iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009290.1	ENSSHAT00000010870.1	ENSSHAP00000010776.1
ENSSHAG00000009290.1	ENSSHAT00000010871.1	ENSSHAP00000010777.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	42.47	1.00e-08	58.20	IUUC-Ath-007116
E3 activity/RING/RING	74.78	0.00e+00	681.00	IUUC-Hsa-046155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MEDVQLIAPN MTSTEKEKPI SGVSRQISVS EFSCHCCYDI LVNPTTLNCG HSLCRHCLAL 60
WWVSSKKTEC PECREKWEGF PKVNILLRQS RTENLDSIHF FITDFTWSHY INNCQTSCSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTAATGCA GCTCTTAAGA CTGAAATAGA TATATCTTCA GAGTACGGAA TGATCTAGAA 60
AAAGATGGAA GACGTTCAGC TAATTGCACC CAACATGACG AGCACTGAAA AAGAGAAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001660--SAM
IPR013761--SAM/pointed
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50105--SAM_DOMAIN
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00536--SAM_1
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00454--SAM

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:1903895--P:negative regulation of IRE1-mediated unfolded protein response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001856	Ailuropoda melanoleuca	74.34	0.00e+00	641.00
IUUC-Apl-004001	Anas platyrhynchos	73.17	0.00e+00	629.00
IUUC-Aca-005095	Anolis carolinensis	69.02	1.00e-174	605.00
IUUC-Aly-005558	Arabidopsis lyrata	41.03	2.00e-09	56.60
IUUC-Ath-007116	Arabidopsis thaliana	42.47	7.00e-10	58.20
IUUC-Ame-010623	Astyanax mexicanus	55.76	2.00e-136	478.00
IUUC-Bta-012806	Bos taurus	73.67	0.00e+00	628.00
IUUC-Bol-015948	Brassica oleracea	39.73	6.00e-09	55.10
IUUC-Bra-017661	Brassica rapa	36.36	3.00e-09	55.80
IUUC-Cel-018107	Caenorhabditis elegans	34.85	4.00e-06	45.40
IUUC-Cja-019478	Callithrix jacchus	74.56	0.00e+00	643.00
IUUC-Cfa-021253	Canis familiaris	73.89	0.00e+00	633.00
IUUC-Cpo-022551	Cavia porcellus	74.56	0.00e+00	635.00
IUUC-Csa-023499	Chlorocebus sabaeus	74.56	0.00e+00	639.00
IUUC-Cho-024665	Choloepus hoffmanni	68.01	1.00e-108	385.00
IUUC-Dno-029161	Dasypus novemcinctus	75.00	0.00e+00	637.00
IUUC-Dor-030580	Dipodomys ordii	86.46	4.00e-143	500.00
IUUC-Ete-032643	Echinops telfairi	69.68	1.00e-168	585.00
IUUC-Eca-034435	Equus caballus	73.67	0.00e+00	628.00
IUUC-Eeu-034787	Erinaceus europaeus	50.67	7.00e-39	154.00
IUUC-Fca-035970	Felis catus	75.62	0.00e+00	639.00
IUUC-Fal-036727	Ficedula albicollis	71.11	0.00e+00	637.00
IUUC-Gmo-039048	Gadus morhua	58.77	3.00e-143	501.00
IUUC-Gga-041098	Gallus gallus	83.41	1.00e-114	405.00
IUUC-Gac-042246	Gasterosteus aculeatus	58.10	4.00e-138	484.00
IUUC-Ggo-045045	Gorilla gorilla	75.00	0.00e+00	642.00
IUUC-Hsa-046155	Homo sapiens	74.78	0.00e+00	642.00
IUUC-Itr-049066	Ictidomys tridecemlineatus	75.97	0.00e+00	632.00
IUUC-Lch-050654	Latimeria chalumnae	68.03	8.00e-169	586.00
IUUC-Loc-051851	Lepisosteus oculatus	62.91	4.00e-160	557.00
IUUC-Laf-053600	Loxodonta africana	74.78	0.00e+00	637.00
IUUC-Mcc-054824	Macaca mulatta	74.78	0.00e+00	640.00
IUUC-Meu-056707	Macropus eugenii	99.10	8.00e-129	452.00
IUUC-Mga-059577	Meleagris gallopavo	71.56	0.00e+00	632.00
IUUC-Mmr-061031	Microcebus murinus	75.00	0.00e+00	640.00
IUUC-Mdo-062696	Monodelphis domestica	83.74	0.00e+00	733.00
IUUC-Mmu-063190	Mus musculus	72.12	0.00e+00	665.00
IUUC-Mpu-065811	Mustela putorius furo	73.67	0.00e+00	626.00
IUUC-Mlu-067273	Myotis lucifugus	72.35	0.00e+00	634.00
IUUC-Nle-069226	Nomascus leucogenys	75.22	0.00e+00	642.00
IUUC-Opr-071014	Ochotona princeps	74.34	0.00e+00	657.00
IUUC-Ont-072113	Oreochromis niloticus	58.70	2.00e-144	504.00
IUUC-Oan-072720	Ornithorhynchus anatinus	67.51	1.00e-131	462.00
IUUC-Ocu-073920	Oryctolagus cuniculus	72.73	5.00e-179	620.00
IUUC-Ola-087064	Oryzias latipes	58.60	5.00e-142	497.00
IUUC-Oga-088121	Otolemur garnettii	75.22	0.00e+00	641.00
IUUC-Oar-090404	Ovis aries	73.89	0.00e+00	630.00
IUUC-Ptr-090824	Pan troglodytes	74.78	0.00e+00	641.00
IUUC-Pan-091820	Papio anubis	74.78	0.00e+00	640.00
IUUC-Psi-093328	Pelodiscus sinensis	73.89	0.00e+00	640.00
IUUC-Pma-094362	Petromyzon marinus	49.30	8.00e-116	410.00
IUUC-Pfo-096138	Poecilia formosa	58.64	4.00e-146	511.00
IUUC-Pab-097808	Pongo abelii	74.78	0.00e+00	638.00
IUUC-Pca-100409	Procavia capensis	71.46	1.00e-170	592.00
IUUC-Pva-103043	Pteropus vampyrus	73.86	5.00e-180	623.00
IUUC-Rno-105559	Rattus norvegicus	71.90	0.00e+00	670.00
IUUC-Ssc-115421	Sus scrofa	66.77	2.00e-108	385.00
IUUC-Tgu-116564	Taeniopygia guttata	71.52	0.00e+00	633.00
IUUC-Tru-118271	Takifugu rubripes	57.18	2.00e-126	445.00
IUUC-Tsy-119122	Tarsius syrichta	87.77	5.00e-96	344.00
IUUC-Tni-120019	Tetraodon nigroviridis	56.09	5.00e-121	427.00
IUUC-Tbe-127449	Tupaia belangeri	75.66	0.00e+00	645.00
IUUC-Ttr-128570	Tursiops truncatus	84.72	3.00e-135	474.00
IUUC-Vpa-130501	Vicugna pacos	76.05	3.00e-167	580.00
IUUC-Xtr-132154	Xenopus tropicalis	68.87	4.00e-176	610.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence