iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004287

Ensembl Protein ID

ENSACAP00000013537.3

UniProt Accession

G1KP67; G1KP67_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000013548.3	ENSACAT00000013815.3	ENSACAP00000013537.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.10e-62	206.0	1231	1283

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g +GlfP+n+v+ 
   Q: 1231 QVIAMYDYLANNEDELSFSKGQLINVL--NKDDLDWWQG--EINGISGLFPSNYVKM 1283
           6899***********************..78899*****..9*************85 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MMAQILTGIN GGPNMWAITS EERMKYDKQF DSLKPIGGYV TGDQARMFFL QSGLPSTILA 60
EIWALSDLNK DGKMDKQEFS IAMKLIKLKL QGQPLPVVLP PVMKQSPVFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCAGATG GCTGACAGCT AGCAAGAAAC ACTCAGGATC ATGATGGCAC AGATTCTTAC 60
AGGCATAAAT GGTAAGTAGC TTACTTAGGA CGTGTTCTGA AGGTAAGGCA CTGTATTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

acs:100553623

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	85.62	0.00e+00	1662.00
IUUC-Ame-011759	Astyanax mexicanus	63.17	0.00e+00	1255.00
IUUC-Bta-013248	Bos taurus	83.63	0.00e+00	1609.00
IUUC-Cel-018490	Caenorhabditis elegans	32.38	3.00e-53	203.00
IUUC-Cfa-020628	Canis familiaris	85.62	0.00e+00	1672.00
IUUC-Csa-023122	Chlorocebus sabaeus	84.80	0.00e+00	1644.00
IUUC-Cne-026918	Cryptococcus neoformans	36.64	2.00e-38	155.00
IUUC-Cme-027247	Cyanidioschyzon merolae	27.53	1.00e-10	61.20
IUUC-Dre-027849	Danio rerio	63.85	0.00e+00	1201.00
IUUC-Dno-029419	Dasypus novemcinctus	84.36	0.00e+00	1648.00
IUUC-Dor-030504	Dipodomys ordii	71.25	0.00e+00	1342.00
IUUC-Dme-032099	Drosophila melanogaster	33.48	4.00e-56	213.00
IUUC-Eca-034196	Equus caballus	82.00	0.00e+00	1568.00
IUUC-Eeu-034972	Erinaceus europaeus	61.91	1.00e-163	571.00
IUUC-Fca-035757	Felis catus	86.05	0.00e+00	1675.00
IUUC-Fal-037531	Ficedula albicollis	78.46	0.00e+00	2028.00
IUUC-Gga-041012	Gallus gallus	84.65	0.00e+00	1667.00
IUUC-Ggo-045405	Gorilla gorilla	71.50	0.00e+00	1808.00
IUUC-Hsa-046833	Homo sapiens	84.91	0.00e+00	1643.00
IUUC-Lch-050094	Latimeria chalumnae	78.25	0.00e+00	1516.00
IUUC-Loc-052646	Lepisosteus oculatus	72.92	0.00e+00	1441.00
IUUC-Mcc-054709	Macaca mulatta	84.91	0.00e+00	1645.00
IUUC-Meu-056396	Macropus eugenii	76.75	0.00e+00	1461.00
IUUC-Mla-059128	Melampsora laricipopulina	34.20	6.00e-40	160.00
IUUC-Mga-059997	Meleagris gallopavo	85.62	0.00e+00	1732.00
IUUC-Mvi-060268	Microbotryum violaceum	28.94	1.00e-43	172.00
IUUC-Mmr-060891	Microcebus murinus	84.66	0.00e+00	1682.00
IUUC-Mmu-064226	Mus musculus	82.03	0.00e+00	1645.00
IUUC-Mpu-066431	Mustela putorius furo	85.30	0.00e+00	1663.00
IUUC-Mlu-068190	Myotis lucifugus	84.47	0.00e+00	1675.00
IUUC-Nle-070116	Nomascus leucogenys	80.82	0.00e+00	1224.00
IUUC-Ola-086482	Oryzias latipes	60.04	0.00e+00	1210.00
IUUC-Oga-088449	Otolemur garnettii	84.56	0.00e+00	1640.00
IUUC-Oar-090275	Ovis aries	84.17	0.00e+00	1629.00
IUUC-Ptr-091667	Pan troglodytes	84.59	0.00e+00	1636.00
IUUC-Pan-091723	Papio anubis	83.83	0.00e+00	1365.00
IUUC-Psi-093136	Pelodiscus sinensis	83.88	0.00e+00	1685.00
IUUC-Pab-098755	Pongo abelii	81.93	0.00e+00	1573.00
IUUC-Pca-101134	Procavia capensis	77.50	0.00e+00	1351.00
IUUC-Pva-102433	Pteropus vampyrus	74.76	0.00e+00	1414.00
IUUC-Pgr-103473	Puccinia graminis	31.36	1.00e-37	153.00
IUUC-Rno-105691	Rattus norvegicus	84.24	0.00e+00	1692.00
IUUC-Sar-112978	Sorex araneus	81.29	0.00e+00	971.00
IUUC-Ssc-115562	Sus scrofa	77.39	0.00e+00	1489.00
IUUC-Tgu-116758	Taeniopygia guttata	86.25	0.00e+00	1707.00
IUUC-Tbe-127477	Tupaia belangeri	81.80	0.00e+00	679.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence