iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009940.1	ENSSHAT00000011662.1	ENSSHAP00000011566.1
ENSSHAG00000009940.1	ENSSHAT00000011663.1	ENSSHAP00000011567.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.30e-17	62.6	822	872

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
            C  C+ +g++e +lv+C+ Cr ++H +Cl ++  ++ p+++   wiC++C+s
   Q: 822  ECSTCKGTGDNE-NLVRCDGCRLCYHLGCLDPP-LKKSPKQTGygWICQECDS 872
           699******977.7*******************.77777776679******86 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MCLPFCRVFP HFGGFICVRV VCVCVCIYIC VVFFFLIFST DSEGSGNGSE DPSKDSGEGS 60
CSDSEENVLE EELAEETKVE AETLKSAAGE DTLGAEKAPG KVEKKEEEGE DKPRKRKEKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGCAAGTT GTGACCAGGT TGGGGGTGTG GGCCATTTTT TTTTTTTTTT TTTAACTTAA 60
AAATGTGTCT ACCATTCTGC CGGGTGTTCC CCCATTTTGG CGGCTTCATT TGTGTCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0048286--P:lung alveolus development
GO:2000791--P:negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000584--P:negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001978	Ailuropoda melanoleuca	93.29	0.00e+00	1394.00
IUUC-Apl-003491	Anas platyrhynchos	92.40	0.00e+00	1305.00
IUUC-Aca-004470	Anolis carolinensis	89.77	0.00e+00	1283.00
IUUC-Ame-011188	Astyanax mexicanus	82.18	0.00e+00	1045.00
IUUC-Bta-012312	Bos taurus	93.75	0.00e+00	1293.00
IUUC-Cel-018258	Caenorhabditis elegans	28.54	7.00e-47	181.00
IUUC-Cja-019931	Callithrix jacchus	93.63	0.00e+00	1390.00
IUUC-Cfa-021102	Canis familiaris	93.42	0.00e+00	1393.00
IUUC-Csa-023396	Chlorocebus sabaeus	92.73	0.00e+00	1391.00
IUUC-Cin-025300	Ciona intestinalis	35.05	3.00e-75	275.00
IUUC-Csv-026365	Ciona savignyi	59.65	4.00e-16	75.50
IUUC-Dre-028450	Danio rerio	81.80	0.00e+00	1034.00
IUUC-Dno-029245	Dasypus novemcinctus	94.51	0.00e+00	1290.00
IUUC-Dme-031650	Drosophila melanogaster	37.44	3.00e-107	383.00
IUUC-Ete-032829	Echinops telfairi	79.15	0.00e+00	1133.00
IUUC-Eca-033527	Equus caballus	93.03	0.00e+00	1395.00
IUUC-Eeu-035092	Erinaceus europaeus	82.64	0.00e+00	1012.00
IUUC-Fal-037349	Ficedula albicollis	91.15	0.00e+00	1313.00
IUUC-Gmo-038924	Gadus morhua	80.63	0.00e+00	1015.00
IUUC-Gga-040604	Gallus gallus	91.10	0.00e+00	1328.00
IUUC-Gac-041895	Gasterosteus aculeatus	79.26	0.00e+00	1008.00
IUUC-Ggo-044724	Gorilla gorilla	87.34	0.00e+00	1260.00
IUUC-Hsa-046740	Homo sapiens	93.80	0.00e+00	1397.00
IUUC-Lch-050481	Latimeria chalumnae	91.95	0.00e+00	1231.00
IUUC-Loc-052530	Lepisosteus oculatus	84.64	0.00e+00	1241.00
IUUC-Laf-053683	Loxodonta africana	94.15	0.00e+00	1345.00
IUUC-Mcc-055254	Macaca mulatta	92.61	0.00e+00	1391.00
IUUC-Meu-056124	Macropus eugenii	75.74	0.00e+00	989.00
IUUC-Mmr-061716	Microcebus murinus	93.94	0.00e+00	1404.00
IUUC-Mmu-064063	Mus musculus	93.29	0.00e+00	1362.00
IUUC-Mpu-065850	Mustela putorius furo	91.82	0.00e+00	1345.00
IUUC-Mlu-067977	Myotis lucifugus	94.18	0.00e+00	1285.00
IUUC-Nle-070024	Nomascus leucogenys	94.67	0.00e+00	1383.00
IUUC-Opr-070669	Ochotona princeps	81.64	0.00e+00	1078.00
IUUC-Ont-072407	Oreochromis niloticus	73.26	0.00e+00	1135.00
IUUC-Ola-087564	Oryzias latipes	82.14	0.00e+00	1106.00
IUUC-Oga-088503	Otolemur garnettii	95.08	0.00e+00	1290.00
IUUC-Oar-090254	Ovis aries	92.58	0.00e+00	1399.00
IUUC-Ptr-090811	Pan troglodytes	94.94	0.00e+00	1288.00
IUUC-Psi-093869	Pelodiscus sinensis	91.73	0.00e+00	1344.00
IUUC-Pma-094703	Petromyzon marinus	61.40	0.00e+00	752.00
IUUC-Pfo-097375	Poecilia formosa	83.80	0.00e+00	1015.00
IUUC-Pab-098645	Pongo abelii	93.80	0.00e+00	1396.00
IUUC-Pca-100931	Procavia capensis	85.53	0.00e+00	916.00
IUUC-Pva-102902	Pteropus vampyrus	94.78	0.00e+00	1337.00
IUUC-Rno-105725	Rattus norvegicus	93.14	0.00e+00	1326.00
IUUC-Sar-113710	Sorex araneus	85.59	0.00e+00	966.00
IUUC-Ssc-116271	Sus scrofa	94.41	0.00e+00	1297.00
IUUC-Tru-117706	Takifugu rubripes	81.54	0.00e+00	1071.00
IUUC-Tsy-118886	Tarsius syrichta	93.03	0.00e+00	1386.00
IUUC-Tni-120623	Tetraodon nigroviridis	75.77	0.00e+00	1020.00
IUUC-Tbe-127618	Tupaia belangeri	80.90	4.00e-126	445.00
IUUC-Ttr-129058	Tursiops truncatus	88.77	0.00e+00	1304.00
IUUC-Vpa-130327	Vicugna pacos	93.64	0.00e+00	1404.00
IUUC-Xtr-132030	Xenopus tropicalis	77.60	0.00e+00	1229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence