.00e+00	937.00
IUUC-Gga-040332	Gallus gallus	62.07	0.00e+00	1048.00
IUUC-Gac-042336	Gasterosteus aculeatus	74.79	0.00e+00	1259.00
IUUC-Ggo-045382	Gorilla gorilla	57.13	0.00e+00	968.00
IUUC-Hsa-046562	Homo sapiens	57.13	0.00e+00	968.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	56.89	0.00e+00	966.00
IUUC-Lch-049606	Latimeria chalumnae	69.35	2.00e-126	446.00
IUUC-Loc-052448	Lepisosteus oculatus	63.67	0.00e+00	1041.00
IUUC-Laf-054507	Loxodonta africana	56.83	0.00e+00	973.00
IUUC-Mcc-055690	Macaca mulatta	57.13	0.00e+00	968.00
IUUC-Meu-055970	Macropus eugenii	57.81	0.00e+00	954.00
IUUC-Mga-059654	Meleagris gallopavo	64.38	0.00e+00	944.00
IUUC-Mmr-061069	Microcebus murinus	57.01	0.00e+00	966.00
IUUC-Mdo-062547	Monodelphis domestica	58.63	6.00e-137	480.00
IUUC-Mmu-063096	Mus musculus	57.36	0.00e+00	972.00
IUUC-Mpu-065846	Mustela putorius furo	57.01	0.00e+00	972.00
IUUC-Mlu-067992	Myotis lucifugus	58.10	0.00e+00	935.00
IUUC-Nle-069565	Nomascus leucogenys	55.17	0.00e+00	874.00
IUUC-Opr-070853	Ochotona princeps	53.41	5.00e-178	617.00
IUUC-Ont-071628	Oreochromis niloticus	75.47	0.00e+00	1229.00
IUUC-Ocu-074094	Oryctolagus cuniculus	57.13	0.00e+00	969.00
IUUC-Ola-087384	Oryzias latipes	73.42	0.00e+00	1233.00
IUUC-Oga-088224	Otolemur garnettii	57.01	0.00e+00	970.00
IUUC-Oar-090043	Ovis aries	55.41	0.00e+00	911.00
IUUC-Ptr-090852	Pan troglodytes	56.89	0.00e+00	960.00
IUUC-Pan-092787	Papio anubis	57.13	0.00e+00	967.00
IUUC-Psi-092986	Pelodiscus sinensis	54.70	0.00e+00	702.00
IUUC-Pma-094416	Petromyzon marinus	32.82	2.00e-123	436.00
IUUC-Pfo-096720	Poecilia formosa	74.85	0.00e+00	1256.00
IUUC-Pab-098325	Pongo abelii	62.62	0.00e+00	786.00
IUUC-Pca-100885	Procavia capensis	54.76	0.00e+00	759.00
IUUC-Pva-102829	Pteropus vampyrus	54.22	0.00e+00	647.00
IUUC-Rno-104882	Rattus norvegicus	57.01	0.00e+00	969.00
IUUC-Sha-106811	Sarcophilus harrisii	75.00	1.00e-97	349.00
IUUC-Sar-113020	Sorex araneus	79.55	7.00e-84	305.00
IUUC-Ssc-115436	Sus scrofa	65.07	2.00e-104	372.00
IUUC-Tgu-117042	Taeniopygia guttata	61.48	0.00e+00	1045.00
IUUC-Tru-118419	Takifugu rubripes	81.85	0.00e+00	1309.00
IUUC-Tsy-118829	Tarsius syrichta	67.91	0.00e+00	704.00
IUUC-Tbe-128113	Tupaia belangeri	55.09	2.00e-115	410.00
IUUC-Ttr-128167	Tursiops truncatus	53.58	0.00e+00	884.00
IUUC-Xtr-132910	Xenopus tropicalis	52.21	0.00e+00	817.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence