iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034255

UUCD1 version

UUC-EqC-00439

Ensembl Protein ID

ENSECAP00000019563.1

UniProt Accession

F6X9G4; F6X9G4_HORSE

Protein Name

Uncharacterized protein

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021840.1	ENSECAT00000023609.1	ENSECAP00000019563.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-14	54.5	571	636

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 571  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 636
           79*********9977765156789*********************************..*******85 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

DFNYEYVQRE ALRVPLIFRE KDGLGIKMPD PDFTVRDVKL LVGNRRLVDV MDVNTQKGTE 60
MSMSQFVRYY ETPEAQRDKL YNVISLEFSH TKLEHLVKRP TVVDLVDWVD NMWPQHLKEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGATTTCA ACTATGAGTA CGTGCAGAGA GAAGCTCTCA GGGTTCCTCT GATATTTCGA 60
GAAAAGGATG GACTAGGAAT TAAGTAAGTT GCTGAAACTA ATCGCTTCTT TCCCTGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	97.93	0.00e+00	2200.00
IUUC-Apl-003787	Anas platyrhynchos	83.69	0.00e+00	1915.00
IUUC-Aca-004247	Anolis carolinensis	78.67	0.00e+00	1743.00
IUUC-Bta-013531	Bos taurus	97.52	0.00e+00	2246.00
IUUC-Cel-018303	Caenorhabditis elegans	46.44	2.00e-79	290.00
IUUC-Cja-018876	Callithrix jacchus	93.87	0.00e+00	2115.00
IUUC-Cfa-020857	Canis familiaris	97.60	0.00e+00	2247.00
IUUC-Cpo-021967	Cavia porcellus	93.91	0.00e+00	2040.00
IUUC-Csa-023210	Chlorocebus sabaeus	97.16	0.00e+00	2151.00
IUUC-Dre-028272	Danio rerio	64.44	0.00e+00	1446.00
IUUC-Dno-030034	Dasypus novemcinctus	94.96	0.00e+00	2117.00
IUUC-Dor-030736	Dipodomys ordii	86.97	0.00e+00	1003.00
IUUC-Eeu-035038	Erinaceus europaeus	99.12	0.00e+00	1200.00
IUUC-Fca-035786	Felis catus	98.24	0.00e+00	2301.00
IUUC-Fal-037589	Ficedula albicollis	83.65	0.00e+00	1952.00
IUUC-Gga-041103	Gallus gallus	86.18	0.00e+00	1047.00
IUUC-Gac-041304	Gasterosteus aculeatus	58.46	0.00e+00	956.00
IUUC-Ggo-044522	Gorilla gorilla	96.78	0.00e+00	1715.00
IUUC-Hsa-045877	Homo sapiens	97.19	0.00e+00	2173.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	97.35	0.00e+00	1325.00
IUUC-Lch-049950	Latimeria chalumnae	78.34	0.00e+00	1822.00
IUUC-Loc-051972	Lepisosteus oculatus	77.84	0.00e+00	1013.00
IUUC-Laf-053623	Loxodonta africana	97.27	0.00e+00	2107.00
IUUC-Mcc-054943	Macaca mulatta	97.27	0.00e+00	2170.00
IUUC-Meu-056259	Macropus eugenii	85.97	0.00e+00	1979.00
IUUC-Mga-059671	Meleagris gallopavo	84.72	0.00e+00	1975.00
IUUC-Mmr-061003	Microcebus murinus	96.88	0.00e+00	2207.00
IUUC-Mmu-063584	Mus musculus	95.12	0.00e+00	2138.00
IUUC-Mpu-066056	Mustela putorius furo	97.92	0.00e+00	2201.00
IUUC-Mlu-067850	Myotis lucifugus	97.36	0.00e+00	2238.00
IUUC-Nle-069837	Nomascus leucogenys	94.10	0.00e+00	2025.00
IUUC-Opr-070943	Ochotona princeps	93.02	0.00e+00	2048.00
IUUC-Ont-071663	Oreochromis niloticus	66.11	0.00e+00	1517.00
IUUC-Oan-072934	Ornithorhynchus anatinus	75.60	0.00e+00	1259.00
IUUC-Ocu-074706	Oryctolagus cuniculus	96.71	0.00e+00	2225.00
IUUC-Ola-086543	Oryzias latipes	63.28	0.00e+00	1482.00
IUUC-Oga-088671	Otolemur garnettii	85.76	0.00e+00	1020.00
IUUC-Oar-089560	Ovis aries	92.45	0.00e+00	2145.00
IUUC-Ptr-090875	Pan troglodytes	97.19	0.00e+00	2203.00
IUUC-Pan-091788	Papio anubis	94.24	0.00e+00	2125.00
IUUC-Psi-093382	Pelodiscus sinensis	83.97	0.00e+00	1956.00
IUUC-Pma-094687	Petromyzon marinus	56.77	8.00e-92	331.00
IUUC-Pfo-096272	Poecilia formosa	62.53	0.00e+00	1426.00
IUUC-Pab-097907	Pongo abelii	92.46	0.00e+00	2020.00
IUUC-Pca-100628	Procavia capensis	87.55	0.00e+00	1775.00
IUUC-Pva-102956	Pteropus vampyrus	96.94	0.00e+00	1196.00
IUUC-Rno-105722	Rattus norvegicus	95.92	0.00e+00	1823.00
IUUC-Sha-106626	Sarcophilus harrisii	81.75	0.00e+00	1821.00
IUUC-Ssc-115918	Sus scrofa	97.15	0.00e+00	1774.00
IUUC-Tru-118638	Takifugu rubripes	70.24	0.00e+00	933.00
IUUC-Tsy-118820	Tarsius syrichta	92.95	0.00e+00	773.00
IUUC-Tbe-127654	Tupaia belangeri	78.09	0.00e+00	1610.00
IUUC-Ttr-128821	Tursiops truncatus	90.95	0.00e+00	1999.00
IUUC-Xtr-131823	Xenopus tropicalis	75.60	0.00e+00	1674.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence