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Tag Content
iUUCD ID IUUC-Acl-008168
Ensembl Protein ID CADACLAP00005561
UniProt Accession A1C4A5; MYO1_ASPCL
Genbank Protein ID EAW15245.1
Protein Name Myosin-1; Class I unconventional myosin; Type I myosin
Genbank Nucleotide ID DS026990
Gene Name ACLA_059080; myoA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADACLAG00005686 CADACLAT00005686 CADACLAP00005561
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 3.70e-11 41.7 1121 1175
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + ++lyd+++q+ +eL++k+G++v+++   ++ +gW+ + + ++  +G  Pe + e+
   Q: 1121 TAKALYDFNSQQPNELSIKAGEIVQIV--SKEGNGWWLCMNMATSSQGWTPEAYLEE 1175
           679************************..67788******************99875 PP
   
Organism Aspergillus clavatus
Functional Description
(View)

Functional Description


     Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
 Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
Protein Sequence
(Fasta)
MCAQCGAEPI SGINWARRER GYPVAWAPYP GKSVTAIMGH SRRPVGGEKK SRGFGRSKAA 60
ADVGDGRQAG KPQVKKAVFE STKKKEIGVS DLTLLSKISN EAINDNLKLR FEHDEIYTYI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Acl-008168|UBD,SH3|Aspergillus clavatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTGTGCGC AGTGTGGCGC AGAGCCCATC AGCGGGATCA ACTGGGCCAG GAGAGAGAGA 60
GGGTGCGTGT GTGTGTGAGA GAGAGAGTCC AGAGTCCTCC ACAGACAAAC CATCGTCATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Acl-008168|UBD,SH3|Aspergillus clavatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0378--Hydrolase
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
Interpro

IPR001609--Myosin_head_motor_dom
IPR010926--Myosin_TH1
IPR027417--P-loop_NTPase
IPR001452--SH3_domain
PROSITE

PS51456--MYOSIN_MOTOR
PS50002--SH3
PS51757--TH1
Pfam

PF00063--Myosin_head
PF06017--Myosin_TH1
PF00018--SH3_1
PRINTS

PR00193--MYOSINHEAVY
SMART

SM00242--MYSc
SM00326--SH3
Gene Ontology

GO:0030479--C:actin cortical patch
GO:0016459--C:myosin complex
GO:0005524--F:ATP binding
GO:0003774--F:motor activity
KEGG act:ACLA_059080
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002158 Ailuropoda melanoleuca 43.39 0.00e+00 753.00
IUUC-Apl-003803 Anas platyrhynchos 43.72 0.00e+00 754.00
IUUC-Aca-004926 Anolis carolinensis 39.63 0.00e+00 715.00
IUUC-Afl-008552 Aspergillus flavus 86.38 0.00e+00 2048.00
IUUC-Afu-008958 Aspergillus fumigatus 93.30 0.00e+00 2093.00
IUUC-Ang-009818 Aspergillus niger 92.40 0.00e+00 1906.00
IUUC-Aor-009891 Aspergillus oryzae 86.22 0.00e+00 2043.00
IUUC-Ate-010325 Aspergillus terreus 90.47 0.00e+00 1862.00
IUUC-Ame-011036 Astyanax mexicanus 39.96 0.00e+00 773.00
IUUC-Bta-012409 Bos taurus 43.67 0.00e+00 764.00
IUUC-Cel-018582 Caenorhabditis elegans 41.10 0.00e+00 695.00
IUUC-Cfa-020409 Canis familiaris 43.29 0.00e+00 758.00
IUUC-Cpo-021332 Cavia porcellus 43.63 0.00e+00 771.00
IUUC-Csa-023357 Chlorocebus sabaeus 44.09 0.00e+00 730.00
IUUC-Dre-027800 Danio rerio 39.95 0.00e+00 767.00
IUUC-Dno-029858 Dasypus novemcinctus 44.09 0.00e+00 731.00
IUUC-Dor-030253 Dipodomys ordii 40.56 2.00e-169 588.00
IUUC-Dse-031169 Dothistroma septosporum 43.14 3.00e-08 53.50
IUUC-Eca-034303 Equus caballus 43.23 0.00e+00 696.00
IUUC-Eeu-034561 Erinaceus europaeus 38.57 4.00e-50 191.00
IUUC-Fca-036174 Felis catus 40.91 0.00e+00 673.00
IUUC-Fal-037393 Ficedula albicollis 44.69 0.00e+00 754.00
IUUC-Gmo-038566 Gadus morhua 41.47 0.00e+00 668.00
IUUC-Gga-040323 Gallus gallus 44.64 0.00e+00 767.00
IUUC-Gac-042415 Gasterosteus aculeatus 44.14 0.00e+00 717.00
IUUC-Ggo-044547 Gorilla gorilla 39.84 0.00e+00 738.00
IUUC-Hsa-045712 Homo sapiens 43.62 0.00e+00 769.00
IUUC-Itr-048108 Ictidomys tridecemlineatus 42.90 0.00e+00 737.00
IUUC-Lch-050042 Latimeria chalumnae 42.66 0.00e+00 709.00
IUUC-Loc-052303 Lepisosteus oculatus 43.92 0.00e+00 761.00
IUUC-Lma-053101 Leptosphaeria maculans 29.41 9.00e-05 40.80
IUUC-Laf-054148 Loxodonta africana 42.69 0.00e+00 728.00
IUUC-Mcc-054773 Macaca mulatta 43.38 0.00e+00 768.00
IUUC-Meu-056504 Macropus eugenii 39.82 2.00e-83 302.00
IUUC-Mmr-061357 Microcebus murinus 44.97 0.00e+00 765.00
IUUC-Mdo-062467 Monodelphis domestica 43.34 0.00e+00 756.00
IUUC-Mmu-063711 Mus musculus 43.72 0.00e+00 765.00
IUUC-Mpu-066658 Mustela putorius furo 43.93 0.00e+00 767.00
IUUC-Mlu-067569 Myotis lucifugus 40.00 2.00e-07 49.70
IUUC-Nfi-068411 Neosartorya fischeri 95.39 0.00e+00 1924.00
IUUC-Nle-070144 Nomascus leucogenys 39.93 0.00e+00 738.00
IUUC-Ont-072236 Oreochromis niloticus 43.51 0.00e+00 760.00
IUUC-Oan-073284 Ornithorhynchus anatinus 29.50 8.00e-24 102.00
IUUC-Ola-087396 Oryzias latipes 44.15 0.00e+00 757.00
IUUC-Oga-088985 Otolemur garnettii 44.64 0.00e+00 763.00
IUUC-Oar-089527 Ovis aries 42.98 0.00e+00 709.00
IUUC-Ptr-090485 Pan troglodytes 43.99 0.00e+00 733.00
IUUC-Pan-092029 Papio anubis 43.38 0.00e+00 767.00
IUUC-Psi-094016 Pelodiscus sinensis 33.62 2.00e-136 478.00
IUUC-Pma-094458 Petromyzon marinus 43.93 0.00e+00 752.00
IUUC-Pfo-096486 Poecilia formosa 44.59 0.00e+00 728.00
IUUC-Pab-098517 Pongo abelii 39.42 0.00e+00 721.00
IUUC-Pca-100128 Procavia capensis 33.77 3.00e-68 251.00
IUUC-Pva-102994 Pteropus vampyrus 42.56 0.00e+00 686.00
IUUC-Pte-104380 Pyrenophora teres 31.37 5.00e-05 42.00
IUUC-Pyt-104764 Pyrenophora triticirepentis 31.37 5.00e-05 41.60
IUUC-Rno-105992 Rattus norvegicus 43.93 0.00e+00 768.00
IUUC-Sha-107424 Sarcophilus harrisii 42.47 0.00e+00 748.00
IUUC-Ssc-115400 Sus scrofa 44.07 0.00e+00 770.00
IUUC-Tgu-116572 Taeniopygia guttata 39.68 0.00e+00 694.00
IUUC-Tru-118665 Takifugu rubripes 43.09 0.00e+00 752.00
IUUC-Tni-120087 Tetraodon nigroviridis 39.82 0.00e+00 736.00
IUUC-Tre-122048 Trichoderma reesei 63.40 0.00e+00 1478.00
IUUC-Tbe-127462 Tupaia belangeri 35.44 1.00e-104 373.00
IUUC-Ttr-128783 Tursiops truncatus 44.31 0.00e+00 721.00
IUUC-Vda-130020 Verticillium dahliae 67.53 0.00e+00 1457.00
IUUC-Xtr-131936 Xenopus tropicalis 43.98 0.00e+00 727.00
Created Date 25-Jun-2017

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