iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044846

UUCD1 version

UUC-GoG-00689

Ensembl Protein ID

ENSGGOP00000017324.1

UniProt Accession

G3RNF8; G3RNF8_GORGO

Protein Name

Uncharacterized protein

Gene Name

KLHL7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005779.2	ENSGGOT00000022073.1	ENSGGOP00000017324.1
ENSGGOG00000005779.2	ENSGGOT00000005811.2	ENSGGOP00000005663.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.50e-18	67.3	22	88
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.70e-14	52.0	122	152

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dvil v++++++ah++vLaa+S++F+ +f++++ esk + +ve+kd +p+  ++l++F Yt +++ n
   Q: 22   CDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESK-SFEVELKDAEPDIIEQLVEFAYTARISVN 88
           9*************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi  +A+++dcp+Lk  a+dfi++hF+
   Q: 122  SNCLGISVLAECLDCPELKATADDFIHQHFT 152
           8*****************************7 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MLGGTDCRTF LTSHINLKKT LCDVILMVQE RKIPAHRVVL AAASHFFNLM FTTNMLESKS 60
FEVELKDAEP DIIEQLVEFA YTARISVNSN NVQSLLDAAN QYQIEPVKKM CVDFLKEQVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCGCTCCC TGAGCGCTTC TAAGGGGGCC GCCCGGCCTT GTCTTTCGGC AGTGGCCGAG 60
CCACCGCTGC CTGCCGCGCG TTCCAGAGCT GGGCGTTGCA GCTGCACTGC CGATCGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030599--KLHL7
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001981	Ailuropoda melanoleuca	93.68	0.00e+00	1079.00
IUUC-Apl-003183	Anas platyrhynchos	93.97	0.00e+00	1073.00
IUUC-Aca-004273	Anolis carolinensis	93.59	0.00e+00	1071.00
IUUC-Ame-011343	Astyanax mexicanus	80.51	0.00e+00	900.00
IUUC-Bta-012785	Bos taurus	93.50	0.00e+00	1077.00
IUUC-Cja-019038	Callithrix jacchus	93.86	0.00e+00	1082.00
IUUC-Cfa-020774	Canis familiaris	95.05	0.00e+00	1076.00
IUUC-Cpo-021716	Cavia porcellus	93.50	0.00e+00	1072.00
IUUC-Csa-023029	Chlorocebus sabaeus	93.86	0.00e+00	1079.00
IUUC-Cho-024947	Choloepus hoffmanni	75.54	0.00e+00	768.00
IUUC-Dre-028014	Danio rerio	80.44	0.00e+00	813.00
IUUC-Dno-029946	Dasypus novemcinctus	93.68	0.00e+00	1078.00
IUUC-Dor-030916	Dipodomys ordii	80.83	6.00e-170	590.00
IUUC-Dse-031294	Dothistroma septosporum	32.58	5.00e-06	43.50
IUUC-Ete-032454	Echinops telfairi	86.12	1.00e-164	573.00
IUUC-Eca-034041	Equus caballus	93.32	0.00e+00	1077.00
IUUC-Eeu-034627	Erinaceus europaeus	96.77	0.00e+00	880.00
IUUC-Fca-035854	Felis catus	93.68	0.00e+00	1079.00
IUUC-Fal-036883	Ficedula albicollis	94.14	0.00e+00	1073.00
IUUC-Gmo-038902	Gadus morhua	76.52	0.00e+00	857.00
IUUC-Gga-040866	Gallus gallus	93.78	0.00e+00	1073.00
IUUC-Gac-041428	Gasterosteus aculeatus	75.69	0.00e+00	876.00
IUUC-Hsa-047034	Homo sapiens	93.86	0.00e+00	1079.00
IUUC-Itr-048807	Ictidomys tridecemlineatus	99.56	8.00e-132	462.00
IUUC-Lch-049815	Latimeria chalumnae	85.74	0.00e+00	968.00
IUUC-Loc-052232	Lepisosteus oculatus	80.50	0.00e+00	848.00
IUUC-Laf-053520	Loxodonta africana	94.70	0.00e+00	1078.00
IUUC-Mcc-055237	Macaca mulatta	93.86	0.00e+00	1079.00
IUUC-Meu-056095	Macropus eugenii	84.52	5.00e-156	543.00
IUUC-Mga-059927	Meleagris gallopavo	93.78	0.00e+00	1073.00
IUUC-Mvi-060550	Microbotryum violaceum	39.02	9.90e-01	29.30
IUUC-Mmr-060974	Microcebus murinus	93.68	0.00e+00	1077.00
IUUC-Mdo-062729	Monodelphis domestica	94.32	0.00e+00	1048.00
IUUC-Mmu-063841	Mus musculus	92.06	0.00e+00	1066.00
IUUC-Mpu-066524	Mustela putorius furo	94.88	0.00e+00	1078.00
IUUC-Mlu-067215	Myotis lucifugus	93.68	0.00e+00	1077.00
IUUC-Ncr-068856	Neurospora crassa	28.71	3.00e-04	39.30
IUUC-Nle-069341	Nomascus leucogenys	93.86	0.00e+00	1079.00
IUUC-Opr-070269	Ochotona princeps	93.50	0.00e+00	1078.00
IUUC-Ont-071551	Oreochromis niloticus	77.70	0.00e+00	874.00
IUUC-Oan-072718	Ornithorhynchus anatinus	94.33	0.00e+00	1072.00
IUUC-Ocu-074287	Oryctolagus cuniculus	93.86	0.00e+00	1079.00
IUUC-Ola-086718	Oryzias latipes	76.05	0.00e+00	884.00
IUUC-Oga-088757	Otolemur garnettii	93.50	0.00e+00	1078.00
IUUC-Oar-090309	Ovis aries	93.50	0.00e+00	1077.00
IUUC-Ptr-090509	Pan troglodytes	93.86	0.00e+00	1079.00
IUUC-Pan-092929	Papio anubis	93.86	0.00e+00	1079.00
IUUC-Psi-092941	Pelodiscus sinensis	94.33	0.00e+00	1077.00
IUUC-Pfo-097421	Poecilia formosa	77.16	0.00e+00	870.00
IUUC-Pab-097792	Pongo abelii	93.86	0.00e+00	1079.00
IUUC-Pca-101033	Procavia capensis	85.91	0.00e+00	763.00
IUUC-Pva-102364	Pteropus vampyrus	82.85	0.00e+00	934.00
IUUC-Rno-105596	Rattus norvegicus	92.24	0.00e+00	1069.00
IUUC-Sha-106815	Sarcophilus harrisii	94.42	0.00e+00	1057.00
IUUC-Sar-113305	Sorex araneus	94.52	0.00e+00	1079.00
IUUC-Ssc-115871	Sus scrofa	86.90	1.00e-148	518.00
IUUC-Tgu-116940	Taeniopygia guttata	93.77	0.00e+00	1069.00
IUUC-Tru-118682	Takifugu rubripes	76.42	0.00e+00	888.00
IUUC-Tsy-118787	Tarsius syrichta	92.37	0.00e+00	737.00
IUUC-Tni-120224	Tetraodon nigroviridis	77.35	0.00e+00	892.00
IUUC-Tbe-127633	Tupaia belangeri	57.05	8.00e-88	316.00
IUUC-Ttr-128500	Tursiops truncatus	94.69	0.00e+00	1077.00
IUUC-Vpa-130512	Vicugna pacos	93.22	0.00e+00	1055.00
IUUC-Xtr-131983	Xenopus tropicalis	92.50	0.00e+00	1060.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence