iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tbe-127426

UUCD1 version

UUC-TuB-00188

Ensembl Protein ID

ENSTBEP00000005160.1

UniProt Accession

A0A077B6X9; A0A077B6X9_TUPBE

Genbank Protein ID

AIL01924.1

Protein Name

TRIM5-1 alpha isoform

Genbank Nucleotide ID

KJ697757

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTBEG00000005986.1	ENSTBET00000005996.1	ENSTBEP00000005160.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-07	30.5	15	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle + + p +l+CgH f+++Cl ++   +   + +e  CP Cr
   Q: 15   CPICLELLTE-PQSLDCGHSFCQSCLiENQTKSTVGQEGENCCPMCR 60
           ********99.**************9944447888999********8 PP

Organism

Tupaia belangeri

Protein Sequence
(Fasta)

MALAILVDVK EEVTCPICLE LLTEPQSLDC GHSFCQSCLI ENQTKSTVGQ EGENCCPMCR 60
VSYQPGNLRT NRHLANIAER LRKANVSLEE GQRVHHCARH GEKLLLFCKE DGKAICLLCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTTGG CAATCCTGGT GGATGTAAAG GAGGAGGTGA CCTGCCCCAT CTGCCTGGAG 60
CTCCTAACAG AACCCCAGAG CCTAGACTGT GGACACAGCT TCTGCCAGTC CTGCCTCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0479--Metal-binding
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR010908--Longin_dom
IPR003877--SPRY_dom
IPR032917--TRIM5
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008013	Aspergillus clavatus	56.76	2.00e-05	44.70
IUUC-Cja-019944	Callithrix jacchus	54.10	2.00e-133	468.00
IUUC-Csa-023609	Chlorocebus sabaeus	51.45	2.00e-140	491.00
IUUC-Dor-030700	Dipodomys ordii	48.05	1.00e-128	452.00
IUUC-Ete-033021	Echinops telfairi	47.77	8.00e-103	367.00
IUUC-Eeu-034968	Erinaceus europaeus	48.62	4.00e-105	374.00
IUUC-Ggo-044783	Gorilla gorilla	53.52	2.00e-137	481.00
IUUC-Hsa-046573	Homo sapiens	53.61	3.00e-141	494.00
IUUC-Mcc-055525	Macaca mulatta	53.09	1.00e-141	496.00
IUUC-Mmr-061336	Microcebus murinus	51.10	1.00e-123	436.00
IUUC-Nle-069081	Nomascus leucogenys	53.21	2.00e-138	484.00
IUUC-Opr-071057	Ochotona princeps	49.90	3.00e-113	401.00
IUUC-Ocu-073956	Oryctolagus cuniculus	53.28	7.00e-129	454.00
IUUC-Ptr-090927	Pan troglodytes	52.81	4.00e-137	480.00
IUUC-Pan-092730	Papio anubis	54.09	2.00e-144	505.00
IUUC-Pab-098782	Pongo abelii	54.02	9.00e-143	499.00
IUUC-Sar-113094	Sorex araneus	46.93	5.00e-98	350.00
IUUC-Ssc-115715	Sus scrofa	53.14	1.00e-136	479.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence