iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000029629.17	ENSMUST00000203459.2	ENSMUSP00000145355.1
ENSMUSG00000029629.17	ENSMUST00000115510.7	ENSMUSP00000111172.1
ENSMUSG00000029629.17	ENSMUST00000115511.8	ENSMUSP00000111173.2
ENSMUSG00000029629.17	ENSMUST00000133776.1	ENSMUSP00000115485.1
ENSMUSG00000029629.17	ENSMUST00000203045.1	ENSMUSP00000145527.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	Phospho.ELM
UniProt	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.30e-17	62.4	863	913

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
            C  C+ +g++e +lv+C++Cr ++H++Cl ++  ++ p+++   wiC++C+s
   Q: 863  ECSTCKGTGDNE-NLVRCDECRLCYHFGCLDPP-LKKSPKQTGygWICQECDS 913
           699******977.7*******************.77777776679******86 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MDRSSKRRQV KPLAASLLEA LDYDSSDDSD FKVGDASDSE GSGNGSEDPS KDSGEGSCSD 60
SEENILEEEL NEDIQVKEEQ LKNSTEEIMP SDKQLIKMEK KEEEENGERP RKKKEKEKEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTGGACGC GCTTGGGGGC GCGCGTGTGG GGCGCGCGCC GCGCCGCCCG GAGGGCCCCG 60
GAGGGAGCTG CCAGGCGCCT CTGCAGGCTC AGCGCCCAGA TCCCGCAGGA CAGGTCGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0048286--P:lung alveolus development
GO:0008285--P:negative regulation of cell proliferation
GO:0072201--P:negative regulation of mesenchymal cell proliferation
GO:2000791--P:negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000584--P:negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

KEGG

mmu:75725

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001978	Ailuropoda melanoleuca	97.42	0.00e+00	1447.00
IUUC-Apl-003491	Anas platyrhynchos	93.33	0.00e+00	1322.00
IUUC-Aca-004470	Anolis carolinensis	90.04	0.00e+00	1292.00
IUUC-Ame-011188	Astyanax mexicanus	81.87	0.00e+00	1049.00
IUUC-Bta-012312	Bos taurus	97.75	0.00e+00	1330.00
IUUC-Cel-018258	Caenorhabditis elegans	28.32	8.00e-48	185.00
IUUC-Cja-019931	Callithrix jacchus	97.79	0.00e+00	1445.00
IUUC-Cfa-021102	Canis familiaris	97.81	0.00e+00	1449.00
IUUC-Csa-023396	Chlorocebus sabaeus	96.94	0.00e+00	1446.00
IUUC-Cin-025300	Ciona intestinalis	34.65	6.00e-75	275.00
IUUC-Csv-026365	Ciona savignyi	59.65	4.00e-16	75.90
IUUC-Dre-028450	Danio rerio	82.02	0.00e+00	1041.00
IUUC-Dno-029245	Dasypus novemcinctus	94.08	0.00e+00	1360.00
IUUC-Dme-031650	Drosophila melanogaster	39.04	6.00e-119	422.00
IUUC-Ete-032829	Echinops telfairi	82.71	0.00e+00	1179.00
IUUC-Eca-033527	Equus caballus	97.29	0.00e+00	1449.00
IUUC-Eeu-035092	Erinaceus europaeus	84.47	0.00e+00	1038.00
IUUC-Fal-037349	Ficedula albicollis	92.72	0.00e+00	1323.00
IUUC-Gmo-038924	Gadus morhua	80.63	0.00e+00	1023.00
IUUC-Gga-040604	Gallus gallus	92.26	0.00e+00	1352.00
IUUC-Gac-041895	Gasterosteus aculeatus	79.41	0.00e+00	1018.00
IUUC-Ggo-044724	Gorilla gorilla	91.47	0.00e+00	1315.00
IUUC-Hsa-046740	Homo sapiens	98.06	0.00e+00	1450.00
IUUC-Lch-050481	Latimeria chalumnae	91.80	0.00e+00	1241.00
IUUC-Loc-052530	Lepisosteus oculatus	84.18	0.00e+00	1254.00
IUUC-Laf-053683	Loxodonta africana	97.74	0.00e+00	1384.00
IUUC-Mcc-055254	Macaca mulatta	96.69	0.00e+00	1443.00
IUUC-Meu-056124	Macropus eugenii	71.35	0.00e+00	944.00
IUUC-Mmr-061716	Microcebus murinus	97.94	0.00e+00	1459.00
IUUC-Mpu-065850	Mustela putorius furo	95.19	0.00e+00	1388.00
IUUC-Mlu-067977	Myotis lucifugus	97.60	0.00e+00	1329.00
IUUC-Nle-070024	Nomascus leucogenys	98.40	0.00e+00	1432.00
IUUC-Opr-070669	Ochotona princeps	83.02	0.00e+00	1100.00
IUUC-Ont-072407	Oreochromis niloticus	73.04	0.00e+00	1145.00
IUUC-Ola-087564	Oryzias latipes	82.29	0.00e+00	1115.00
IUUC-Oga-088503	Otolemur garnettii	98.03	0.00e+00	1325.00
IUUC-Oar-090254	Ovis aries	97.42	0.00e+00	1453.00
IUUC-Ptr-090811	Pan troglodytes	98.45	0.00e+00	1326.00
IUUC-Psi-093869	Pelodiscus sinensis	93.09	0.00e+00	1361.00
IUUC-Pma-094703	Petromyzon marinus	61.24	0.00e+00	758.00
IUUC-Pfo-097375	Poecilia formosa	83.63	0.00e+00	1018.00
IUUC-Pab-098645	Pongo abelii	98.06	0.00e+00	1451.00
IUUC-Pca-100931	Procavia capensis	87.36	0.00e+00	941.00
IUUC-Pva-102902	Pteropus vampyrus	92.65	0.00e+00	1414.00
IUUC-Rno-105725	Rattus norvegicus	98.28	0.00e+00	1374.00
IUUC-Sha-107008	Sarcophilus harrisii	92.97	0.00e+00	1361.00
IUUC-Sar-113710	Sorex araneus	88.94	0.00e+00	999.00
IUUC-Ssc-116271	Sus scrofa	97.90	0.00e+00	1335.00
IUUC-Tru-117706	Takifugu rubripes	81.69	0.00e+00	1080.00
IUUC-Tsy-118886	Tarsius syrichta	97.68	0.00e+00	1442.00
IUUC-Tni-120623	Tetraodon nigroviridis	75.31	0.00e+00	1023.00
IUUC-Tbe-127618	Tupaia belangeri	85.76	5.00e-134	472.00
IUUC-Ttr-129058	Tursiops truncatus	92.65	0.00e+00	1351.00
IUUC-Vpa-130327	Vicugna pacos	95.61	0.00e+00	1445.00
IUUC-Xtr-132030	Xenopus tropicalis	78.18	0.00e+00	1241.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence