iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088402

Ensembl Protein ID

ENSOGAP00000011754.2

UniProt Accession

H0X8E4; H0X8E4_OTOGA

Genbank Protein ID

ENSOGAP00000011754

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03020734

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013119.2	ENSOGAT00000013122.2	ENSOGAP00000011754.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.60	0.00e+00	693.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MESGGRPSLG QFILLGTSSV VTAFLYSVYR QKAQVAQELK GAKKIHLGDD LKSILSEAPG 60
KCVPYAVIEG AVRSVKETLN SQFVENCKGV IQRLTLQEHK IVWNRTTHLW NDCSKIIHQR 120

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Nucleotide Sequence
(Fasta)

ATGGAGAGCG GAGGACGGCC ATCTCTGGGC CAATTCATCC TCCTGGGCAC CAGCTCCGTC 60
GTCACCGCCT TCCTGTACTC CGTGTACCGG CAAAAGGCCC AGGTTGCCCA AGAGCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002287	Ailuropoda melanoleuca	92.33	0.00e+00	648.00
IUUC-Atr-002698	Amborella trichopoda	24.58	1.00e-10	60.50
IUUC-Aca-005039	Anolis carolinensis	38.26	2.00e-64	239.00
IUUC-Aly-006181	Arabidopsis lyrata	28.08	2.00e-21	96.30
IUUC-Ath-007438	Arabidopsis thaliana	28.37	3.00e-22	99.40
IUUC-Ame-010671	Astyanax mexicanus	62.50	1.00e-132	465.00
IUUC-Bta-012407	Bos taurus	81.02	1.00e-167	582.00
IUUC-Bdi-014735	Brachypodium distachyon	24.56	4.00e-16	78.60
IUUC-Bol-015493	Brassica oleracea	26.65	2.00e-23	102.00
IUUC-Bra-016933	Brassica rapa	26.81	1.00e-20	94.00
IUUC-Cja-019709	Callithrix jacchus	94.08	0.00e+00	635.00
IUUC-Cfa-020818	Canis familiaris	92.90	0.00e+00	658.00
IUUC-Cpo-022490	Cavia porcellus	92.33	0.00e+00	631.00
IUUC-Csa-023259	Chlorocebus sabaeus	94.60	0.00e+00	693.00
IUUC-Cho-024730	Choloepus hoffmanni	92.90	0.00e+00	679.00
IUUC-Cin-025301	Ciona intestinalis	31.23	6.00e-46	177.00
IUUC-Dre-028644	Danio rerio	63.07	3.00e-135	474.00
IUUC-Dno-028925	Dasypus novemcinctus	90.06	0.00e+00	669.00
IUUC-Dor-030692	Dipodomys ordii	93.47	0.00e+00	653.00
IUUC-Dme-031761	Drosophila melanogaster	30.06	3.00e-33	135.00
IUUC-Ete-032329	Echinops telfairi	82.39	8.00e-156	542.00
IUUC-Eca-034008	Equus caballus	89.49	0.00e+00	664.00
IUUC-Eeu-034895	Erinaceus europaeus	74.04	1.00e-120	425.00
IUUC-Fca-036104	Felis catus	92.05	0.00e+00	655.00
IUUC-Fal-036900	Ficedula albicollis	72.30	1.00e-138	485.00
IUUC-Gmo-039049	Gadus morhua	59.38	5.00e-109	387.00
IUUC-Gga-040254	Gallus gallus	71.02	7.00e-146	509.00
IUUC-Gac-042277	Gasterosteus aculeatus	60.23	4.00e-135	473.00
IUUC-Gma-043979	Glycine max	26.51	6.00e-18	84.70
IUUC-Ggo-045509	Gorilla gorilla	94.60	0.00e+00	693.00
IUUC-Hsa-046597	Homo sapiens	94.60	0.00e+00	693.00
IUUC-Hvu-047335	Hordeum vulgare	24.54	2.00e-17	82.80
IUUC-Itr-048691	Ictidomys tridecemlineatus	94.60	0.00e+00	660.00
IUUC-Lch-050344	Latimeria chalumnae	67.90	6.00e-146	509.00
IUUC-Loc-052376	Lepisosteus oculatus	67.61	5.00e-151	526.00
IUUC-Laf-054414	Loxodonta africana	92.33	0.00e+00	677.00
IUUC-Mcc-054604	Macaca mulatta	94.32	0.00e+00	692.00
IUUC-Meu-056087	Macropus eugenii	84.66	6.00e-172	596.00
IUUC-Mtr-057779	Medicago truncatula	26.74	9.00e-18	84.00
IUUC-Mga-060188	Meleagris gallopavo	73.40	6.00e-145	506.00
IUUC-Mmr-060704	Microcebus murinus	94.89	0.00e+00	691.00
IUUC-Mdo-062842	Monodelphis domestica	84.66	9.00e-166	575.00
IUUC-Mmu-064324	Mus musculus	90.34	1.00e-179	622.00
IUUC-Mpu-065940	Mustela putorius furo	90.06	3.00e-180	623.00
IUUC-Mlu-067028	Myotis lucifugus	92.61	0.00e+00	682.00
IUUC-Nle-069254	Nomascus leucogenys	87.57	0.00e+00	639.00
IUUC-Opr-070827	Ochotona princeps	87.22	0.00e+00	648.00
IUUC-Ont-072008	Oreochromis niloticus	63.07	4.00e-141	493.00
IUUC-Oan-072935	Ornithorhynchus anatinus	78.69	2.00e-166	578.00
IUUC-Ocu-074526	Oryctolagus cuniculus	92.05	0.00e+00	636.00
IUUC-Obr-076592	Oryza brachyantha	26.67	9.00e-21	94.00
IUUC-Ogl-077732	Oryza glaberrima	26.67	2.00e-20	93.20
IUUC-Oin-080188	Oryza indica	26.67	2.00e-20	93.20
IUUC-Olo-080705	Oryza longistaminata	25.00	8.00e-13	68.60
IUUC-Ola-087288	Oryzias latipes	57.95	2.00e-126	444.00
IUUC-Oar-089851	Ovis aries	94.44	7.00e-91	325.00
IUUC-Ptr-091226	Pan troglodytes	94.32	0.00e+00	692.00
IUUC-Pan-092575	Papio anubis	94.03	0.00e+00	691.00
IUUC-Psi-094062	Pelodiscus sinensis	76.70	1.00e-164	572.00
IUUC-Pma-094501	Petromyzon marinus	37.57	2.00e-46	179.00
IUUC-Ppa-095285	Physcomitrella patens	25.23	2.00e-15	76.60
IUUC-Pfo-096146	Poecilia formosa	57.39	2.00e-122	431.00
IUUC-Pab-098524	Pongo abelii	94.32	0.00e+00	692.00
IUUC-Pop-099864	Populus trichocarpa	26.42	6.00e-18	84.70
IUUC-Pca-100314	Procavia capensis	91.48	0.00e+00	670.00
IUUC-Ppe-101663	Prunus persica	25.45	3.00e-16	79.30
IUUC-Pva-102947	Pteropus vampyrus	92.05	0.00e+00	676.00
IUUC-Rno-105024	Rattus norvegicus	90.62	0.00e+00	635.00
IUUC-Sha-107500	Sarcophilus harrisii	69.14	1.00e-123	435.00
IUUC-Smo-109194	Selaginella moellendorffii	26.36	4.00e-19	88.60
IUUC-Sit-109922	Setaria italica	25.66	2.00e-19	89.40
IUUC-Sly-111826	Solanum lycopersicum	27.60	5.00e-20	92.00
IUUC-Stu-112907	Solanum tuberosum	27.51	5.00e-19	88.60
IUUC-Sar-113522	Sorex araneus	89.42	1.00e-165	575.00
IUUC-Sbi-114536	Sorghum bicolor	25.95	3.00e-21	95.90
IUUC-Ssc-115445	Sus scrofa	93.47	0.00e+00	640.00
IUUC-Tgu-116551	Taeniopygia guttata	71.59	8.00e-135	473.00
IUUC-Tru-118407	Takifugu rubripes	57.39	4.00e-117	414.00
IUUC-Tsy-118794	Tarsius syrichta	91.19	0.00e+00	666.00
IUUC-Tni-120128	Tetraodon nigroviridis	64.83	2.00e-94	338.00
IUUC-Tca-121508	Theobroma cacao	26.38	2.00e-20	92.80
IUUC-Tae-125185	Triticum aestivum	25.00	5.00e-20	91.70
IUUC-Tur-126470	Triticum urartu	24.71	6.00e-20	91.30
IUUC-Tbe-127432	Tupaia belangeri	93.47	0.00e+00	635.00
IUUC-Ttr-128573	Tursiops truncatus	89.49	0.00e+00	643.00
IUUC-Vpa-130583	Vicugna pacos	91.35	1.00e-173	601.00
IUUC-Vvi-131710	Vitis vinifera	25.27	1.00e-16	80.50
IUUC-Xtr-132009	Xenopus tropicalis	61.30	3.00e-135	474.00
IUUC-Xma-134121	Xiphophorus maculatus	58.07	4.00e-127	447.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence