iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049568

Ensembl Protein ID

ENSLACP00000014811.1

UniProt Accession

H3AYU0; H3AYU0_LATCH

Genbank Protein ID

ENSLACP00000014811

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AFYH01139789

Gene Name

LCK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000013039.1	ENSLACT00000014915.1	ENSLACP00000014811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.40e-16	58.1	66	123

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++v +ly+ye+++d++L +++G++++++   e++++W+++ + ++g +G++P nFv+k +
   Q: 66   DNLVVALYNYEPAHDGDLGFQEGEKLQIL---EESGEWWRALSLTTGNEGFIPYNFVAKFN 123
           5789*************************...99***********************9875 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGCNCSSDYD DEWIENIDEI CEHCNCPYPP ESKPQVGVRQ NGTRAEVFDP LVPYERQTPP 60
CSPLPDNLVV ALYNYEPAHD GDLGFQEGEK LQILEESGEW WRALSLTTGN EGFIPYNFVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGTA ACTGCAGTTC AGACTATGAT GATGAGTGGA TTGAGAATAT TGATGAAATC 60
TGCGAGCATT GTAACTGCCC CTATCCACCA GAAAGCAAAC CACAGGTAGG TGGGATTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	73.48	0.00e+00	832.00
IUUC-Apl-004134	Anas platyrhynchos	78.03	0.00e+00	712.00
IUUC-Bta-013264	Bos taurus	77.73	0.00e+00	851.00
IUUC-Cfa-021161	Canis familiaris	72.51	0.00e+00	826.00
IUUC-Cpo-022492	Cavia porcellus	77.34	0.00e+00	851.00
IUUC-Dre-028005	Danio rerio	70.18	0.00e+00	728.00
IUUC-Dno-029365	Dasypus novemcinctus	74.46	0.00e+00	804.00
IUUC-Dor-030892	Dipodomys ordii	76.81	0.00e+00	809.00
IUUC-Eca-033325	Equus caballus	75.83	0.00e+00	817.00
IUUC-Eeu-035004	Erinaceus europaeus	70.27	0.00e+00	650.00
IUUC-Fca-035908	Felis catus	77.34	0.00e+00	846.00
IUUC-Gmo-038984	Gadus morhua	67.50	0.00e+00	726.00
IUUC-Gga-040997	Gallus gallus	81.45	0.00e+00	889.00
IUUC-Gac-041854	Gasterosteus aculeatus	72.37	0.00e+00	773.00
IUUC-Gma-043628	Glycine max	30.27	3.00e-21	97.10
IUUC-Ggo-045238	Gorilla gorilla	73.06	0.00e+00	832.00
IUUC-Hsa-047039	Homo sapiens	77.34	0.00e+00	846.00
IUUC-Itr-048479	Ictidomys tridecemlineatus	77.73	0.00e+00	851.00
IUUC-Loc-052222	Lepisosteus oculatus	69.05	0.00e+00	719.00
IUUC-Laf-054499	Loxodonta africana	73.11	0.00e+00	831.00
IUUC-Meu-056879	Macropus eugenii	75.19	0.00e+00	825.00
IUUC-Mga-059971	Meleagris gallopavo	79.88	0.00e+00	865.00
IUUC-Mmr-060740	Microcebus murinus	77.34	0.00e+00	846.00
IUUC-Mdo-062192	Monodelphis domestica	77.54	0.00e+00	847.00
IUUC-Mmu-064241	Mus musculus	77.58	0.00e+00	847.00
IUUC-Mpu-066595	Mustela putorius furo	77.00	0.00e+00	840.00
IUUC-Mlu-067069	Myotis lucifugus	76.17	0.00e+00	839.00
IUUC-Opr-070472	Ochotona princeps	73.00	0.00e+00	826.00
IUUC-Ont-071711	Oreochromis niloticus	72.96	0.00e+00	756.00
IUUC-Ocu-074221	Oryctolagus cuniculus	76.65	0.00e+00	832.00
IUUC-Ola-087000	Oryzias latipes	70.45	0.00e+00	750.00
IUUC-Oga-088225	Otolemur garnettii	77.34	0.00e+00	843.00
IUUC-Oar-090244	Ovis aries	68.86	0.00e+00	794.00
IUUC-Pan-091804	Papio anubis	77.54	0.00e+00	850.00
IUUC-Psi-093252	Pelodiscus sinensis	73.69	0.00e+00	779.00
IUUC-Pma-094311	Petromyzon marinus	71.27	0.00e+00	674.00
IUUC-Pfo-096542	Poecilia formosa	71.35	0.00e+00	775.00
IUUC-Pab-098168	Pongo abelii	78.57	0.00e+00	815.00
IUUC-Rno-105542	Rattus norvegicus	77.19	0.00e+00	847.00
IUUC-Sha-107524	Sarcophilus harrisii	76.56	0.00e+00	843.00
IUUC-Sar-113235	Sorex araneus	71.79	0.00e+00	703.00
IUUC-Ssc-115624	Sus scrofa	77.34	0.00e+00	847.00
IUUC-Tru-118559	Takifugu rubripes	70.13	0.00e+00	750.00
IUUC-Tni-119928	Tetraodon nigroviridis	64.33	0.00e+00	661.00
IUUC-Ttr-129002	Tursiops truncatus	70.35	0.00e+00	785.00
IUUC-Xtr-132224	Xenopus tropicalis	75.78	0.00e+00	826.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence