iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011540

Ensembl Protein ID

ENSAMXP00000001007.1

UniProt Accession

W5K097; W5K097_ASTMX

Genbank Protein ID

ENSAMXP00000001007

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

APWO01091847

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000000982.1	ENSAMXT00000001007.1	ENSAMXP00000001007.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.60e-11	41.9	764	819

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
            +v++lydy a   deL++ +G v++ +  +++++gW+kg  +  gk  l fP+n+ve++
   Q: 764  CTVKALYDYRAMRPDELNFCRGVVIHNV--TKESNGWWKG--DYGGKVQLyFPANYVEEI 819
           589************************9..999*******..788887766*******98 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MASRHGDHTE YKRSLIKRDL EMGIVMTVYR QKMERLTVQV IMETRQVAWT RTADKTDGVL 60
DISEIREVRP GRHSKDFERF KDNKDKQQDS KSFTIFYGNQ FVLNTLSLGA DTVDDAEKWL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAGTC GGCATGGAGA CCACACGGAG TACAAGCGGA GTCTCATAAA GCGGGACTTA 60
GAGATGGGCA TTGTAATGAC TGTGTACAGG CAGAAGATGG AGAGGCTCAC TGTACAGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028381--PLC-gamma2
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003345	Anas platyrhynchos	60.22	0.00e+00	1452.00
IUUC-Aca-004266	Anolis carolinensis	58.92	0.00e+00	1454.00
IUUC-Bta-013196	Bos taurus	59.14	0.00e+00	1395.00
IUUC-Cpo-021890	Cavia porcellus	58.17	0.00e+00	1432.00
IUUC-Csa-024233	Chlorocebus sabaeus	58.76	0.00e+00	1449.00
IUUC-Dre-028650	Danio rerio	76.37	0.00e+00	1870.00
IUUC-Dno-028871	Dasypus novemcinctus	58.71	0.00e+00	1411.00
IUUC-Eca-033458	Equus caballus	59.08	0.00e+00	1447.00
IUUC-Eeu-035329	Erinaceus europaeus	57.71	0.00e+00	1380.00
IUUC-Fal-037390	Ficedula albicollis	59.70	0.00e+00	1464.00
IUUC-Gga-040918	Gallus gallus	59.87	0.00e+00	1459.00
IUUC-Ggo-045625	Gorilla gorilla	57.53	0.00e+00	1410.00
IUUC-Hsa-046129	Homo sapiens	58.70	0.00e+00	1445.00
IUUC-Loc-052025	Lepisosteus oculatus	68.99	0.00e+00	1678.00
IUUC-Mcc-054831	Macaca mulatta	58.93	0.00e+00	1445.00
IUUC-Mga-059368	Meleagris gallopavo	60.20	0.00e+00	1443.00
IUUC-Mmr-060898	Microcebus murinus	56.32	0.00e+00	1303.00
IUUC-Mmu-064334	Mus musculus	58.89	0.00e+00	1437.00
IUUC-Mlu-067230	Myotis lucifugus	58.98	0.00e+00	1444.00
IUUC-Nle-069318	Nomascus leucogenys	54.90	0.00e+00	1312.00
IUUC-Opr-070718	Ochotona princeps	53.90	0.00e+00	696.00
IUUC-Ocu-073814	Oryctolagus cuniculus	58.58	0.00e+00	1432.00
IUUC-Ola-086501	Oryzias latipes	69.15	0.00e+00	1706.00
IUUC-Oar-089556	Ovis aries	58.56	0.00e+00	1390.00
IUUC-Ptr-091001	Pan troglodytes	58.53	0.00e+00	1444.00
IUUC-Pan-092744	Papio anubis	58.84	0.00e+00	1448.00
IUUC-Psi-093987	Pelodiscus sinensis	59.48	0.00e+00	1455.00
IUUC-Pfo-096249	Poecilia formosa	70.61	0.00e+00	1731.00
IUUC-Pab-098268	Pongo abelii	57.90	0.00e+00	1415.00
IUUC-Pva-102939	Pteropus vampyrus	57.58	0.00e+00	1337.00
IUUC-Ssc-115308	Sus scrofa	56.11	0.00e+00	1334.00
IUUC-Tgu-116811	Taeniopygia guttata	59.53	0.00e+00	1454.00
IUUC-Tru-117536	Takifugu rubripes	66.94	0.00e+00	1635.00
IUUC-Tsy-119139	Tarsius syrichta	54.48	9.00e-177	614.00
IUUC-Ttr-128392	Tursiops truncatus	56.63	0.00e+00	1368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence