iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-089088

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03044757

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015682.2	ENSOGAT00000015688.2	ENSOGAP00000014052.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	91.48	0.00e+00	1907.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.96	7.00e-42	167.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

VRLFKRKHLT AVDCQHLAPS HLSVAQPFGR RWTSRDPNHG LYPKPRTRRG SRAQGWQRQN 60
PELFLAGQQL CTNDMAKSSS VGQDGCQDSE GNMIFAAESS CALPQEHDGE ARSGTSRPPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGACTGT TTAAGCGGAA GCATCTTACA GCCGTCGACT GCCAGCATCT GGCTCCGAGT 60
CATTTGTCTG TGGCCCAGCC TTTTGGTCGA AGATGGACAA GCAGAGACCC GAACCATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	29.57	3.00e-04	41.20
IUUC-Aml-001396	Ailuropoda melanoleuca	88.42	0.00e+00	1892.00
IUUC-Atr-002826	Amborella trichopoda	40.00	1.00e-03	39.70
IUUC-Apl-003317	Anas platyrhynchos	53.56	0.00e+00	932.00
IUUC-Aca-004498	Anolis carolinensis	54.29	0.00e+00	956.00
IUUC-Aly-006174	Arabidopsis lyrata	35.00	2.00e-05	41.20
IUUC-Ath-007293	Arabidopsis thaliana	23.41	4.00e-03	37.40
IUUC-Ani-009226	Aspergillus nidulans	30.83	1.00e-05	45.40
IUUC-Ate-010526	Aspergillus terreus	38.24	1.00e-03	38.90
IUUC-Ame-011808	Astyanax mexicanus	59.59	6.00e-135	473.00
IUUC-Bta-013250	Bos taurus	86.81	0.00e+00	1848.00
IUUC-Bol-015348	Brassica oleracea	38.81	5.00e-03	37.40
IUUC-Cja-019638	Callithrix jacchus	90.81	0.00e+00	1971.00
IUUC-Cfa-020195	Canis familiaris	90.33	0.00e+00	1816.00
IUUC-Cpo-022269	Cavia porcellus	84.31	0.00e+00	1770.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	4.00e-08	54.30
IUUC-Csa-024060	Chlorocebus sabaeus	92.38	0.00e+00	1785.00
IUUC-Cho-025003	Choloepus hoffmanni	87.88	0.00e+00	712.00
IUUC-Cin-025694	Ciona intestinalis	27.17	2.00e-30	127.00
IUUC-Dre-028083	Danio rerio	50.34	0.00e+00	858.00
IUUC-Dno-029203	Dasypus novemcinctus	84.34	0.00e+00	1748.00
IUUC-Dor-030477	Dipodomys ordii	95.40	0.00e+00	778.00
IUUC-Ete-032861	Echinops telfairi	86.32	0.00e+00	1831.00
IUUC-Eca-033205	Equus caballus	89.20	0.00e+00	1940.00
IUUC-Eeu-034784	Erinaceus europaeus	85.78	0.00e+00	1212.00
IUUC-Fca-035797	Felis catus	87.79	0.00e+00	1897.00
IUUC-Gmo-038855	Gadus morhua	46.27	6.00e-124	438.00
IUUC-Gga-040326	Gallus gallus	50.72	0.00e+00	986.00
IUUC-Gac-042240	Gasterosteus aculeatus	46.14	0.00e+00	731.00
IUUC-Ggo-045050	Gorilla gorilla	87.93	0.00e+00	1835.00
IUUC-Hsa-046650	Homo sapiens	91.48	0.00e+00	1933.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	95.09	0.00e+00	768.00
IUUC-Lch-050231	Latimeria chalumnae	43.42	1.00e-167	583.00
IUUC-Loc-051884	Lepisosteus oculatus	49.15	0.00e+00	976.00
IUUC-Lma-053267	Leptosphaeria maculans	22.42	3.00e-03	37.70
IUUC-Laf-053843	Loxodonta africana	87.95	0.00e+00	1884.00
IUUC-Mcc-055570	Macaca mulatta	91.58	0.00e+00	1961.00
IUUC-Meu-056798	Macropus eugenii	66.92	2.00e-152	533.00
IUUC-Mtr-057915	Medicago truncatula	38.24	5.00e-05	43.90
IUUC-Mga-059648	Meleagris gallopavo	51.51	0.00e+00	947.00
IUUC-Mmr-060757	Microcebus murinus	89.85	0.00e+00	1862.00
IUUC-Mdo-061913	Monodelphis domestica	67.83	0.00e+00	1366.00
IUUC-Mmu-064337	Mus musculus	86.60	0.00e+00	1873.00
IUUC-Mpu-066483	Mustela putorius furo	87.27	0.00e+00	1898.00
IUUC-Mlu-068204	Myotis lucifugus	82.73	0.00e+00	1778.00
IUUC-Ncr-068735	Neurospora crassa	35.94	7.00e-03	36.60
IUUC-Nle-070053	Nomascus leucogenys	91.20	0.00e+00	1900.00
IUUC-Opr-070588	Ochotona princeps	82.70	0.00e+00	1749.00
IUUC-Ont-072655	Oreochromis niloticus	46.64	0.00e+00	761.00
IUUC-Oan-073351	Ornithorhynchus anatinus	61.22	0.00e+00	1286.00
IUUC-Ocu-074465	Oryctolagus cuniculus	87.98	0.00e+00	1802.00
IUUC-Oin-079176	Oryza indica	23.31	1.00e-05	44.30
IUUC-Olu-087831	Ostreococcus lucimarinus	31.34	3.00e-66	248.00
IUUC-Oar-089870	Ovis aries	85.85	0.00e+00	1805.00
IUUC-Ptr-090957	Pan troglodytes	91.30	0.00e+00	1900.00
IUUC-Pan-092632	Papio anubis	91.29	0.00e+00	1905.00
IUUC-Psi-093035	Pelodiscus sinensis	55.01	0.00e+00	1130.00
IUUC-Pno-094870	Phaeosphaeria nodorum	30.95	2.00e-03	38.10
IUUC-Ppa-095660	Physcomitrella patens	39.73	7.00e-04	40.00
IUUC-Pfo-096902	Poecilia formosa	45.02	0.00e+00	696.00
IUUC-Pab-098206	Pongo abelii	91.10	0.00e+00	1791.00
IUUC-Pop-098801	Populus trichocarpa	37.68	1.00e-04	42.40
IUUC-Pca-100238	Procavia capensis	82.22	0.00e+00	1747.00
IUUC-Ppe-101748	Prunus persica	33.82	6.00e-03	37.00
IUUC-Pva-103182	Pteropus vampyrus	86.33	0.00e+00	1819.00
IUUC-Pte-104033	Pyrenophora teres	33.90	2.50e-02	34.70
IUUC-Pyt-104599	Pyrenophora triticirepentis	25.00	1.20e-02	35.40
IUUC-Rno-105141	Rattus norvegicus	86.90	0.00e+00	1871.00
IUUC-Sce-106341	Saccharomyces cerevisiae	27.66	1.00e-03	38.50
IUUC-Sha-106827	Sarcophilus harrisii	65.97	0.00e+00	1425.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.49	4.00e-42	166.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.96	2.00e-42	167.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	24.72	8.00e-05	42.70
IUUC-Sly-111170	Solanum lycopersicum	37.88	8.00e-03	35.40
IUUC-Sre-115025	Sporisorium reilianum	33.23	2.00e-38	154.00
IUUC-Ssc-116188	Sus scrofa	92.91	0.00e+00	1260.00
IUUC-Tgu-116612	Taeniopygia guttata	57.38	7.00e-163	566.00
IUUC-Tsy-119560	Tarsius syrichta	81.85	9.00e-115	408.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.57	0.00e+00	712.00
IUUC-Tca-121338	Theobroma cacao	32.71	3.00e-03	37.70
IUUC-Tre-122089	Trichoderma reesei	38.89	5.00e-04	40.00
IUUC-Tme-127009	Tuber melanosporum	30.49	3.00e-03	38.10
IUUC-Tbe-127431	Tupaia belangeri	87.79	0.00e+00	1611.00
IUUC-Ttr-128744	Tursiops truncatus	85.45	0.00e+00	1808.00
IUUC-Uma-129536	Ustilago maydis	33.24	9.00e-40	159.00
IUUC-Vpa-130123	Vicugna pacos	69.96	1.00e-91	330.00
IUUC-Vvi-131025	Vitis vinifera	36.76	8.00e-04	39.70
IUUC-Xtr-132902	Xenopus tropicalis	58.18	0.00e+00	1014.00
IUUC-Xma-133978	Xiphophorus maculatus	46.00	9.00e-155	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence