iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000002462.1	ENSONIT00000003080.1	ENSONIP00000003079.1
ENSONIG00000002462.1	ENSONIT00000003081.1	ENSONIP00000003080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.20e-08	32.9	341	379
UBD/Alpha-Helix/CUE	3.90e-10	39.9	461	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC++ + +  + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 341  CAICWDAMLT-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 379
           ******9988.999***************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 4    taleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
            +++q++e+FP++++ ++ ++L ++t s+e +++n+Leg 
   Q: 461  AMAHQIQEMFPQVPSYLVLQDL-QLTRSVEVTTDNILEGR 499
           69********************.***************95 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPLLFLERFP WPSLQTYTAL SVALLAGSIF SAYTTVTDPG FGALETDEAQ PPSEVERELL 60
KNDISNTELA TTVLWYLVTD SLFVWVLVNT FCCSLMLIAK MIQYVVFGPL RVSEKQHLKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTCCACA ATATAATCAA AAAATTAAAT CAACACATAT AAAAACATTT TCTTTTGTAA 60
TCACGGGGCA ACGAGTTATT AGTTAAATTA AACTGCTGAA TGAAAATATT TATTTTGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	72.35	0.00e+00	755.00
IUUC-Apl-003404	Anas platyrhynchos	74.21	0.00e+00	766.00
IUUC-Aca-004559	Anolis carolinensis	76.73	0.00e+00	726.00
IUUC-Ame-011640	Astyanax mexicanus	71.07	0.00e+00	830.00
IUUC-Bta-012980	Bos taurus	68.97	0.00e+00	776.00
IUUC-Cel-018598	Caenorhabditis elegans	25.80	1.00e-35	144.00
IUUC-Cja-019577	Callithrix jacchus	71.12	0.00e+00	825.00
IUUC-Cfa-020793	Canis familiaris	74.85	0.00e+00	751.00
IUUC-Cpo-022387	Cavia porcellus	71.78	0.00e+00	823.00
IUUC-Csa-023168	Chlorocebus sabaeus	71.29	0.00e+00	828.00
IUUC-Cho-024433	Choloepus hoffmanni	72.24	1.00e-174	606.00
IUUC-Cin-025215	Ciona intestinalis	44.22	5.00e-141	494.00
IUUC-Csv-026133	Ciona savignyi	46.58	5.00e-128	451.00
IUUC-Dre-027594	Danio rerio	70.47	0.00e+00	790.00
IUUC-Dno-029407	Dasypus novemcinctus	75.05	0.00e+00	752.00
IUUC-Dor-030961	Dipodomys ordii	75.05	0.00e+00	753.00
IUUC-Ete-032962	Echinops telfairi	69.48	0.00e+00	647.00
IUUC-Eca-033683	Equus caballus	68.97	0.00e+00	770.00
IUUC-Eeu-034515	Erinaceus europaeus	76.64	9.00e-60	224.00
IUUC-Fca-035398	Felis catus	74.90	0.00e+00	737.00
IUUC-Fal-036758	Ficedula albicollis	66.96	0.00e+00	696.00
IUUC-Gmo-039014	Gadus morhua	80.06	0.00e+00	924.00
IUUC-Gga-040575	Gallus gallus	69.52	0.00e+00	800.00
IUUC-Gac-041414	Gasterosteus aculeatus	85.85	0.00e+00	941.00
IUUC-Hsa-046272	Homo sapiens	71.29	0.00e+00	830.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	75.05	0.00e+00	754.00
IUUC-Lch-050491	Latimeria chalumnae	72.09	0.00e+00	786.00
IUUC-Loc-052758	Lepisosteus oculatus	74.33	0.00e+00	867.00
IUUC-Laf-053452	Loxodonta africana	72.86	0.00e+00	761.00
IUUC-Mcc-055820	Macaca mulatta	75.15	0.00e+00	743.00
IUUC-Meu-056726	Macropus eugenii	70.33	0.00e+00	653.00
IUUC-Mga-059937	Meleagris gallopavo	74.07	0.00e+00	749.00
IUUC-Mmr-060730	Microcebus murinus	71.17	0.00e+00	810.00
IUUC-Mdo-062771	Monodelphis domestica	70.68	0.00e+00	815.00
IUUC-Mmu-064219	Mus musculus	71.95	0.00e+00	834.00
IUUC-Mac-065495	Musa acuminata	29.93	6.00e-30	125.00
IUUC-Mpu-066796	Mustela putorius furo	75.10	0.00e+00	743.00
IUUC-Mlu-068189	Myotis lucifugus	74.30	0.00e+00	759.00
IUUC-Nle-069239	Nomascus leucogenys	70.79	0.00e+00	791.00
IUUC-Opr-070702	Ochotona princeps	62.59	2.00e-91	329.00
IUUC-Oan-073717	Ornithorhynchus anatinus	83.65	0.00e+00	695.00
IUUC-Ocu-074145	Oryctolagus cuniculus	70.96	0.00e+00	826.00
IUUC-Ogl-077929	Oryza glaberrima	39.71	3.00e-12	64.70
IUUC-Ola-087152	Oryzias latipes	86.11	0.00e+00	1038.00
IUUC-Oga-088486	Otolemur garnettii	75.48	0.00e+00	756.00
IUUC-Oar-089310	Ovis aries	74.76	0.00e+00	756.00
IUUC-Ptr-090649	Pan troglodytes	75.24	0.00e+00	762.00
IUUC-Pan-091692	Papio anubis	67.00	0.00e+00	764.00
IUUC-Psi-093064	Pelodiscus sinensis	83.00	0.00e+00	657.00
IUUC-Pma-094763	Petromyzon marinus	76.23	2.00e-96	345.00
IUUC-Ppa-095969	Physcomitrella patens	31.33	3.00e-38	153.00
IUUC-Pfo-096810	Poecilia formosa	87.23	0.00e+00	1040.00
IUUC-Pab-097859	Pongo abelii	75.15	0.00e+00	745.00
IUUC-Pop-099576	Populus trichocarpa	29.08	5.00e-26	112.00
IUUC-Pca-100344	Procavia capensis	69.52	0.00e+00	781.00
IUUC-Pva-103114	Pteropus vampyrus	52.71	7.00e-114	404.00
IUUC-Rno-105880	Rattus norvegicus	69.98	0.00e+00	786.00
IUUC-Sha-107015	Sarcophilus harrisii	76.05	0.00e+00	770.00
IUUC-Smo-109664	Selaginella moellendorffii	30.72	2.00e-33	137.00
IUUC-Sar-113397	Sorex araneus	82.04	7.00e-179	620.00
IUUC-Ssc-115988	Sus scrofa	64.54	5.00e-86	310.00
IUUC-Tgu-116717	Taeniopygia guttata	73.50	0.00e+00	751.00
IUUC-Tru-117805	Takifugu rubripes	83.49	0.00e+00	1019.00
IUUC-Tsy-119442	Tarsius syrichta	69.48	0.00e+00	664.00
IUUC-Tni-119777	Tetraodon nigroviridis	85.16	0.00e+00	723.00
IUUC-Tbe-127322	Tupaia belangeri	52.69	6.00e-77	281.00
IUUC-Ttr-128181	Tursiops truncatus	74.20	0.00e+00	760.00
IUUC-Vpa-130483	Vicugna pacos	70.38	1.00e-148	520.00
IUUC-Xtr-132614	Xenopus tropicalis	66.99	0.00e+00	674.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence