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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063746
Ensembl Protein ID ENSMUSP00000130854.1
UniProt Accession O88746; Q3V4C6; Q9D120; TOM1_MOUSE
Genbank Protein ID CAA07361.1; BAE43160.1; BAC25932.1; AAH21633.1
Protein Name Target of Myb protein 1
Genbank Nucleotide ID AJ006972; AK004063; AK028398; BC021633
Gene Name Tom1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000042870.15 ENSMUST00000165630.2 ENSMUSP00000130854.1
ENSMUSG00000042870.15 ENSMUST00000212564.1 ENSMUSP00000148584.1
ENSMUSG00000042870.15 ENSMUST00000212299.1 ENSMUSP00000148670.1
ENSMUSG00000042870.15 ENSMUST00000078847.12 ENSMUSP00000077891.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/GAT GAT 14563850
UBD/Alpha-Helix/VHS VHS 14563850
Classification
Family E-value Score Start End
UBD/Alpha-Helix/VHS 2.70e-51 174.1 20 152
UBD/Alpha-Helix/GAT 3.10e-28 99.5 214 302
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/VHS
   S: 1    atselvtsedwelileicdliqetkegakdalralrkri.nnknphvalraLtlLdscvsnCgkkfhvevaskdllee..lrell.kne 85
           at+ +++sedw+l++eicd+i+et+eg+kda+ra++kri +nkn+h++++aLt+L++cv+nCg++fhv+va++d++e+  +r++l kn+
   Q: 20   ATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRImGNKNFHEVMLALTVLETCVKNCGHRFHVLVANQDFVENvlVRTILpKNN 108
           68999**********************************9**************************************999******** PP
   S: 86   nepkvieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           +++ v++K+++li+sWad+++++p+l+++va++++l+++Glefp
   Q: 109  PPTIVHDKVLNLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFP 152
           *******************************************8 PP
   

   UBD/Alpha-Helix/GAT
   S: 38   aekikkliseleevksnvkllnemlselspegeepednellqelyetckaarpkllklieeeedndellaellkanDelnqvlnkykql 126
            e+i+kl+sele+v++nv++++eml+el+p++ ep+d ellqel++tc+a+++++l+li +  +n++l++ell++nD+ln+v+++++++
   Q: 214  PEQIGKLRSELEMVSGNVRVMSEMLTELVPTQVEPADLELLQELNRTCRAMQQRILELIPR-ISNEQLTEELLMINDNLNNVFLRHERF 301
           589**********************************************************.*************************99 PP
   S: 127  k 127
           +
   Q: 302  E 302
           7 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Interacts with ZFYVE16; interaction is required to target it to endosomes.
 Interacts with ZFYVE16; interaction is required to target it to endosomes.
Protein Sequence
(Fasta)
MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA FRAVKKRIMG 60
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA NQDFVENVLV RTILPKNNPP TIVHDKVLNL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063746|UBD,GAT;UBD,VHS|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGGCGGGTC GGCGGCGCCG GCGGTTGCTG TCACCTGATT CTGGGAGCTG GTGGCAGCGG 60
TAGCCGCGGC AATGGACTTT CTCCTGGGAA ATCCGTTCAG CTCTCCGGTG GGACAACGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063746|UBD,GAT;UBD,VHS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR014645--TOM1
IPR002014--VHS_dom
PROSITE

PS50909--GAT
PS50179--VHS
Pfam

PF03127--GAT
PF00790--VHS
SMART

SM00288--VHS
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0030276--F:clathrin binding
GO:0006886--P:intracellular protein transport
KEGG mmu:21968
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001372 Ailuropoda melanoleuca 86.63 0.00e+00 862.00
IUUC-Apl-004197 Anas platyrhynchos 71.63 0.00e+00 664.00
IUUC-Aca-005277 Anolis carolinensis 71.31 0.00e+00 647.00
IUUC-Bta-013410 Bos taurus 89.23 0.00e+00 872.00
IUUC-Cel-018158 Caenorhabditis elegans 49.28 4.00e-89 322.00
IUUC-Cja-018944 Callithrix jacchus 83.77 0.00e+00 814.00
IUUC-Cfa-021024 Canis familiaris 87.80 0.00e+00 852.00
IUUC-Cpo-021418 Cavia porcellus 83.16 0.00e+00 803.00
IUUC-Csa-023653 Chlorocebus sabaeus 86.47 0.00e+00 862.00
IUUC-Cne-026931 Cryptococcus neoformans 26.97 1.00e-14 74.70
IUUC-Dno-029610 Dasypus novemcinctus 87.78 0.00e+00 701.00
IUUC-Dor-030925 Dipodomys ordii 78.66 0.00e+00 750.00
IUUC-Eca-034207 Equus caballus 90.24 0.00e+00 867.00
IUUC-Eeu-035025 Erinaceus europaeus 73.33 2.00e-122 432.00
IUUC-Fca-036407 Felis catus 87.58 0.00e+00 807.00
IUUC-Fal-036809 Ficedula albicollis 72.76 0.00e+00 677.00
IUUC-Gga-040357 Gallus gallus 72.69 0.00e+00 719.00
IUUC-Ggo-044454 Gorilla gorilla 88.20 0.00e+00 871.00
IUUC-Hsa-046652 Homo sapiens 89.43 0.00e+00 876.00
IUUC-Itr-049028 Ictidomys tridecemlineatus 84.50 0.00e+00 856.00
IUUC-Laf-054231 Loxodonta africana 86.74 0.00e+00 669.00
IUUC-Mcc-055475 Macaca mulatta 89.84 0.00e+00 876.00
IUUC-Meu-056002 Macropus eugenii 64.95 4.00e-152 530.00
IUUC-Mla-058817 Melampsora laricipopulina 24.85 4.00e-19 89.40
IUUC-Mga-059199 Meleagris gallopavo 70.11 0.00e+00 655.00
IUUC-Mmr-061193 Microcebus murinus 89.66 0.00e+00 817.00
IUUC-Mdo-062456 Monodelphis domestica 78.38 0.00e+00 701.00
IUUC-Mpu-066772 Mustela putorius furo 88.03 0.00e+00 885.00
IUUC-Mlu-067475 Myotis lucifugus 84.02 0.00e+00 684.00
IUUC-Nle-068998 Nomascus leucogenys 86.23 0.00e+00 843.00
IUUC-Oan-073103 Ornithorhynchus anatinus 73.19 0.00e+00 723.00
IUUC-Ocu-073922 Oryctolagus cuniculus 82.78 0.00e+00 767.00
IUUC-Oga-089050 Otolemur garnettii 80.12 0.00e+00 773.00
IUUC-Oar-090246 Ovis aries 84.91 0.00e+00 816.00
IUUC-Ptr-090714 Pan troglodytes 88.84 0.00e+00 867.00
IUUC-Pan-092875 Papio anubis 89.84 0.00e+00 876.00
IUUC-Psi-094051 Pelodiscus sinensis 71.62 0.00e+00 694.00
IUUC-Pab-098291 Pongo abelii 88.24 0.00e+00 801.00
IUUC-Pca-100907 Procavia capensis 80.69 0.00e+00 738.00
IUUC-Pva-102610 Pteropus vampyrus 80.49 0.00e+00 778.00
IUUC-Pgr-103677 Puccinia graminis 24.82 4.00e-20 92.80
IUUC-Rno-105809 Rattus norvegicus 96.14 0.00e+00 942.00
IUUC-Sce-106195 Saccharomyces cerevisiae 25.85 3.00e-17 83.60
IUUC-Sha-107255 Sarcophilus harrisii 80.04 0.00e+00 691.00
IUUC-Ssl-108413 Sclerotinia sclerotiorum 39.04 7.00e-22 96.30
IUUC-Sre-115232 Sporisorium reilianum 25.23 1.00e-17 84.70
IUUC-Tgu-117517 Taeniopygia guttata 73.85 0.00e+00 716.00
IUUC-Tni-120701 Tetraodon nigroviridis 51.31 2.00e-144 505.00
IUUC-Ttr-128710 Tursiops truncatus 81.54 0.00e+00 746.00
IUUC-Uma-129380 Ustilago maydis 25.73 2.00e-14 74.30
IUUC-Vpa-130381 Vicugna pacos 69.10 1.00e-104 373.00
Created Date 25-Jun-2017

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