iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007997

Ensembl Protein ID

AAS53591

UniProt Accession

Q753V5; RAD5_ASHGO

Genbank Protein ID

AAS53591.2

Protein Name

DNA repair protein RAD5

Genbank Nucleotide ID

AE016819

Gene Name

RAD5; AFR220W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFR220W	AAS53591	AAS53591

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.90e-06	24.2	832	880

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC ++        +++++CgH f+++Cl  + + +n++  e +CP Cr
   Q: 832  CSICTCEAisplTS-VVFTRCGHPFCESCLLEYIQFQNKKGSETICPNCR 880
           99**7766333244.778************999777777999999****8 PP

Organism

Ashbya gossypii

Functional Description
(View)

Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

Protein Sequence
(Fasta)

MQRTGDGERP RFFQQDLDVI PDDKGSDLFI QTAEGPDGHV DDEVIEDKTR FITNLKEVLG 60
ALPDDILEGY WNSYGASKDG LSKAIQQHFE GKETKGCSDA HDDLNTETQN SQNTIVNGHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAACGAA CTGGTGATGG TGAAAGGCCA CGGTTCTTCC AGCAGGATTT AGATGTAATA 60
CCTGACGATA AAGGTTCTGA CCTATTCATA CAAACAGCAG AAGGCCCGGA TGGCCATGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N
PF13639--zf-RING_2

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN
SM00184--RING

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0008094--F:DNA-dependent ATPase activity
GO:0000400--F:four-way junction DNA binding
GO:0009378--F:four-way junction helicase activity
GO:0000403--F:Y-form DNA binding
GO:0008270--F:zinc ion binding
GO:0006302--P:double-strand break repair
GO:0042276--P:error-prone translesion synthesis
GO:0010994--P:free ubiquitin chain polymerization
GO:0000209--P:protein polyubiquitination

KEGG

ago:AGOS_AFR220W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	33.56	3.00e-102	363.00
IUUC-Aml-001237	Ailuropoda melanoleuca	33.56	4.00e-75	274.00
IUUC-Atr-003139	Amborella trichopoda	30.44	2.00e-109	388.00
IUUC-Aca-004994	Anolis carolinensis	34.88	3.00e-79	288.00
IUUC-Aly-006331	Arabidopsis lyrata	29.17	2.00e-102	364.00
IUUC-Ath-007079	Arabidopsis thaliana	33.29	6.00e-105	373.00
IUUC-Acl-008022	Aspergillus clavatus	33.21	1.00e-137	481.00
IUUC-Afl-008514	Aspergillus flavus	32.60	6.00e-137	479.00
IUUC-Afu-009055	Aspergillus fumigatus	32.10	8.00e-139	486.00
IUUC-Ani-009340	Aspergillus nidulans	31.89	7.00e-138	483.00
IUUC-Ang-009785	Aspergillus niger	33.91	3.00e-140	491.00
IUUC-Aor-010158	Aspergillus oryzae	32.36	4.00e-137	480.00
IUUC-Ate-010536	Aspergillus terreus	31.43	2.00e-127	447.00
IUUC-Ame-011743	Astyanax mexicanus	33.33	4.00e-74	270.00
IUUC-Bgr-012147	Blumeria graminis	32.12	7.00e-143	499.00
IUUC-Bta-013391	Bos taurus	34.12	5.00e-83	300.00
IUUC-Bci-013741	Botrytis cinerea	33.00	3.00e-134	471.00
IUUC-Bdi-014646	Brachypodium distachyon	30.63	1.00e-107	382.00
IUUC-Bol-015995	Brassica oleracea	33.24	1.00e-104	372.00
IUUC-Bra-017004	Brassica rapa	33.83	8.00e-106	376.00
IUUC-Cja-019685	Callithrix jacchus	33.78	4.00e-83	300.00
IUUC-Cfa-020485	Canis familiaris	33.28	1.00e-75	275.00
IUUC-Cpo-021361	Cavia porcellus	34.33	3.00e-74	270.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	24.80	4.00e-42	165.00
IUUC-Csa-023894	Chlorocebus sabaeus	33.61	2.00e-82	298.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	37.15	5.00e-138	483.00
IUUC-Cne-026886	Cryptococcus neoformans	31.44	6.00e-106	377.00
IUUC-Cme-027110	Cyanidioschyzon merolae	28.40	1.00e-91	329.00
IUUC-Dre-027867	Danio rerio	35.14	3.00e-86	310.00
IUUC-Dno-029517	Dasypus novemcinctus	34.34	3.00e-74	271.00
IUUC-Dor-030590	Dipodomys ordii	32.11	4.00e-35	141.00
IUUC-Dse-031471	Dothistroma septosporum	32.87	8.00e-139	486.00
IUUC-Ete-032421	Echinops telfairi	29.77	8.00e-57	213.00
IUUC-Eca-034058	Equus caballus	34.12	4.00e-71	260.00
IUUC-Fca-035390	Felis catus	33.28	6.00e-75	273.00
IUUC-Fox-038039	Fusarium oxysporum	37.52	3.00e-134	470.00
IUUC-Fso-038179	Fusarium solani	32.77	3.00e-140	491.00
IUUC-Gmo-038544	Gadus morhua	32.26	2.00e-80	291.00
IUUC-Ggr-039735	Gaeumannomyces graminis	32.74	5.00e-137	480.00
IUUC-Gac-042401	Gasterosteus aculeatus	32.26	5.00e-83	300.00
IUUC-Gma-042995	Glycine max	29.51	2.00e-104	371.00
IUUC-Ggo-045628	Gorilla gorilla	33.78	6.00e-83	300.00
IUUC-Hsa-045930	Homo sapiens	33.78	6.00e-83	300.00
IUUC-Hvu-047747	Hordeum vulgare	33.47	1.00e-102	365.00
IUUC-Itr-048493	Ictidomys tridecemlineatus	34.05	5.00e-80	290.00
IUUC-Kpa-049087	Komagataella pastoris	39.18	0.00e+00	672.00
IUUC-Lch-050617	Latimeria chalumnae	32.26	1.00e-78	285.00
IUUC-Lpe-051123	Leersia perrieri	33.33	2.00e-103	368.00
IUUC-Loc-052785	Lepisosteus oculatus	35.04	3.00e-84	304.00
IUUC-Lma-052956	Leptosphaeria maculans	32.90	3.00e-140	490.00
IUUC-Laf-054309	Loxodonta africana	33.99	2.00e-75	275.00
IUUC-Mcc-055493	Macaca mulatta	33.78	2.00e-83	301.00
IUUC-Mor-057210	Magnaporthe oryzae	34.01	6.00e-141	493.00
IUUC-Mpo-057407	Magnaporthe poae	32.84	8.00e-140	489.00
IUUC-Mtr-058194	Medicago truncatula	29.72	8.00e-96	343.00
IUUC-Mla-058867	Melampsora laricipopulina	37.28	8.00e-69	253.00
IUUC-Mvi-060322	Microbotryum violaceum	28.36	1.00e-75	276.00
IUUC-Mmr-061043	Microcebus murinus	34.53	1.00e-76	279.00
IUUC-Mmu-064338	Mus musculus	34.05	3.00e-79	288.00
IUUC-Mac-064548	Musa acuminata	29.27	5.00e-93	333.00
IUUC-Mpu-066781	Mustela putorius furo	33.17	5.00e-75	273.00
IUUC-Mlu-068076	Myotis lucifugus	34.41	3.00e-75	275.00
IUUC-Nfi-068354	Neosartorya fischeri	32.55	9.00e-140	489.00
IUUC-Ncr-068844	Neurospora crassa	33.63	4.00e-141	493.00
IUUC-Nle-069947	Nomascus leucogenys	33.61	2.00e-82	298.00
IUUC-Ont-071782	Oreochromis niloticus	32.43	2.00e-83	301.00
IUUC-Oan-073331	Ornithorhynchus anatinus	31.74	7.00e-72	263.00
IUUC-Ocu-074705	Oryctolagus cuniculus	34.12	4.00e-81	294.00
IUUC-Oba-075316	Oryza barthii	28.79	5.00e-98	350.00
IUUC-Obr-076403	Oryza brachyantha	31.02	1.00e-103	369.00
IUUC-Ogl-077573	Oryza glaberrima	31.43	9.00e-106	375.00
IUUC-Ogu-078083	Oryza glumaepatula	29.00	8.00e-101	359.00
IUUC-Oin-079146	Oryza indica	31.43	5.00e-106	377.00
IUUC-Olo-080615	Oryza longistaminata	29.79	5.00e-105	373.00
IUUC-Ome-081448	Oryza meridionalis	30.23	2.00e-92	331.00
IUUC-Oni-082773	Oryza nivara	29.04	4.00e-100	357.00
IUUC-Opu-083675	Oryza punctata	29.60	2.00e-104	371.00
IUUC-Oru-084543	Oryza rufipogon	32.27	9.00e-100	356.00
IUUC-Osa-085686	Oryza sativa	33.61	5.00e-103	366.00
IUUC-Ola-086830	Oryzias latipes	31.69	1.00e-76	278.00
IUUC-Oga-088120	Otolemur garnettii	34.12	8.00e-70	256.00
IUUC-Oar-089293	Ovis aries	34.41	5.00e-83	300.00
IUUC-Ptr-091418	Pan troglodytes	33.78	1.00e-82	299.00
IUUC-Pan-092579	Papio anubis	30.81	2.00e-42	165.00
IUUC-Psi-093626	Pelodiscus sinensis	33.27	1.00e-81	295.00
IUUC-Pno-094916	Phaeosphaeria nodorum	34.74	4.00e-145	506.00
IUUC-Ppa-095877	Physcomitrella patens	34.72	9.00e-106	376.00
IUUC-Pfo-096540	Poecilia formosa	31.96	2.00e-80	291.00
IUUC-Pab-098010	Pongo abelii	33.78	1.00e-82	299.00
IUUC-Pop-099537	Populus trichocarpa	31.99	1.00e-107	382.00
IUUC-Pca-100648	Procavia capensis	33.05	1.00e-77	282.00
IUUC-Ppe-101820	Prunus persica	29.16	5.00e-99	353.00
IUUC-Pva-102896	Pteropus vampyrus	33.33	1.00e-67	249.00
IUUC-Pgr-103454	Puccinia graminis	32.55	9.00e-105	373.00
IUUC-Ptt-103829	Puccinia triticina	26.92	1.00e-81	296.00
IUUC-Pte-104242	Pyrenophora teres	31.58	2.00e-140	491.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	32.90	1.00e-139	488.00
IUUC-Rno-106130	Rattus norvegicus	33.57	4.00e-79	287.00
IUUC-Sce-106396	Saccharomyces cerevisiae	47.36	0.00e+00	941.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	36.28	2.00e-148	518.00
IUUC-Spo-108026	Schizosaccharomyces pombe	34.25	1.00e-145	508.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	33.53	5.00e-136	476.00
IUUC-Sit-110076	Setaria italica	30.99	2.00e-108	384.00
IUUC-Sly-111031	Solanum lycopersicum	30.28	4.00e-107	380.00
IUUC-Stu-112600	Solanum tuberosum	33.24	2.00e-107	381.00
IUUC-Sar-113719	Sorex araneus	35.13	2.00e-84	305.00
IUUC-Sbi-113927	Sorghum bicolor	31.25	4.00e-108	384.00
IUUC-Sre-115131	Sporisorium reilianum	34.06	2.00e-69	256.00
IUUC-Ssc-116186	Sus scrofa	34.59	7.00e-82	296.00
IUUC-Tru-117768	Takifugu rubripes	32.68	9.00e-78	283.00
IUUC-Tsy-118957	Tarsius syrichta	34.42	2.00e-77	282.00
IUUC-Tni-120618	Tetraodon nigroviridis	34.10	2.00e-89	322.00
IUUC-Tca-121137	Theobroma cacao	29.89	2.00e-106	378.00
IUUC-Tre-121896	Trichoderma reesei	31.62	4.00e-135	473.00
IUUC-Tvi-122597	Trichoderma virens	31.11	1.00e-135	475.00
IUUC-Tae-124722	Triticum aestivum	31.62	8.00e-106	376.00
IUUC-Tur-125999	Triticum urartu	33.75	3.00e-103	367.00
IUUC-Tme-126953	Tuber melanosporum	32.22	2.00e-132	464.00
IUUC-Ttr-128243	Tursiops truncatus	31.92	4.00e-39	154.00
IUUC-Uma-129629	Ustilago maydis	31.47	2.00e-101	362.00
IUUC-Vda-129849	Verticillium dahliae	35.33	9.00e-118	416.00
IUUC-Vpa-130672	Vicugna pacos	34.59	2.00e-74	271.00
IUUC-Vvi-131508	Vitis vinifera	32.50	1.00e-104	372.00
IUUC-Xma-133384	Xiphophorus maculatus	32.11	5.00e-84	303.00
IUUC-Yli-134588	Yarrowia lipolytica	32.31	3.00e-134	470.00
IUUC-Zma-135801	Zea mays	31.58	2.00e-95	342.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence