iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059819

UUCD1 version

UUC-MeG-00037

Ensembl Protein ID

ENSMGAP00000000271.2

UniProt Accession

G1MQC4; G1MQC4_MELGA

Protein Name

Uncharacterized protein

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000000859.2	ENSMGAT00000000906.2	ENSMGAP00000000271.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	75.25	0.00e+00	786.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

NSTPPGSLDL NQPGFAKEIL GTKLEVKYLC SDCRNILRRP FQAQCGHRYC SYCLKKIISS 60
GPQKCASCIQ EGIYEEGVSI LETSSAFPDN AARREVESLP AVCINEGCTW KGTIKEYESC 120

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Nucleotide Sequence
(Fasta)

AATTCGACTC CGCCCGGCTC TCTGGACCTG AACCAGCCCG GGTTTGCGAA GGAGATCCTG 60
GGAACTAAGC TGGAGGTGAA GTACCTCTGC TCGGACTGCA GGAACATACT GAGGCGGCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	71.48	0.00e+00	756.00
IUUC-Atr-002634	Amborella trichopoda	27.61	5.00e-06	47.40
IUUC-Apl-004202	Anas platyrhynchos	84.56	0.00e+00	915.00
IUUC-Aca-005029	Anolis carolinensis	57.34	2.00e-142	498.00
IUUC-Ame-011841	Astyanax mexicanus	52.27	4.00e-161	560.00
IUUC-Bta-013180	Bos taurus	71.29	0.00e+00	749.00
IUUC-Cja-019813	Callithrix jacchus	74.85	0.00e+00	784.00
IUUC-Cfa-021205	Canis familiaris	75.05	0.00e+00	764.00
IUUC-Cpo-021346	Cavia porcellus	74.85	0.00e+00	773.00
IUUC-Csa-023809	Chlorocebus sabaeus	74.72	0.00e+00	687.00
IUUC-Dre-027669	Danio rerio	57.91	4.00e-174	603.00
IUUC-Dno-029458	Dasypus novemcinctus	72.07	0.00e+00	765.00
IUUC-Dor-030338	Dipodomys ordii	73.44	0.00e+00	710.00
IUUC-Eca-034401	Equus caballus	74.05	0.00e+00	782.00
IUUC-Eeu-034668	Erinaceus europaeus	83.55	8.00e-77	280.00
IUUC-Fca-036057	Felis catus	72.06	0.00e+00	779.00
IUUC-Fal-037560	Ficedula albicollis	77.80	0.00e+00	766.00
IUUC-Gmo-038964	Gadus morhua	62.32	0.00e+00	642.00
IUUC-Gga-040425	Gallus gallus	90.48	0.00e+00	956.00
IUUC-Gac-041908	Gasterosteus aculeatus	63.60	0.00e+00	661.00
IUUC-Ggo-044606	Gorilla gorilla	67.81	0.00e+00	696.00
IUUC-Hsa-046952	Homo sapiens	75.25	0.00e+00	786.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	64.62	0.00e+00	643.00
IUUC-Lch-049571	Latimeria chalumnae	60.83	0.00e+00	700.00
IUUC-Loc-051973	Lepisosteus oculatus	61.40	7.00e-177	613.00
IUUC-Laf-053815	Loxodonta africana	71.29	0.00e+00	730.00
IUUC-Mcc-054888	Macaca mulatta	75.05	0.00e+00	781.00
IUUC-Meu-056547	Macropus eugenii	82.91	2.00e-133	468.00
IUUC-Mdo-062570	Monodelphis domestica	78.40	0.00e+00	816.00
IUUC-Mmu-063133	Mus musculus	72.84	0.00e+00	742.00
IUUC-Mpu-065802	Mustela putorius furo	72.37	0.00e+00	773.00
IUUC-Nle-070155	Nomascus leucogenys	75.45	0.00e+00	793.00
IUUC-Opr-070856	Ochotona princeps	70.18	6.00e-93	334.00
IUUC-Ont-071930	Oreochromis niloticus	64.81	0.00e+00	691.00
IUUC-Ola-087397	Oryzias latipes	60.79	0.00e+00	672.00
IUUC-Oga-088109	Otolemur garnettii	75.25	0.00e+00	790.00
IUUC-Oar-090310	Ovis aries	62.14	0.00e+00	651.00
IUUC-Ptr-090643	Pan troglodytes	75.45	0.00e+00	791.00
IUUC-Pan-091933	Papio anubis	75.25	0.00e+00	783.00
IUUC-Psi-093681	Pelodiscus sinensis	79.53	0.00e+00	827.00
IUUC-Pfo-096148	Poecilia formosa	61.16	0.00e+00	680.00
IUUC-Pab-098631	Pongo abelii	75.25	0.00e+00	791.00
IUUC-Pca-100582	Procavia capensis	59.92	7.00e-78	284.00
IUUC-Pva-102396	Pteropus vampyrus	63.58	0.00e+00	629.00
IUUC-Rno-106120	Rattus norvegicus	70.62	0.00e+00	728.00
IUUC-Sha-106493	Sarcophilus harrisii	79.80	0.00e+00	831.00
IUUC-Sar-113570	Sorex araneus	86.19	2.00e-96	345.00
IUUC-Ssc-115843	Sus scrofa	70.35	0.00e+00	762.00
IUUC-Tgu-117144	Taeniopygia guttata	79.64	0.00e+00	786.00
IUUC-Tru-117853	Takifugu rubripes	61.71	0.00e+00	677.00
IUUC-Tni-120256	Tetraodon nigroviridis	65.59	0.00e+00	700.00
IUUC-Tbe-127943	Tupaia belangeri	59.60	3.00e-90	324.00
IUUC-Ttr-129246	Tursiops truncatus	72.71	0.00e+00	754.00
IUUC-Vvi-131592	Vitis vinifera	27.21	2.00e-05	45.10
IUUC-Xtr-132279	Xenopus tropicalis	61.92	5.00e-175	607.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence