iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Dme-032028

UUCD1 version

UUC-DrM-00003

Ensembl Protein ID

FBpp0070123

UniProt Accession

O77430; O77430_DROME

Genbank Protein ID

AAF45538.1; AAF45539.1; AAF45540.1; AAF64674.1; AAG22362.1; AAL39442.1; AAN09024.1; AAN09025.1; AAN09026.1; ABC67161.1; ACU43544.1; ACU51754.1; AHN59226.1; ANY27848.1; CAA20889.1

Protein Name

GEO01111p1; HL01263p; RH26825p; SKP1-related A, isoform A; SKP1-related A, isoform B; SKP1-related A, isoform C; SKP1-related A, isoform E; SKP1-related A, isoform F; SKP1-related A, isoform G; SKPA

Genbank Nucleotide ID

AE014298; AE014298; AE014298; AF220066; AE014298; AY069297; AE014298; AE014298; AE014298; AE014298; BT099582; BT099610; AE014298; KX532038; AL031581

Gene Name

SkpA; Dredd; EG:115C2.4; skpA; skpA-RC; skpA-RH; CG16983; Dmel_CG16983

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0025637	FBtr0070128	FBpp0070123

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/SKP1	SKP1	12401167

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/SKP1	1.10e-29	102.4	112	159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/SKP1

   S: 1    ksLLdltcktVadmikgktpeeiRktFnienDftpeEeakvReEnqWA 48
           k+LL+ltcktVa+mikgktpeeiRktFni++Df+p+Ee++vR+En+W+
   Q: 112  KGLLELTCKTVANMIKGKTPEEIRKTFNIKKDFSPAEEEQVRKENEWC 159
           89*********************************************9 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPSIKLQSSD EEIFDTDIQI AKCSGTIKTM LEDCGMEDDE NAIVPLPNVN STILRKVLTW 60
AHYHKDDPQP TEDDESKEKR TDDIISWDAD FLKVDQGTLF ELILAANYLD IKGLLELTCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACCATTCT CTATTCGCCA TTTGAAAGTA TCGGTGTAAT TTGTTTTCAG AGAAATTAAT 60
TTCCGTTTAC TGTGCAATTC GGTGTGAAAG TGTTCAGATT TATCAATGCG TATTCTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR016897--SKP1
IPR001232--SKP1-like
IPR011333--SKP1/BTB/POZ
IPR016072--Skp1_comp_dimer
IPR016073--Skp1_comp_POZ

Pfam

PF01466--Skp1
PF03931--Skp1_POZ

SMART

SM00512--Skp1

Gene Ontology

GO:0005813--C:centrosome
GO:0005875--C:microtubule associated complex
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005819--C:spindle
GO:0051298--P:centrosome duplication
GO:0030261--P:chromosome condensation
GO:0042023--P:DNA endoreduplication
GO:0007095--P:mitotic G2 DNA damage checkpoint
GO:0007067--P:mitotic nuclear division
GO:0043066--P:negative regulation of apoptotic process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046329--P:negative regulation of JNK cascade
GO:0045886--P:negative regulation of synaptic growth at neuromuscular junction
GO:0022008--P:neurogenesis
GO:0016322--P:neuron remodeling
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0010824--P:regulation of centrosome duplication
GO:0010906--P:regulation of glucose metabolic process
GO:0031647--P:regulation of protein stability

KEGG

dme:Dmel_CG16983

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001036	Aegilops tauschii	55.35	8.00e-44	168.00
IUUC-Aml-002023	Ailuropoda melanoleuca	76.69	2.00e-54	203.00
IUUC-Atr-002858	Amborella trichopoda	57.59	3.00e-37	146.00
IUUC-Apl-003393	Anas platyrhynchos	76.69	2.00e-54	203.00
IUUC-Aca-004709	Anolis carolinensis	76.69	2.00e-54	203.00
IUUC-Aly-006066	Arabidopsis lyrata	53.89	2.00e-36	144.00
IUUC-Ath-007281	Arabidopsis thaliana	54.09	2.00e-36	144.00
IUUC-Ago-007847	Ashbya gossypii	42.61	3.00e-36	143.00
IUUC-Acl-008178	Aspergillus clavatus	55.35	1.00e-47	181.00
IUUC-Afl-008452	Aspergillus flavus	54.04	1.00e-47	181.00
IUUC-Afu-008785	Aspergillus fumigatus	55.90	2.00e-48	183.00
IUUC-Ani-009312	Aspergillus nidulans	52.87	3.00e-41	159.00
IUUC-Aor-010012	Aspergillus oryzae	54.04	1.00e-47	181.00
IUUC-Ate-010375	Aspergillus terreus	55.62	4.00e-48	182.00
IUUC-Ame-011025	Astyanax mexicanus	75.46	1.00e-53	201.00
IUUC-Bgr-012280	Blumeria graminis	54.73	2.00e-32	130.00
IUUC-Bta-013519	Bos taurus	76.69	2.00e-54	203.00
IUUC-Bci-013888	Botrytis cinerea	61.16	4.00e-31	126.00
IUUC-Bdi-014206	Brachypodium distachyon	55.21	3.00e-34	136.00
IUUC-Bol-015842	Brassica oleracea	55.97	3.00e-38	149.00
IUUC-Bra-016913	Brassica rapa	55.97	3.00e-38	149.00
IUUC-Cel-018653	Caenorhabditis elegans	64.60	6.00e-53	199.00
IUUC-Cja-019823	Callithrix jacchus	72.67	9.00e-49	184.00
IUUC-Cfa-020931	Canis familiaris	76.07	2.00e-53	200.00
IUUC-Cpo-022487	Cavia porcellus	75.93	6.00e-54	202.00
IUUC-Cre-022751	Chlamydomonas reinhardtii	57.05	9.00e-43	164.00
IUUC-Csa-023459	Chlorocebus sabaeus	76.07	6.00e-54	202.00
IUUC-Cin-025538	Ciona intestinalis	73.46	1.00e-52	197.00
IUUC-Csv-025865	Ciona savignyi	72.84	3.00e-60	223.00
IUUC-Cgl-026548	Colletotrichum gloeosporioides	54.73	5.00e-38	149.00
IUUC-Cne-027058	Cryptococcus neoformans	55.49	1.00e-46	177.00
IUUC-Cme-027174	Cyanidioschyzon merolae	46.50	4.00e-35	139.00
IUUC-Dre-027756	Danio rerio	75.46	1.00e-53	201.00
IUUC-Dno-028924	Dasypus novemcinctus	76.69	2.00e-54	203.00
IUUC-Dor-030847	Dipodomys ordii	72.22	1.00e-55	207.00
IUUC-Dse-031209	Dothistroma septosporum	55.28	4.00e-42	162.00
IUUC-Ete-033117	Echinops telfairi	76.69	3.00e-52	196.00
IUUC-Eca-033320	Equus caballus	76.69	2.00e-54	203.00
IUUC-Fca-035423	Felis catus	76.69	2.00e-54	203.00
IUUC-Fal-036956	Ficedula albicollis	76.69	2.00e-54	203.00
IUUC-Fox-037761	Fusarium oxysporum	56.25	1.00e-39	154.00
IUUC-Fso-038451	Fusarium solani	53.02	3.00e-37	146.00
IUUC-Gmo-039178	Gadus morhua	76.07	4.00e-54	202.00
IUUC-Ggr-039831	Gaeumannomyces graminis	51.02	3.00e-38	150.00
IUUC-Gga-040238	Gallus gallus	76.69	2.00e-54	203.00
IUUC-Gac-041965	Gasterosteus aculeatus	76.07	4.00e-54	202.00
IUUC-Gma-043086	Glycine max	58.86	5.00e-40	155.00
IUUC-Ggo-045025	Gorilla gorilla	76.69	2.00e-54	203.00
IUUC-Hsa-046875	Homo sapiens	76.69	2.00e-54	203.00
IUUC-Hvu-047497	Hordeum vulgare	52.80	1.00e-37	147.00
IUUC-Itr-047900	Ictidomys tridecemlineatus	74.23	2.00e-52	197.00
IUUC-Kpa-049138	Komagataella pastoris	44.51	5.00e-36	142.00
IUUC-Lch-050522	Latimeria chalumnae	75.64	6.00e-56	208.00
IUUC-Lpe-050890	Leersia perrieri	54.88	3.00e-34	136.00
IUUC-Loc-052596	Lepisosteus oculatus	76.07	4.00e-54	202.00
IUUC-Lma-053020	Leptosphaeria maculans	51.39	1.00e-34	137.00
IUUC-Laf-053847	Loxodonta africana	76.69	2.00e-54	203.00
IUUC-Mor-057176	Magnaporthe oryzae	52.78	5.00e-39	152.00
IUUC-Mpo-057471	Magnaporthe poae	51.02	3.00e-38	150.00
IUUC-Mtr-058458	Medicago truncatula	51.90	4.00e-39	152.00
IUUC-Mla-059153	Melampsora laricipopulina	53.12	5.00e-40	155.00
IUUC-Mga-059864	Meleagris gallopavo	76.69	2.00e-54	203.00
IUUC-Mvi-060342	Microbotryum violaceum	54.66	2.00e-43	167.00
IUUC-Mdo-062509	Monodelphis domestica	76.69	2.00e-54	203.00
IUUC-Mmu-063694	Mus musculus	76.07	4.00e-54	202.00
IUUC-Mac-064509	Musa acuminata	58.23	6.00e-41	159.00
IUUC-Mpu-065990	Mustela putorius furo	76.69	2.00e-54	203.00
IUUC-Mlu-068168	Myotis lucifugus	76.69	2.00e-54	203.00
IUUC-Nfi-068309	Neosartorya fischeri	55.90	2.00e-48	183.00
IUUC-Ncr-068658	Neurospora crassa	55.56	2.00e-41	160.00
IUUC-Nle-070101	Nomascus leucogenys	76.69	2.00e-54	203.00
IUUC-Opr-070881	Ochotona princeps	76.69	2.00e-54	203.00
IUUC-Ont-071529	Oreochromis niloticus	76.07	4.00e-54	202.00
IUUC-Oan-072985	Ornithorhynchus anatinus	70.75	1.00e-23	100.00
IUUC-Ocu-073780	Oryctolagus cuniculus	76.69	2.00e-54	203.00
IUUC-Oba-075368	Oryza barthii	47.06	3.00e-33	133.00
IUUC-Obr-076218	Oryza brachyantha	56.17	7.00e-39	152.00
IUUC-Ogl-077679	Oryza glaberrima	47.06	3.00e-33	133.00
IUUC-Ogu-078125	Oryza glumaepatula	48.82	2.00e-33	134.00
IUUC-Oin-079779	Oryza indica	47.65	1.00e-33	134.00
IUUC-Olo-080526	Oryza longistaminata	47.80	2.00e-30	124.00
IUUC-Ome-081330	Oryza meridionalis	47.93	1.00e-33	134.00
IUUC-Oni-082143	Oryza nivara	47.65	1.00e-33	134.00
IUUC-Opu-083354	Oryza punctata	51.79	2.00e-34	137.00
IUUC-Oru-085023	Oryza rufipogon	52.20	2.00e-33	134.00
IUUC-Osa-085416	Oryza sativa	47.65	1.00e-33	134.00
IUUC-Ola-087270	Oryzias latipes	76.07	4.00e-54	202.00
IUUC-Olu-087667	Ostreococcus lucimarinus	55.41	3.00e-44	169.00
IUUC-Oga-089073	Otolemur garnettii	76.69	2.00e-54	203.00
IUUC-Oar-089762	Ovis aries	60.33	1.00e-45	174.00
IUUC-Ptr-090872	Pan troglodytes	72.84	3.00e-52	196.00
IUUC-Pan-091780	Papio anubis	76.69	2.00e-54	203.00
IUUC-Psi-093135	Pelodiscus sinensis	76.69	2.00e-54	203.00
IUUC-Pno-094810	Phaeosphaeria nodorum	53.47	4.00e-33	132.00
IUUC-Ppa-095244	Physcomitrella patens	58.86	3.00e-45	173.00
IUUC-Pfo-097529	Poecilia formosa	76.07	4.00e-54	202.00
IUUC-Pab-098533	Pongo abelii	76.69	2.00e-54	203.00
IUUC-Pop-098957	Populus trichocarpa	59.24	5.00e-40	155.00
IUUC-Pca-100783	Procavia capensis	68.71	7.00e-45	171.00
IUUC-Ppe-101410	Prunus persica	52.17	6.00e-41	158.00
IUUC-Pva-102901	Pteropus vampyrus	76.69	2.00e-54	203.00
IUUC-Ptt-103874	Puccinia triticina	57.46	9.00e-41	159.00
IUUC-Pte-104224	Pyrenophora teres	58.65	8.00e-31	125.00
IUUC-Pyt-104750	Pyrenophora triticirepentis	58.65	4.00e-31	126.00
IUUC-Rno-105499	Rattus norvegicus	76.07	4.00e-54	202.00
IUUC-Sce-106387	Saccharomyces cerevisiae	55.00	3.00e-35	140.00
IUUC-Sja-107902	Schizosaccharomyces japonicus	54.27	8.00e-46	175.00
IUUC-Spo-108033	Schizosaccharomyces pombe	56.71	2.00e-46	176.00
IUUC-Ssl-108591	Sclerotinia sclerotiorum	57.24	2.00e-41	160.00
IUUC-Smo-109307	Selaginella moellendorffii	57.59	9.00e-43	164.00
IUUC-Sit-110435	Setaria italica	52.41	1.00e-35	141.00
IUUC-Sly-111529	Solanum lycopersicum	58.86	2.00e-39	154.00
IUUC-Stu-112611	Solanum tuberosum	56.33	3.00e-39	153.00
IUUC-Sar-112973	Sorex araneus	70.55	2.00e-46	177.00
IUUC-Sbi-114666	Sorghum bicolor	53.01	3.00e-38	149.00
IUUC-Sre-115178	Sporisorium reilianum	58.12	9.00e-49	184.00
IUUC-Tgu-116474	Taeniopygia guttata	76.69	2.00e-54	203.00
IUUC-Tru-118429	Takifugu rubripes	76.69	4.00e-54	202.00
IUUC-Tsy-118896	Tarsius syrichta	76.69	2.00e-54	203.00
IUUC-Tni-119960	Tetraodon nigroviridis	76.69	4.00e-54	202.00
IUUC-Tca-121022	Theobroma cacao	58.86	5.00e-40	155.00
IUUC-Tre-122004	Trichoderma reesei	53.47	2.00e-32	130.00
IUUC-Tvi-122449	Trichoderma virens	53.47	5.00e-33	132.00
IUUC-Tae-125854	Triticum aestivum	55.35	8.00e-44	168.00
IUUC-Tur-126793	Triticum urartu	54.09	1.00e-40	158.00
IUUC-Tme-127078	Tuber melanosporum	53.99	8.00e-41	158.00
IUUC-Tbe-127720	Tupaia belangeri	76.69	2.00e-54	203.00
IUUC-Ttr-129035	Tursiops truncatus	76.69	2.00e-54	203.00
IUUC-Uma-129517	Ustilago maydis	56.88	1.00e-46	177.00
IUUC-Vda-129691	Verticillium dahliae	50.68	4.00e-34	136.00
IUUC-Vpa-130128	Vicugna pacos	76.69	2.00e-54	203.00
IUUC-Vvi-130876	Vitis vinifera	59.75	2.00e-44	170.00
IUUC-Xtr-132393	Xenopus tropicalis	76.69	2.00e-54	203.00
IUUC-Xma-133603	Xiphophorus maculatus	76.07	4.00e-54	202.00
IUUC-Yli-134499	Yarrowia lipolytica	52.44	6.00e-45	172.00
IUUC-Zma-134722	Zea mays	45.29	1.00e-32	132.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence