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Tag Content
UUCD2 ID IUUC-Dre-027388
UUCD1 version UUC-DaR-00127
Ensembl Protein ID ENSDARP00000124228.1
UniProt Accession A9CP01; A9CP01_DANRE
Genbank Protein ID BAF95684.1
Protein Name Kelch-like ECH-associated protein 1b; Nrf2-associated protein keap1b
Genbank Nucleotide ID CU693486
Gene Name keap1b
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000074634.4 ENSDART00000148974.2 ENSDARP00000124228.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 1.60e-14 54.9 50 121
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 9.10e-10 37.7 155 185
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 1    aDvilvv.....g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l v     +  + f ahk+vLa+sS+vF+a+f+++l+e    + v i+++ p+v+  l++F Yt +++ 
   Q: 50   CDVTLRVrycplDtHVDFVAHKVVLASSSPVFRAMFTNGLKECG-MEVVPIEGIHPKVMGRLIEFAYTASISV 121
           89999998887745999**************************9.***********************98875 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi +fA++ +c++L+++a+++i  +F
   Q: 155  PSNAIGIASFAEQIGCTELHQKAREYIYMNF 185
           89****************************9 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MLAAAGMTEC KAEVTPSASN GHRVFSYTLE SHTAAAFAIM NELRRERQLC DVTLRVRYCP 60
LDTHVDFVAH KVVLASSSPV FRAMFTNGLK ECGMEVVPIE GIHPKVMGRL IEFAYTASIS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-027388|E3,BTB_3-box|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTTAGTCACG CTGAGTTTCT GCTTTCAGTG GGTATGATAC ACACACAAGT ACACACACTC 60
ACATACACAC AGAAGTGCTC ACACACACAC ACACACACAC AGAGAGAGAG AGAGAGTGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027388|E3,BTB_3-box|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0008134--F:transcription factor binding
GO:0071379--P:cellular response to prostaglandin stimulus
GO:0071466--P:cellular response to xenobiotic stimulus
GO:0042994--P:cytoplasmic sequestering of transcription factor
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
KEGG dre:100003679
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001377 Ailuropoda melanoleuca 77.59 0.00e+00 954.00
IUUC-Aca-005389 Anolis carolinensis 77.42 0.00e+00 949.00
IUUC-Ame-010749 Astyanax mexicanus 90.80 0.00e+00 1123.00
IUUC-Bta-013505 Bos taurus 77.08 0.00e+00 947.00
IUUC-Cja-018823 Callithrix jacchus 76.78 0.00e+00 939.00
IUUC-Cfa-021202 Canis familiaris 77.59 0.00e+00 954.00
IUUC-Cpo-021830 Cavia porcellus 75.61 0.00e+00 655.00
IUUC-Csa-023728 Chlorocebus sabaeus 77.08 0.00e+00 944.00
IUUC-Cin-025195 Ciona intestinalis 53.87 0.00e+00 651.00
IUUC-Csv-026155 Ciona savignyi 51.83 2.00e-173 602.00
IUUC-Dno-029066 Dasypus novemcinctus 70.77 0.00e+00 832.00
IUUC-Dor-030674 Dipodomys ordii 77.02 0.00e+00 666.00
IUUC-Dme-032165 Drosophila melanogaster 49.29 3.00e-157 548.00
IUUC-Eca-034381 Equus caballus 75.04 0.00e+00 922.00
IUUC-Eeu-034791 Erinaceus europaeus 78.05 0.00e+00 646.00
IUUC-Fca-036067 Felis catus 77.42 0.00e+00 951.00
IUUC-Gmo-039691 Gadus morhua 86.71 0.00e+00 1065.00
IUUC-Gga-040266 Gallus gallus 75.13 0.00e+00 902.00
IUUC-Gac-041866 Gasterosteus aculeatus 86.43 0.00e+00 1061.00
IUUC-Ggo-044719 Gorilla gorilla 77.25 0.00e+00 948.00
IUUC-Hsa-046255 Homo sapiens 77.25 0.00e+00 948.00
IUUC-Itr-048457 Ictidomys tridecemlineatus 77.08 0.00e+00 949.00
IUUC-Lch-049646 Latimeria chalumnae 80.52 0.00e+00 983.00
IUUC-Laf-054579 Loxodonta africana 77.08 0.00e+00 948.00
IUUC-Mcc-055315 Macaca mulatta 77.08 0.00e+00 944.00
IUUC-Meu-056288 Macropus eugenii 73.02 0.00e+00 881.00
IUUC-Mmr-061639 Microcebus murinus 77.12 0.00e+00 950.00
IUUC-Mdo-062072 Monodelphis domestica 78.27 0.00e+00 961.00
IUUC-Mmu-063622 Mus musculus 76.40 0.00e+00 942.00
IUUC-Mpu-066737 Mustela putorius furo 78.07 0.00e+00 931.00
IUUC-Mlu-068173 Myotis lucifugus 77.25 0.00e+00 946.00
IUUC-Nle-069336 Nomascus leucogenys 49.15 5.00e-139 487.00
IUUC-Opr-070432 Ochotona princeps 77.93 0.00e+00 956.00
IUUC-Ont-072160 Oreochromis niloticus 85.57 0.00e+00 1054.00
IUUC-Oan-072691 Ornithorhynchus anatinus 71.14 0.00e+00 843.00
IUUC-Ocu-073798 Oryctolagus cuniculus 77.29 0.00e+00 947.00
IUUC-Obr-076181 Oryza brachyantha 33.46 6.00e-37 149.00
IUUC-Ola-086367 Oryzias latipes 82.00 0.00e+00 1005.00
IUUC-Oga-088231 Otolemur garnettii 77.08 0.00e+00 947.00
IUUC-Oar-089227 Ovis aries 75.89 0.00e+00 926.00
IUUC-Ptr-091460 Pan troglodytes 77.25 0.00e+00 948.00
IUUC-Pan-092713 Papio anubis 77.08 0.00e+00 944.00
IUUC-Pfo-096468 Poecilia formosa 87.46 0.00e+00 1052.00
IUUC-Pab-098357 Pongo abelii 77.25 0.00e+00 948.00
IUUC-Pca-100837 Procavia capensis 76.74 0.00e+00 937.00
IUUC-Pva-103249 Pteropus vampyrus 74.70 0.00e+00 892.00
IUUC-Rno-106086 Rattus norvegicus 75.89 0.00e+00 932.00
IUUC-Sha-107245 Sarcophilus harrisii 78.10 0.00e+00 961.00
IUUC-Sar-112985 Sorex araneus 77.08 0.00e+00 950.00
IUUC-Ssc-115756 Sus scrofa 77.25 0.00e+00 950.00
IUUC-Tgu-116838 Taeniopygia guttata 55.76 1.00e-119 422.00
IUUC-Tru-117644 Takifugu rubripes 86.84 0.00e+00 1071.00
IUUC-Tni-120245 Tetraodon nigroviridis 87.29 0.00e+00 1070.00
IUUC-Tbe-127472 Tupaia belangeri 77.37 3.00e-116 412.00
IUUC-Ttr-128953 Tursiops truncatus 76.31 5.00e-142 498.00
IUUC-Vpa-130683 Vicugna pacos 75.56 0.00e+00 838.00
IUUC-Xtr-132827 Xenopus tropicalis 72.57 0.00e+00 899.00
Created Date 25-Jun-2017

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