iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044817

UUCD1 version

UUC-GoG-00133

Ensembl Protein ID

ENSGGOP00000003104.2

UniProt Accession

G3QKW9; G3QKW9_GORGO

Protein Name

Uncharacterized protein

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000003159.2	ENSGGOT00000003174.2	ENSGGOP00000003104.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.30e-17	63.5	35	101
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.10e-10	39.7	133	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e +e k k++v+++ v+p  +  ++k+lY+ ++d+n+
   Q: 35   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEAK-KKEVVLDNVDPAILDLIIKYLYSASIDLND 101
           9***********************************9.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 133  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 163
           56***************************99 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

RMDSQRELAE ELRLYQSTLL QDGLKDLLDE KKFIDCTLKA GDKSLPCHRL ILSACSPYFR 60
EYFLSEIDEA KKKEVVLDNV DPAILDLIIK YLYSASIDLN DGNVQDIFAL ASRFQIPSVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTTACAG CTAGACCTGT GTGCTGCAAG GAGCTAAGGC CTTCAGTGTC CCCTTCCTTA 60
CCCAGGTTTC TCACAGAATG GATTCCCAGC GGGAACTTGC AGAGGAACTG CGGCTTTACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	96.87	0.00e+00	1182.00
IUUC-Apl-003866	Anas platyrhynchos	86.00	0.00e+00	1041.00
IUUC-Ame-011172	Astyanax mexicanus	61.86	0.00e+00	753.00
IUUC-Bta-012925	Bos taurus	97.52	0.00e+00	1188.00
IUUC-Bci-013875	Botrytis cinerea	29.58	1.00e-18	87.00
IUUC-Bdi-014115	Brachypodium distachyon	24.05	5.00e-11	62.00
IUUC-Cja-019348	Callithrix jacchus	98.35	0.00e+00	1194.00
IUUC-Cfa-020782	Canis familiaris	97.69	0.00e+00	1189.00
IUUC-Cpo-021825	Cavia porcellus	93.23	0.00e+00	1136.00
IUUC-Csa-023184	Chlorocebus sabaeus	99.04	0.00e+00	1026.00
IUUC-Cin-025237	Ciona intestinalis	29.45	1.00e-70	260.00
IUUC-Dre-028278	Danio rerio	60.43	0.00e+00	775.00
IUUC-Dno-029516	Dasypus novemcinctus	95.54	0.00e+00	1168.00
IUUC-Dor-030850	Dipodomys ordii	92.96	0.00e+00	759.00
IUUC-Ete-032697	Echinops telfairi	94.39	0.00e+00	1134.00
IUUC-Eca-033714	Equus caballus	97.20	0.00e+00	1189.00
IUUC-Eeu-035245	Erinaceus europaeus	94.90	0.00e+00	1070.00
IUUC-Gmo-039392	Gadus morhua	57.47	0.00e+00	732.00
IUUC-Ggr-040041	Gaeumannomyces graminis	27.78	5.00e-08	52.00
IUUC-Gga-041106	Gallus gallus	85.48	0.00e+00	1055.00
IUUC-Gac-042252	Gasterosteus aculeatus	60.53	0.00e+00	772.00
IUUC-Hsa-046620	Homo sapiens	99.83	0.00e+00	1205.00
IUUC-Lch-050477	Latimeria chalumnae	69.80	0.00e+00	859.00
IUUC-Loc-051955	Lepisosteus oculatus	70.51	0.00e+00	914.00
IUUC-Laf-053500	Loxodonta africana	96.53	0.00e+00	1174.00
IUUC-Mcc-055316	Macaca mulatta	99.34	0.00e+00	1200.00
IUUC-Mor-057181	Magnaporthe oryzae	26.35	1.00e-10	60.50
IUUC-Mmr-061444	Microcebus murinus	98.35	0.00e+00	1191.00
IUUC-Mmu-064147	Mus musculus	95.38	0.00e+00	1164.00
IUUC-Mlu-067481	Myotis lucifugus	94.72	0.00e+00	1162.00
IUUC-Ncr-068938	Neurospora crassa	32.88	9.00e-08	52.00
IUUC-Nle-069339	Nomascus leucogenys	99.67	0.00e+00	1203.00
IUUC-Opr-070703	Ochotona princeps	96.37	0.00e+00	1130.00
IUUC-Ont-072420	Oreochromis niloticus	59.97	0.00e+00	793.00
IUUC-Oan-073476	Ornithorhynchus anatinus	92.74	0.00e+00	1137.00
IUUC-Ocu-074248	Oryctolagus cuniculus	96.71	0.00e+00	1186.00
IUUC-Ola-086361	Oryzias latipes	61.50	0.00e+00	780.00
IUUC-Oar-090349	Ovis aries	97.19	0.00e+00	1187.00
IUUC-Pan-092069	Papio anubis	99.50	0.00e+00	1201.00
IUUC-Psi-093671	Pelodiscus sinensis	88.45	0.00e+00	1053.00
IUUC-Pfo-096122	Poecilia formosa	61.79	0.00e+00	809.00
IUUC-Pab-098711	Pongo abelii	99.67	0.00e+00	1205.00
IUUC-Pca-100495	Procavia capensis	88.45	0.00e+00	1055.00
IUUC-Pva-102401	Pteropus vampyrus	97.03	0.00e+00	1184.00
IUUC-Rno-105969	Rattus norvegicus	95.21	0.00e+00	1161.00
IUUC-Sar-113405	Sorex araneus	93.07	0.00e+00	1125.00
IUUC-Tgu-116725	Taeniopygia guttata	85.81	0.00e+00	1075.00
IUUC-Tru-117743	Takifugu rubripes	58.88	0.00e+00	762.00
IUUC-Tsy-119225	Tarsius syrichta	90.43	0.00e+00	1082.00
IUUC-Tni-120547	Tetraodon nigroviridis	61.96	0.00e+00	791.00
IUUC-Ttr-128645	Tursiops truncatus	97.03	0.00e+00	1182.00
IUUC-Vpa-130714	Vicugna pacos	97.36	0.00e+00	1186.00
IUUC-Xtr-132144	Xenopus tropicalis	76.28	0.00e+00	946.00
IUUC-Xma-133860	Xiphophorus maculatus	61.96	0.00e+00	810.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence