iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071484

Ensembl Protein ID

ENSONIP00000003866.1

UniProt Accession

I3J4S6; I3J4S6_ORENI

Genbank Protein ID

ENSONIP00000003866

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01004407

Gene Name

sh3rf1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000003088.1	ENSONIT00000003867.1	ENSONIP00000003866.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.50e-09	36.2	12	53
UBD/SH3	2.70e-46	155.8	434	489

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Clq +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCRRCLQGI----LGSRGELRCPECR 53
           **********9***************999....99**********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             ++++y++ ++deL+l+kG++ lv+ + +   gW kg++  +gk G+fP n++  ++
   Q: 434  YVAMFPYTPRKEDELELRKGEMFLVL-ERC-QDGWFKGTSMHTGKIGVFPGNYMSPVS 489
           6799**********************.555.569*******************99875 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MDESVLLDLL ECPVCLERLD ASAKVLPCQH TFCRRCLQGI LGSRGELRCP ECRTLVECAV 60
DELPSNILLV RLLDGIKQRP RRVGPGAAVC TNGTSGAMAR AHGSGSRDQG TPGAQPQRAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCTTGTTC CAGCAGCAGT CCCGCAGAGC AGAAGTACCA GCATGGCGCT CGGTGAGGCT 60
GGAGTTCCGT TGTCTCTCTT GTATTGTGTT TCTCATGTCA GGTTTTACTC CACTATCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF14604--SH3_9
PF13445--zf-RING_UBOX

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	68.24	0.00e+00	707.00
IUUC-Apl-003961	Anas platyrhynchos	65.15	0.00e+00	753.00
IUUC-Aca-004386	Anolis carolinensis	59.38	0.00e+00	858.00
IUUC-Ame-010659	Astyanax mexicanus	74.69	0.00e+00	1135.00
IUUC-Bta-012563	Bos taurus	76.69	2.00e-94	340.00
IUUC-Cja-019730	Callithrix jacchus	74.93	2.00e-147	516.00
IUUC-Cfa-020992	Canis familiaris	75.20	2.00e-151	530.00
IUUC-Cpo-021304	Cavia porcellus	75.75	7.00e-153	534.00
IUUC-Csa-023925	Chlorocebus sabaeus	75.48	6.00e-152	531.00
IUUC-Cho-024630	Choloepus hoffmanni	57.52	5.00e-109	389.00
IUUC-Cin-025274	Ciona intestinalis	48.22	2.00e-71	262.00
IUUC-Csv-026136	Ciona savignyi	42.86	1.00e-72	267.00
IUUC-Dre-028290	Danio rerio	81.13	0.00e+00	1009.00
IUUC-Dor-030388	Dipodomys ordii	76.32	2.00e-147	516.00
IUUC-Dme-032207	Drosophila melanogaster	44.85	3.00e-66	246.00
IUUC-Ete-032809	Echinops telfairi	53.25	9.00e-141	494.00
IUUC-Eca-034185	Equus caballus	78.99	2.00e-102	367.00
IUUC-Eeu-034816	Erinaceus europaeus	67.31	6.00e-128	452.00
IUUC-Fca-036439	Felis catus	61.61	0.00e+00	721.00
IUUC-Fal-037074	Ficedula albicollis	67.03	0.00e+00	726.00
IUUC-Gmo-039443	Gadus morhua	70.27	1.00e-144	507.00
IUUC-Gga-040749	Gallus gallus	66.72	0.00e+00	720.00
IUUC-Gac-041420	Gasterosteus aculeatus	80.92	0.00e+00	916.00
IUUC-Ggo-045215	Gorilla gorilla	75.20	2.00e-151	530.00
IUUC-Hsa-046315	Homo sapiens	74.93	3.00e-151	529.00
IUUC-Lch-049453	Latimeria chalumnae	63.95	3.00e-172	598.00
IUUC-Laf-053651	Loxodonta africana	64.35	0.00e+00	691.00
IUUC-Mcc-054688	Macaca mulatta	75.20	1.00e-151	530.00
IUUC-Meu-056291	Macropus eugenii	50.73	2.00e-87	317.00
IUUC-Mga-059944	Meleagris gallopavo	59.27	0.00e+00	878.00
IUUC-Mmr-061553	Microcebus murinus	75.48	3.00e-151	529.00
IUUC-Mdo-062313	Monodelphis domestica	59.97	0.00e+00	666.00
IUUC-Mmu-063516	Mus musculus	62.41	0.00e+00	717.00
IUUC-Mpu-066064	Mustela putorius furo	75.20	3.00e-150	526.00
IUUC-Mlu-067312	Myotis lucifugus	65.86	0.00e+00	685.00
IUUC-Nle-069035	Nomascus leucogenys	75.20	1.00e-151	530.00
IUUC-Opr-070739	Ochotona princeps	42.86	1.00e-97	350.00
IUUC-Oan-073305	Ornithorhynchus anatinus	67.68	0.00e+00	731.00
IUUC-Ocu-074936	Oryctolagus cuniculus	75.61	1.00e-150	527.00
IUUC-Ola-086675	Oryzias latipes	81.16	0.00e+00	932.00
IUUC-Oga-087933	Otolemur garnettii	64.92	1.00e-152	533.00
IUUC-Oar-090408	Ovis aries	60.48	5.00e-137	481.00
IUUC-Ptr-090865	Pan troglodytes	75.20	1.00e-151	530.00
IUUC-Pan-092362	Papio anubis	75.20	3.00e-151	529.00
IUUC-Psi-093876	Pelodiscus sinensis	61.40	0.00e+00	714.00
IUUC-Pfo-097116	Poecilia formosa	87.51	0.00e+00	1326.00
IUUC-Pab-098127	Pongo abelii	75.20	2.00e-151	530.00
IUUC-Pca-100485	Procavia capensis	67.00	0.00e+00	701.00
IUUC-Pva-102661	Pteropus vampyrus	74.93	6.00e-150	525.00
IUUC-Rno-105728	Rattus norvegicus	75.20	2.00e-146	513.00
IUUC-Sha-106515	Sarcophilus harrisii	67.28	0.00e+00	671.00
IUUC-Sar-113161	Sorex araneus	75.14	2.00e-142	499.00
IUUC-Ssc-115314	Sus scrofa	66.78	0.00e+00	691.00
IUUC-Tgu-117012	Taeniopygia guttata	64.26	0.00e+00	746.00
IUUC-Tru-118467	Takifugu rubripes	87.34	0.00e+00	877.00
IUUC-Tsy-119566	Tarsius syrichta	69.79	1.00e-130	460.00
IUUC-Tni-120830	Tetraodon nigroviridis	76.93	0.00e+00	902.00
IUUC-Tbe-128070	Tupaia belangeri	75.75	2.00e-151	529.00
IUUC-Ttr-128161	Tursiops truncatus	78.43	1.00e-111	397.00
IUUC-Vpa-130075	Vicugna pacos	67.21	2.00e-47	183.00
IUUC-Xtr-132628	Xenopus tropicalis	63.34	0.00e+00	715.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence