iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000012867.3	ENSCJAT00000024929.3	ENSCJAP00000023565.3
ENSCJAG00000012867.3	ENSCJAT00000024931.1	ENSCJAP00000023567.1
ENSCJAG00000012867.3	ENSCJAT00000062072.1	ENSCJAP00000047842.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.30e-37	127.9	15	157

Active Site

Position(s)	Description	Evidence
97	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFk.leiefpedYPfkPP...kvkfltkifhPnvyenGkvClsilk. 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk   ++ p ++P  PP    +++ ++++hPn+ye+G+vC+sil+ 
   Q: 15   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKeGAVRPPVSFPGPPPpccAFRCRSQMWHPNIYETGDVCISILHp 103
           599*****************************************84689999*****9993333567788*****************99 PP
   S: 88   ..........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                     ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 104  pvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 157
           9999999*9******************************************998 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKE 60
GAVRPPVSFP GPPPPCCAFR CRSQMWHPNI YETGDVCISI LHPPVDDPQS GELPSERWNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCGGC CGCTGGTTCC CAGCTCGCAG AAGGCGCTGC TGCTGGAGCT GAAGGGGCTC 60
CAGGAGGAGC CGGTCGAGGG CTTCCGCGTG ACCCTGGTGG ACGAGGGCGA CCTGTACAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	89.91	2.00e-116	410.00
IUUC-Bta-012516	Bos taurus	89.52	9.00e-106	375.00
IUUC-Cfa-020203	Canis familiaris	90.35	1.00e-106	378.00
IUUC-Cpo-022139	Cavia porcellus	84.07	6.00e-106	376.00
IUUC-Csa-023371	Chlorocebus sabaeus	89.47	5.00e-108	383.00
IUUC-Dor-030875	Dipodomys ordii	89.96	1.00e-108	385.00
IUUC-Fca-035832	Felis catus	96.03	6.00e-84	302.00
IUUC-Gga-040694	Gallus gallus	89.17	2.00e-108	384.00
IUUC-Ggo-044806	Gorilla gorilla	89.91	3.00e-108	384.00
IUUC-Hsa-046245	Homo sapiens	89.91	5.00e-108	383.00
IUUC-Mcc-054665	Macaca mulatta	85.96	5.00e-101	359.00
IUUC-Mga-060075	Meleagris gallopavo	88.75	5.00e-108	383.00
IUUC-Mmr-061165	Microcebus murinus	86.40	8.00e-107	379.00
IUUC-Mdo-061825	Monodelphis domestica	88.60	1.00e-105	375.00
IUUC-Mmu-064168	Mus musculus	90.00	5.00e-106	376.00
IUUC-Mpu-066009	Mustela putorius furo	89.91	4.00e-116	410.00
IUUC-Opr-070826	Ochotona princeps	84.93	9.00e-95	339.00
IUUC-Oan-073287	Ornithorhynchus anatinus	82.50	2.00e-103	367.00
IUUC-Ocu-074902	Oryctolagus cuniculus	86.67	1.00e-102	365.00
IUUC-Oga-088845	Otolemur garnettii	88.16	2.00e-111	394.00
IUUC-Ptr-090916	Pan troglodytes	89.05	5.00e-103	366.00
IUUC-Pan-092577	Papio anubis	89.47	5.00e-108	383.00
IUUC-Psi-093039	Pelodiscus sinensis	92.02	6.00e-77	279.00
IUUC-Pva-102875	Pteropus vampyrus	96.69	2.00e-74	271.00
IUUC-Rno-106079	Rattus norvegicus	90.00	5.00e-106	376.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence