iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040175

Ensembl Protein ID

ENSGALP00000044324.2

UniProt Accession

A0A1D5NVF0; A0A1D5NVF0_CHICK

Genbank Protein ID

ENSGALP00000044324

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AADN04000021

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000010659.7	ENSGALT00000066079.2	ENSGALP00000044324.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-08	35.5	174	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 174  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 220
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

VRGVAAAGHP AQRVAAAGEA LKEIDDVYEK YKSENDPAQK KRLQQHLQRA LINSQELGDE 60
KIQIVTQMLE LVENRARQME THSQCFQDLS ENDKPLEKAK MESCQPERSS RRPRRQRTSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCGTGGAG TCGCTGCCGC TGGACATCCA GCGCAACGTG TCGCTGCTGC GGGAGGTGGA 60
CACCCGGTGC CAAGGTGGGC TCCGGCACTC GGCCTCCGCC GCGGGGCAGC GGGAGGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	77.91	3.00e-82	297.00
IUUC-Apl-003705	Anas platyrhynchos	99.10	8.00e-104	369.00
IUUC-Aca-004990	Anolis carolinensis	89.24	5.00e-92	330.00
IUUC-Bta-012721	Bos taurus	77.11	1.00e-81	295.00
IUUC-Cja-018960	Callithrix jacchus	88.42	3.00e-73	268.00
IUUC-Cfa-020869	Canis familiaris	77.51	1.00e-81	296.00
IUUC-Cpo-021414	Cavia porcellus	75.90	6.00e-80	290.00
IUUC-Csa-023304	Chlorocebus sabaeus	89.47	1.00e-74	272.00
IUUC-Dno-029945	Dasypus novemcinctus	77.91	2.00e-83	301.00
IUUC-Dor-030141	Dipodomys ordii	76.31	1.00e-78	285.00
IUUC-Ete-032709	Echinops telfairi	86.55	5.00e-89	320.00
IUUC-Eca-033432	Equus caballus	77.51	3.00e-81	295.00
IUUC-Eeu-035285	Erinaceus europaeus	90.64	2.00e-82	298.00
IUUC-Fca-036467	Felis catus	77.51	2.00e-81	295.00
IUUC-Fal-036700	Ficedula albicollis	98.21	7.00e-103	365.00
IUUC-Hsa-045837	Homo sapiens	89.47	1.00e-74	272.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	77.11	2.00e-81	295.00
IUUC-Lch-049965	Latimeria chalumnae	84.75	9.00e-87	312.00
IUUC-Laf-053353	Loxodonta africana	87.44	4.00e-89	320.00
IUUC-Mcc-055155	Macaca mulatta	88.51	9.00e-65	238.00
IUUC-Meu-056470	Macropus eugenii	89.24	3.00e-90	324.00
IUUC-Mga-059570	Meleagris gallopavo	99.55	5.00e-104	369.00
IUUC-Mmr-061385	Microcebus murinus	88.95	4.00e-74	271.00
IUUC-Mdo-062144	Monodelphis domestica	89.69	1.00e-90	325.00
IUUC-Mmu-063215	Mus musculus	77.11	3.00e-81	294.00
IUUC-Mpu-065749	Mustela putorius furo	89.66	1.00e-81	295.00
IUUC-Mlu-067245	Myotis lucifugus	68.97	2.00e-73	267.00
IUUC-Nle-069968	Nomascus leucogenys	89.47	7.00e-74	269.00
IUUC-Ocu-074870	Oryctolagus cuniculus	77.91	1.00e-82	298.00
IUUC-Oga-088336	Otolemur garnettii	89.47	1.00e-74	272.00
IUUC-Oar-090136	Ovis aries	77.51	4.00e-82	297.00
IUUC-Ptr-091348	Pan troglodytes	89.47	4.00e-74	270.00
IUUC-Pan-092819	Papio anubis	89.47	1.00e-74	272.00
IUUC-Psi-093854	Pelodiscus sinensis	92.53	2.00e-68	250.00
IUUC-Pab-098346	Pongo abelii	90.00	4.00e-75	274.00
IUUC-Pca-100278	Procavia capensis	80.08	1.00e-88	318.00
IUUC-Pva-103190	Pteropus vampyrus	77.51	8.00e-82	296.00
IUUC-Rno-104940	Rattus norvegicus	75.90	3.00e-80	291.00
IUUC-Sha-107533	Sarcophilus harrisii	89.24	4.00e-90	323.00
IUUC-Sar-113630	Sorex araneus	89.16	9.00e-81	292.00
IUUC-Ssc-115734	Sus scrofa	77.51	1.00e-81	296.00
IUUC-Tgu-117034	Taeniopygia guttata	99.10	1.00e-103	368.00
IUUC-Tsy-119494	Tarsius syrichta	88.95	1.00e-73	268.00
IUUC-Ttr-128442	Tursiops truncatus	89.16	5.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence