iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111785

Ensembl Protein ID

Solyc12g096590.1.1

UniProt Accession

K4DHD2; K4DHD2_SOLLC

Protein Name

6,7-dimethyl-8-ribityllumazine synthase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc12g096590.1	Solyc12g096590.1.1	Solyc12g096590.1.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	31.88	3.20e-01	33.10	IUUC-Hsa-046110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Solanum lycopersicum

Functional Description
(View)

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Protein Sequence
(Fasta)

MAASAFGQCS LLPRTVSLNP QQSHRQLCSL SFHRQTVNSS LPALSFTQSI GFGSAIERHC 60
VDRNGSDLFK TDAVRQLNGS VISAKGHRFA IVVARFNDLI TKKLLEGALE TFKNYSVREE 120

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Nucleotide Sequence
(Fasta)

ATGGCGGCTT CAGCTTTCGG ACAGTGTAGT CTTCTTCCTC GTACAGTATC TTTGAATCCT 60
CAGCAGTCTC ATCGTCAGCT CTGCAGTTTG TCTTTCCATA GACAAACTGT AAATTCTTCA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0686--Riboflavin biosynthesis
KW-0808--Transferase

Interpro

IPR002180--DMRL_synthase

Pfam

PF00885--DMRL_synthase

Gene Ontology

GO:0009570--C:chloroplast stroma
GO:0009349--C:riboflavin synthase complex
GO:0000906--F:6,7-dimethyl-8-ribityllumazine synthase activity
GO:0016740--F:transferase activity
GO:0009231--P:riboflavin biosynthetic process

KEGG

sly:101251867

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007928	Ashbya gossypii	30.19	3.20e+00	26.20
IUUC-Cfa-020153	Canis familiaris	31.88	2.10e-02	33.50
IUUC-Csa-023365	Chlorocebus sabaeus	31.88	2.10e-02	33.50
IUUC-Dno-029864	Dasypus novemcinctus	31.88	2.60e-02	33.10
IUUC-Dor-030217	Dipodomys ordii	31.88	2.00e-02	33.10
IUUC-Fca-035677	Felis catus	31.88	2.30e-02	33.10
IUUC-Ggo-045243	Gorilla gorilla	31.88	2.00e-02	33.50
IUUC-Hsa-046110	Homo sapiens	31.88	2.00e-02	33.50
IUUC-Itr-048330	Ictidomys tridecemlineatus	31.88	2.00e-02	33.50
IUUC-Lch-049976	Latimeria chalumnae	23.00	8.00e-04	38.10
IUUC-Mcc-055423	Macaca mulatta	31.88	2.00e-02	33.50
IUUC-Mmr-061735	Microcebus murinus	31.88	2.00e-02	33.50
IUUC-Mdo-062840	Monodelphis domestica	32.26	1.50e-01	30.40
IUUC-Mmu-063429	Mus musculus	31.88	1.90e-02	33.50
IUUC-Mpu-066580	Mustela putorius furo	31.88	2.00e-02	33.50
IUUC-Nle-069106	Nomascus leucogenys	31.88	1.90e-02	33.50
IUUC-Ome-081362	Oryza meridionalis	65.85	2.00e-35	142.00
IUUC-Oni-082277	Oryza nivara	65.85	3.00e-35	142.00
IUUC-Oga-088405	Otolemur garnettii	31.88	2.40e-02	33.10
IUUC-Ptr-091612	Pan troglodytes	31.88	2.00e-02	33.50
IUUC-Pan-091919	Papio anubis	31.88	2.20e-02	33.50
IUUC-Pfo-097298	Poecilia formosa	34.78	1.10e-01	32.00
IUUC-Pab-098642	Pongo abelii	31.88	2.00e-02	33.50
IUUC-Pva-102937	Pteropus vampyrus	31.88	2.10e-02	33.50
IUUC-Rno-105343	Rattus norvegicus	31.88	2.00e-02	33.50
IUUC-Ssc-115265	Sus scrofa	31.88	2.30e-02	33.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence