iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061825

UUCD1 version

UUC-MoD-01033

Ensembl Protein ID

ENSMODP00000008127.1

UniProt Accession

F7BV64; F7BV64_MONDO

Protein Name

Uncharacterized protein

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000006549.1	ENSMODT00000008291.1	ENSMODP00000008127.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.70e-48	161.8	15	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 15   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 103
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++ 
   Q: 104  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKD 153
           999*9****************************************99886 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKA 60
RLKFPIDYPY SPPAFRFLTK MWHPNIYETG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCGGC CGCTGGTGCC CAGCTCGCAG AAGGCGCTGC TCCTGGAGCT CAAGGGACTG 60
CAGGAGGAGC CGGTCGAGGG CTTCCGGGTG ACCCTGGTGG ACGAGGGCGA CCTGTACAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

KEGG

mdo:100016923

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	99.51	2.00e-120	424.00
IUUC-Ame-011425	Astyanax mexicanus	90.05	6.00e-109	386.00
IUUC-Bta-012516	Bos taurus	99.03	4.00e-120	423.00
IUUC-Cja-018852	Callithrix jacchus	88.60	4.00e-103	367.00
IUUC-Cfa-020203	Canis familiaris	97.77	3.00e-120	424.00
IUUC-Cpo-022139	Cavia porcellus	96.12	2.00e-116	411.00
IUUC-Csa-023371	Chlorocebus sabaeus	97.77	2.00e-120	424.00
IUUC-Dre-028367	Danio rerio	89.55	1.00e-108	385.00
IUUC-Dor-030875	Dipodomys ordii	98.22	4.00e-121	426.00
IUUC-Fca-035832	Felis catus	98.65	2.00e-84	304.00
IUUC-Gmo-039414	Gadus morhua	90.55	6.00e-110	389.00
IUUC-Gga-040694	Gallus gallus	97.03	5.00e-123	433.00
IUUC-Gac-042485	Gasterosteus aculeatus	89.05	2.00e-109	387.00
IUUC-Ggo-044806	Gorilla gorilla	98.21	1.00e-120	425.00
IUUC-Hsa-046245	Homo sapiens	98.21	2.00e-120	424.00
IUUC-Lch-049845	Latimeria chalumnae	90.55	7.00e-110	389.00
IUUC-Loc-052932	Lepisosteus oculatus	92.04	1.00e-111	395.00
IUUC-Mcc-054665	Macaca mulatta	94.20	2.00e-113	400.00
IUUC-Mga-060075	Meleagris gallopavo	96.61	9.00e-123	432.00
IUUC-Mmr-061165	Microcebus murinus	99.51	3.00e-120	424.00
IUUC-Mmu-064168	Mus musculus	99.51	2.00e-120	424.00
IUUC-Mpu-066009	Mustela putorius furo	99.51	6.00e-120	422.00
IUUC-Opr-070826	Ochotona princeps	92.09	2.00e-107	381.00
IUUC-Ont-071745	Oreochromis niloticus	90.64	4.00e-111	393.00
IUUC-Oan-073287	Ornithorhynchus anatinus	90.68	1.00e-117	414.00
IUUC-Ocu-074902	Oryctolagus cuniculus	95.15	6.00e-116	409.00
IUUC-Oga-088845	Otolemur garnettii	99.03	1.00e-119	421.00
IUUC-Ptr-090916	Pan troglodytes	98.54	4.00e-117	413.00
IUUC-Pan-092577	Papio anubis	97.77	2.00e-120	424.00
IUUC-Psi-093039	Pelodiscus sinensis	96.63	5.00e-89	319.00
IUUC-Pfo-096435	Poecilia formosa	90.05	3.00e-110	390.00
IUUC-Pab-098200	Pongo abelii	98.05	2.00e-109	387.00
IUUC-Pca-100169	Procavia capensis	86.43	1.00e-65	242.00
IUUC-Pva-102875	Pteropus vampyrus	96.97	2.00e-84	304.00
IUUC-Rno-106079	Rattus norvegicus	99.51	2.00e-120	424.00
IUUC-Ssc-115699	Sus scrofa	85.03	2.00e-87	314.00
IUUC-Tgu-117466	Taeniopygia guttata	94.92	9.00e-121	425.00
IUUC-Xtr-132285	Xenopus tropicalis	91.18	7.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence