iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010896

Ensembl Protein ID

ENSAMXP00000004337.1

UniProt Accession

W5K9S6; W5K9S6_ASTMX

Genbank Protein ID

ENSAMXP00000004337

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01020624

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000004241.1	ENSAMXT00000004337.1	ENSAMXP00000004337.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-67	226.7	39	466

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ L+++p++ + l + ++++    +++e++++l+ +l +l+++l      ++ + +   ll+al+    ++s++
   Q: 39   GLLNLGNTCFMNSLLQGLAACPSFVRWLEDFESQSSISLARPETDTRLSITLLQLLKALSshePVEDDVLDAGCLLEALRLHRWHISSF 127
           9*****************************777777788899*****************855455566888888*************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk..........slisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E++++l ++leee    ++ +++++++ ++ e+s e++ek  +  +             ++ F+g+l+s + c++c+++s +r
   Q: 128  EEQDAHELFHVLTSSLEEER--DQQPKVTHLFDMETLEKSAESSEKAISCRSrgplhpipslWRTQHPFHGRLTSYMACKRCERQSpVR 214
           *******************9..77888999999998888888888877777778888888878899*********************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqe.............aekklklkklPevLilhLkRfsfse 241
           +++f +lsl++p  +   + +l++cL++f + e++++   ++ce+c+k q+               k+lkl klP++L++hL+R ++s 
   Q: 215  YDSFDSLSLSIPAVQWGRPVTLDQCLQHFISSETIKE---VECENCTKTQTgelvngqesqrttFIKQLKLGKLPQCLCIHLQRLTWST 300
           ***********************************97...9******77778888888888888***********************99 PP
   S: 242  eqksrekinkkvefpleLdlsp..fcts.....peekqke................................................. 274
           e + ++k +++v+f + L++++  +c+      +                                                       
   Q: 301  E-GTPIKRQEHVQFSEYLSMDRykHCSAaqrlqK-----Psrankpsstgatadahdqtvangldpehhnnnkplsngafpsvfihsps 383
           8.999***********9***97225555555550.....25555556666666666666666777777777778888888888888888 PP
   S: 275  ..............kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                         ++ ++L+av+vH+G ++sGH+++y +           + +Wl ++D++V++ + +e l+   s+aY+lfY+r
   Q: 384  lspqlnltydysssEYLFRLTAVLVHHGDMHSGHFITYRRGppsprstapFSPQWLWVSDDSVRKASLQEALS---SSAYLLFYER 466
           888888888888889**************************8887777666777*******************...********98 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MMKNWGLIGG IAAAMAAGVY VLWGPITDRK KKRKGTVPGL LNLGNTCFMN SLLQGLAACP 60
SFVRWLEDFE SQSSISLARP ETDTRLSITL LQLLKALSSH EPVEDDVLDA GCLLEALRLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCAATTG AGACGCACCC CTTCTGAATG TGTTGTAGGC GGAATAGCCG AGTGCCCTAC 60
AACATTTGTG CGCACTCCAG GGTGCGGGCG CGTATTGGAA CGCGCCCCGT CGTGTCGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	25.50	7.00e-15	75.50
IUUC-Aml-001733	Ailuropoda melanoleuca	60.46	2.00e-149	521.00
IUUC-Atr-002510	Amborella trichopoda	25.39	2.00e-23	104.00
IUUC-Apl-003645	Anas platyrhynchos	58.84	3.00e-80	291.00
IUUC-Aca-004583	Anolis carolinensis	65.67	3.00e-22	95.90
IUUC-Aly-005754	Arabidopsis lyrata	26.82	6.00e-21	95.50
IUUC-Ath-007622	Arabidopsis thaliana	26.26	2.00e-24	107.00
IUUC-Acl-008136	Aspergillus clavatus	22.62	3.00e-15	77.00
IUUC-Ani-009286	Aspergillus nidulans	22.05	6.00e-15	75.90
IUUC-Bta-012321	Bos taurus	61.05	1.00e-150	526.00
IUUC-Bdi-014795	Brachypodium distachyon	25.95	2.00e-21	97.10
IUUC-Bol-015637	Brassica oleracea	24.48	7.00e-23	101.00
IUUC-Bra-016801	Brassica rapa	26.24	4.00e-22	99.40
IUUC-Cel-018308	Caenorhabditis elegans	29.39	5.00e-40	158.00
IUUC-Cja-018826	Callithrix jacchus	61.75	1.00e-155	542.00
IUUC-Cfa-021206	Canis familiaris	61.30	2.00e-150	525.00
IUUC-Cpo-021343	Cavia porcellus	61.84	4.00e-152	531.00
IUUC-Csa-023419	Chlorocebus sabaeus	61.88	9.00e-156	543.00
IUUC-Cho-024475	Choloepus hoffmanni	52.30	1.00e-78	286.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.47	2.00e-12	68.20
IUUC-Cne-027061	Cryptococcus neoformans	27.43	2.00e-13	71.20
IUUC-Dre-027563	Danio rerio	81.84	0.00e+00	771.00
IUUC-Dno-029929	Dasypus novemcinctus	61.60	5.00e-152	531.00
IUUC-Dor-030166	Dipodomys ordii	53.47	2.00e-122	432.00
IUUC-Dme-031627	Drosophila melanogaster	33.77	1.00e-35	144.00
IUUC-Ete-032634	Echinops telfairi	59.67	4.00e-143	501.00
IUUC-Eca-033968	Equus caballus	61.68	8.00e-154	536.00
IUUC-Eeu-035279	Erinaceus europaeus	63.80	2.00e-44	173.00
IUUC-Fca-036525	Felis catus	60.76	1.00e-155	543.00
IUUC-Fal-036606	Ficedula albicollis	61.60	8.00e-125	439.00
IUUC-Gmo-038726	Gadus morhua	66.39	4.00e-168	584.00
IUUC-Gga-040718	Gallus gallus	61.86	8.00e-125	439.00
IUUC-Gac-042645	Gasterosteus aculeatus	70.85	0.00e+00	631.00
IUUC-Gma-042890	Glycine max	23.91	6.00e-21	95.50
IUUC-Ggo-045021	Gorilla gorilla	62.92	2.00e-156	545.00
IUUC-Hsa-045832	Homo sapiens	62.92	2.00e-156	545.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	62.11	2.00e-152	531.00
IUUC-Kpa-049268	Komagataella pastoris	21.49	2.00e-18	87.00
IUUC-Lch-050662	Latimeria chalumnae	63.83	3.00e-166	578.00
IUUC-Lpe-051078	Leersia perrieri	25.92	2.00e-29	123.00
IUUC-Loc-052611	Lepisosteus oculatus	70.70	0.00e+00	642.00
IUUC-Laf-053752	Loxodonta africana	61.47	1.00e-152	532.00
IUUC-Mcc-054892	Macaca mulatta	62.71	3.00e-156	545.00
IUUC-Meu-056673	Macropus eugenii	56.35	3.00e-111	395.00
IUUC-Mor-057143	Magnaporthe oryzae	23.32	2.00e-12	68.20
IUUC-Mtr-057976	Medicago truncatula	27.68	2.00e-31	130.00
IUUC-Mla-058970	Melampsora laricipopulina	25.21	6.00e-27	115.00
IUUC-Mga-059543	Meleagris gallopavo	62.16	5.00e-146	510.00
IUUC-Mmr-061534	Microcebus murinus	61.26	8.00e-156	543.00
IUUC-Mdo-062140	Monodelphis domestica	52.64	2.00e-128	452.00
IUUC-Mmu-063673	Mus musculus	61.51	7.00e-152	530.00
IUUC-Mpu-066328	Mustela putorius furo	60.95	1.00e-154	539.00
IUUC-Mlu-067938	Myotis lucifugus	60.55	7.00e-155	540.00
IUUC-Nle-069426	Nomascus leucogenys	60.92	4.00e-142	498.00
IUUC-Opr-070796	Ochotona princeps	54.88	2.00e-67	249.00
IUUC-Ont-072248	Oreochromis niloticus	74.36	0.00e+00	653.00
IUUC-Oan-072916	Ornithorhynchus anatinus	62.92	2.00e-159	555.00
IUUC-Ocu-074459	Oryctolagus cuniculus	57.73	3.00e-125	441.00
IUUC-Oba-075765	Oryza barthii	25.71	5.00e-31	129.00
IUUC-Obr-076005	Oryza brachyantha	27.31	4.00e-31	129.00
IUUC-Ogl-077916	Oryza glaberrima	26.59	2.00e-34	140.00
IUUC-Ogu-078263	Oryza glumaepatula	25.90	4.00e-31	129.00
IUUC-Oin-080096	Oryza indica	26.10	4.00e-23	102.00
IUUC-Ome-081928	Oryza meridionalis	27.24	3.00e-30	126.00
IUUC-Oni-082424	Oryza nivara	25.90	7.00e-31	128.00
IUUC-Oru-085117	Oryza rufipogon	25.90	7.00e-31	128.00
IUUC-Ola-087429	Oryzias latipes	70.27	1.00e-169	588.00
IUUC-Oga-087981	Otolemur garnettii	61.05	8.00e-155	540.00
IUUC-Oar-089927	Ovis aries	61.47	6.00e-152	530.00
IUUC-Ptr-090878	Pan troglodytes	62.92	2.00e-156	545.00
IUUC-Pan-092698	Papio anubis	62.71	3.00e-156	545.00
IUUC-Psi-093451	Pelodiscus sinensis	62.22	2.00e-158	551.00
IUUC-Ppa-096015	Physcomitrella patens	22.11	1.00e-08	55.10
IUUC-Pfo-096096	Poecilia formosa	73.73	3.00e-179	621.00
IUUC-Pab-098676	Pongo abelii	61.25	2.00e-152	532.00
IUUC-Pca-100418	Procavia capensis	67.18	2.00e-90	326.00
IUUC-Ppe-101898	Prunus persica	24.07	2.00e-24	107.00
IUUC-Pva-103018	Pteropus vampyrus	59.62	2.00e-146	512.00
IUUC-Pgr-103686	Puccinia graminis	22.75	3.00e-12	67.00
IUUC-Pte-104330	Pyrenophora teres	22.96	1.00e-16	81.60
IUUC-Pyt-104518	Pyrenophora triticirepentis	23.48	2.00e-19	91.30
IUUC-Rno-105708	Rattus norvegicus	61.22	2.00e-151	528.00
IUUC-Sha-106971	Sarcophilus harrisii	60.74	2.00e-158	552.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	21.69	3.00e-18	87.00
IUUC-Sit-110442	Setaria italica	27.56	8.00e-27	115.00
IUUC-Sbi-113851	Sorghum bicolor	36.49	2.00e-09	55.80
IUUC-Ssc-116397	Sus scrofa	60.63	3.00e-150	525.00
IUUC-Tgu-117446	Taeniopygia guttata	59.51	4.00e-159	554.00
IUUC-Tru-118268	Takifugu rubripes	66.53	4.00e-163	567.00
IUUC-Tsy-119484	Tarsius syrichta	80.00	2.00e-30	127.00
IUUC-Tni-119735	Tetraodon nigroviridis	66.96	3.00e-147	514.00
IUUC-Tca-121660	Theobroma cacao	26.43	2.00e-30	127.00
IUUC-Tae-125203	Triticum aestivum	24.90	1.00e-26	114.00
IUUC-Tur-126458	Triticum urartu	26.09	3.00e-16	80.10
IUUC-Tbe-127740	Tupaia belangeri	55.88	1.00e-132	466.00
IUUC-Ttr-129273	Tursiops truncatus	60.89	1.00e-149	523.00
IUUC-Vda-129789	Verticillium dahliae	21.91	1.00e-11	65.10
IUUC-Vvi-131177	Vitis vinifera	25.43	7.00e-26	112.00
IUUC-Xtr-132374	Xenopus tropicalis	61.47	5.00e-163	567.00
IUUC-Xma-133267	Xiphophorus maculatus	74.26	0.00e+00	671.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence