iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034008

UUCD1 version

UUC-EqC-00230

Ensembl Protein ID

ENSECAP00000013139.1

UniProt Accession

F6TM98; F6TM98_HORSE

Protein Name

Uncharacterized protein

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015506.1	ENSECAT00000016274.1	ENSECAP00000013139.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.77	0.00e+00	668.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MEGGGRPSLG QVILLGTSSV VTAILYSVYR QKAQVAQELK GARRIHLGED LKSILSEAPG 60
KCVPYAVIEG VVRSVKETLN SQFVDNCKGV IQRLTLQEHK MVWNRTTHLW NDCSKIIHQR 120

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Nucleotide Sequence
(Fasta)

CTCCTGGGCA CGGCGCAGCC ATGGAGGGCG GAGGGCGGCC GTCGCTGGGC CAGGTCATCC 60
TCCTGGGCAC CAGCTCTGTC GTCACCGCCA TCCTGTACTC CGTGTACCGG CAGAAGGCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

KEGG

ecb:100058446

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002287	Ailuropoda melanoleuca	90.06	0.00e+00	637.00
IUUC-Atr-002698	Amborella trichopoda	24.44	1.00e-09	57.40
IUUC-Aca-005039	Anolis carolinensis	38.84	2.00e-64	238.00
IUUC-Aly-006181	Arabidopsis lyrata	27.75	2.00e-20	93.20
IUUC-Ath-007438	Arabidopsis thaliana	28.03	2.00e-21	96.70
IUUC-Ame-010671	Astyanax mexicanus	62.22	2.00e-132	465.00
IUUC-Bta-012407	Bos taurus	79.60	5.00e-162	563.00
IUUC-Bdi-014735	Brachypodium distachyon	27.03	1.00e-18	87.00
IUUC-Bol-015493	Brassica oleracea	26.86	2.00e-22	99.80
IUUC-Bra-016933	Brassica rapa	27.63	9.00e-20	90.90
IUUC-Cja-019709	Callithrix jacchus	89.41	9.00e-177	612.00
IUUC-Cfa-020818	Canis familiaris	90.91	0.00e+00	649.00
IUUC-Cpo-022490	Cavia porcellus	88.92	4.00e-178	617.00
IUUC-Csa-023259	Chlorocebus sabaeus	89.77	0.00e+00	668.00
IUUC-Cho-024730	Choloepus hoffmanni	89.20	0.00e+00	657.00
IUUC-Cin-025301	Ciona intestinalis	31.23	4.00e-45	174.00
IUUC-Dre-028644	Danio rerio	62.22	1.00e-134	472.00
IUUC-Dno-028925	Dasypus novemcinctus	88.07	0.00e+00	657.00
IUUC-Dor-030692	Dipodomys ordii	87.22	2.00e-178	618.00
IUUC-Dme-031761	Drosophila melanogaster	30.95	8.00e-33	134.00
IUUC-Ete-032329	Echinops telfairi	78.69	3.00e-149	521.00
IUUC-Eeu-034895	Erinaceus europaeus	77.56	1.00e-121	428.00
IUUC-Fca-036104	Felis catus	90.62	0.00e+00	651.00
IUUC-Fal-036900	Ficedula albicollis	71.72	1.00e-135	476.00
IUUC-Gmo-039049	Gadus morhua	57.95	4.00e-104	371.00
IUUC-Gga-040254	Gallus gallus	71.88	6.00e-144	503.00
IUUC-Gac-042277	Gasterosteus aculeatus	60.23	2.00e-135	475.00
IUUC-Gma-043979	Glycine max	29.52	2.00e-21	96.70
IUUC-Ggo-045509	Gorilla gorilla	89.77	0.00e+00	668.00
IUUC-Hsa-046597	Homo sapiens	89.77	0.00e+00	668.00
IUUC-Hvu-047335	Hordeum vulgare	26.18	1.00e-17	83.60
IUUC-Itr-048691	Ictidomys tridecemlineatus	88.64	4.00e-180	623.00
IUUC-Lch-050344	Latimeria chalumnae	66.48	1.00e-143	502.00
IUUC-Loc-052376	Lepisosteus oculatus	65.62	1.00e-146	511.00
IUUC-Laf-054414	Loxodonta africana	90.06	0.00e+00	666.00
IUUC-Mcc-054604	Macaca mulatta	89.77	0.00e+00	668.00
IUUC-Meu-056087	Macropus eugenii	81.82	4.00e-168	583.00
IUUC-Mtr-057779	Medicago truncatula	27.33	3.00e-18	85.90
IUUC-Mga-060188	Meleagris gallopavo	72.76	2.00e-141	494.00
IUUC-Mmr-060704	Microcebus murinus	90.06	0.00e+00	667.00
IUUC-Mdo-062842	Monodelphis domestica	80.68	6.00e-159	553.00
IUUC-Mmu-064324	Mus musculus	86.65	9.00e-174	602.00
IUUC-Mpu-065940	Mustela putorius furo	88.07	1.00e-176	612.00
IUUC-Mlu-067028	Myotis lucifugus	89.77	0.00e+00	666.00
IUUC-Nle-069254	Nomascus leucogenys	82.77	7.00e-178	615.00
IUUC-Opr-070827	Ochotona princeps	84.38	0.00e+00	627.00
IUUC-Ont-072008	Oreochromis niloticus	61.08	2.00e-138	485.00
IUUC-Oan-072935	Ornithorhynchus anatinus	77.84	6.00e-165	573.00
IUUC-Ocu-074526	Oryctolagus cuniculus	89.20	1.00e-178	618.00
IUUC-Obr-076592	Oryza brachyantha	27.25	5.00e-21	94.70
IUUC-Ogl-077732	Oryza glaberrima	27.62	9.00e-21	94.00
IUUC-Oin-080188	Oryza indica	27.62	9.00e-21	94.00
IUUC-Olo-080705	Oryza longistaminata	24.90	1.00e-13	70.90
IUUC-Ola-087288	Oryzias latipes	57.39	1.00e-127	449.00
IUUC-Oga-088402	Otolemur garnettii	89.49	0.00e+00	664.00
IUUC-Oar-089851	Ovis aries	91.93	2.00e-87	314.00
IUUC-Ptr-091226	Pan troglodytes	89.49	0.00e+00	667.00
IUUC-Pan-092575	Papio anubis	89.49	0.00e+00	667.00
IUUC-Psi-094062	Pelodiscus sinensis	75.28	6.00e-163	566.00
IUUC-Pma-094501	Petromyzon marinus	37.50	1.00e-43	170.00
IUUC-Ppa-095285	Physcomitrella patens	25.16	9.00e-14	70.90
IUUC-Pfo-096146	Poecilia formosa	56.53	3.00e-121	427.00
IUUC-Pab-098524	Pongo abelii	89.49	0.00e+00	667.00
IUUC-Pop-099864	Populus trichocarpa	29.45	3.00e-19	89.40
IUUC-Pca-100314	Procavia capensis	90.06	0.00e+00	662.00
IUUC-Ppe-101663	Prunus persica	26.20	2.00e-16	80.10
IUUC-Pva-102947	Pteropus vampyrus	90.34	0.00e+00	667.00
IUUC-Rno-105024	Rattus norvegicus	86.36	7.00e-177	612.00
IUUC-Sha-107500	Sarcophilus harrisii	68.89	2.00e-119	421.00
IUUC-Smo-109194	Selaginella moellendorffii	27.57	1.00e-18	87.00
IUUC-Sit-109922	Setaria italica	26.82	7.00e-20	91.30
IUUC-Sly-111826	Solanum lycopersicum	27.54	2.00e-19	90.10
IUUC-Stu-112907	Solanum tuberosum	27.16	9.00e-19	87.40
IUUC-Sar-113522	Sorex araneus	89.10	5.00e-166	576.00
IUUC-Sbi-114536	Sorghum bicolor	27.41	6.00e-21	94.70
IUUC-Ssc-115445	Sus scrofa	92.05	0.00e+00	629.00
IUUC-Tgu-116551	Taeniopygia guttata	71.88	4.00e-134	470.00
IUUC-Tru-118407	Takifugu rubripes	56.25	3.00e-113	401.00
IUUC-Tsy-118794	Tarsius syrichta	86.93	0.00e+00	639.00
IUUC-Tni-120128	Tetraodon nigroviridis	62.71	4.00e-92	330.00
IUUC-Tca-121508	Theobroma cacao	27.79	1.00e-20	94.00
IUUC-Tae-125185	Triticum aestivum	26.61	1.00e-20	94.00
IUUC-Tur-126470	Triticum urartu	26.32	1.00e-20	93.60
IUUC-Tbe-127432	Tupaia belangeri	88.35	6.00e-177	612.00
IUUC-Ttr-128573	Tursiops truncatus	89.20	0.00e+00	637.00
IUUC-Vpa-130583	Vicugna pacos	89.42	4.00e-171	593.00
IUUC-Vvi-131710	Vitis vinifera	27.17	1.00e-15	77.40
IUUC-Xtr-132009	Xenopus tropicalis	59.32	3.00e-130	457.00
IUUC-Xma-134121	Xiphophorus maculatus	57.22	6.00e-128	450.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence