• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-047007
Ensembl Protein ID ENSP00000261655.4
UniProt Accession O15034; Q96ID2; RIMB2_HUMAN
Genbank Protein ID BAA20776.1; CAE46066.1; AAH07632.1
Protein Name RIMS-binding protein 2
Genbank Nucleotide ID AB002316; BX641152; AC063926
Gene Name RIMBP2; KIAA0318; RBP2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000060709.14 ENST00000261655.8 ENSP00000261655.4
ENSG00000060709.14 ENST00000540658.1 ENSP00000439437.1
ENSG00000060709.14 ENST00000535703.5 ENSP00000440347.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 9.90e-22 78.3 955 1018
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 4    ekvqvlydyeaqn.......ddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++ +lydy++ +       + eLt+  Gd+++v   e  + g  +g  el+g++Gl+P+nF e++ 
   Q: 955  RRMVALYDYDPREsspnvdvEAELTFCTGDIITVF-GEIDEDGFYYG--ELNGQKGLVPSNFLEEVP 1018
           578899***9987333333346************9.999999*****..9*************9985 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.
 Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.
Protein Sequence
(Fasta)
MREAAERRQQ LQLEHDQALA VLSAKQQEID LLQKSKVREL EEKCRTQSEQ FNLLSRDLEK 60
FRQHAGKIDL LGGSAVAPLD ISTAPSKPFP QFMNGLATSL GKGQESAIGG SSAIGEYIRP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-047007|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAAATGAAC TGAAGGATGC CACCCAGGGA GAGTATCTCC TGAGATCCCA TCATGCAGGC 60
CTTCCCACAA GGGCCCGGCA GCATGACAAG GTAGCTGATA CCACTGTCCA CAGACCATCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-047007|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0965--Cell junction
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
KW-0770--Synapse
Interpro

IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS50853--FN3
PS50002--SH3
Pfam

PF07653--SH3_2
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00060--FN3
SM00326--SH3
Gene Ontology

GO:0030054--C:cell junction
GO:0005886--C:plasma membrane
GO:0045202--C:synapse
GO:0010923--P:negative regulation of phosphatase activity
KEGG hsa:23504
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001784 Ailuropoda melanoleuca 90.52 0.00e+00 796.00
IUUC-Apl-003375 Anas platyrhynchos 79.29 0.00e+00 1151.00
IUUC-Aca-005066 Anolis carolinensis 73.12 0.00e+00 1461.00
IUUC-Ame-010866 Astyanax mexicanus 58.16 0.00e+00 738.00
IUUC-Bta-013134 Bos taurus 85.52 0.00e+00 1208.00
IUUC-Cja-019313 Callithrix jacchus 96.02 0.00e+00 980.00
IUUC-Cfa-020985 Canis familiaris 84.78 0.00e+00 1194.00
IUUC-Cpo-021501 Cavia porcellus 82.21 0.00e+00 1232.00
IUUC-Csa-023054 Chlorocebus sabaeus 98.69 0.00e+00 1540.00
IUUC-Cme-027177 Cyanidioschyzon merolae 57.14 9.90e-01 27.70
IUUC-Dre-028295 Danio rerio 53.77 0.00e+00 962.00
IUUC-Dno-029819 Dasypus novemcinctus 69.37 0.00e+00 699.00
IUUC-Dme-032173 Drosophila melanogaster 36.40 4.00e-53 204.00
IUUC-Ete-032529 Echinops telfairi 72.01 0.00e+00 1352.00
IUUC-Eca-034034 Equus caballus 87.38 0.00e+00 1281.00
IUUC-Fca-035519 Felis catus 67.31 0.00e+00 953.00
IUUC-Fal-036780 Ficedula albicollis 73.21 0.00e+00 1065.00
IUUC-Gmo-039149 Gadus morhua 57.14 0.00e+00 629.00
IUUC-Gga-040811 Gallus gallus 79.21 0.00e+00 1167.00
IUUC-Gac-042154 Gasterosteus aculeatus 57.84 1.00e-178 620.00
IUUC-Ggo-044850 Gorilla gorilla 94.01 0.00e+00 1821.00
IUUC-Itr-048260 Ictidomys tridecemlineatus 84.95 0.00e+00 1648.00
IUUC-Lch-050208 Latimeria chalumnae 69.50 0.00e+00 1019.00
IUUC-Loc-051836 Lepisosteus oculatus 54.03 0.00e+00 766.00
IUUC-Laf-053657 Loxodonta africana 84.04 0.00e+00 1613.00
IUUC-Mcc-055422 Macaca mulatta 98.10 0.00e+00 1929.00
IUUC-Mga-060023 Meleagris gallopavo 70.03 0.00e+00 930.00
IUUC-Mdo-061893 Monodelphis domestica 81.57 0.00e+00 1183.00
IUUC-Mmu-063931 Mus musculus 84.05 0.00e+00 1611.00
IUUC-Mpu-065941 Mustela putorius furo 67.89 0.00e+00 921.00
IUUC-Nle-069981 Nomascus leucogenys 84.10 0.00e+00 1612.00
IUUC-Ont-072190 Oreochromis niloticus 61.14 0.00e+00 806.00
IUUC-Oan-073459 Ornithorhynchus anatinus 69.59 3.00e-117 416.00
IUUC-Ocu-074373 Oryctolagus cuniculus 77.29 0.00e+00 1110.00
IUUC-Ola-087451 Oryzias latipes 59.26 0.00e+00 713.00
IUUC-Oga-088056 Otolemur garnettii 80.61 0.00e+00 932.00
IUUC-Oar-090028 Ovis aries 81.61 0.00e+00 1156.00
IUUC-Pan-092794 Papio anubis 98.88 0.00e+00 1677.00
IUUC-Psi-093107 Pelodiscus sinensis 74.70 0.00e+00 1124.00
IUUC-Pfo-096786 Poecilia formosa 58.96 0.00e+00 768.00
IUUC-Pab-097556 Pongo abelii 97.43 0.00e+00 1927.00
IUUC-Pva-102492 Pteropus vampyrus 83.07 0.00e+00 818.00
IUUC-Rno-105643 Rattus norvegicus 84.26 0.00e+00 1049.00
IUUC-Sha-107544 Sarcophilus harrisii 79.04 0.00e+00 1618.00
IUUC-Ssc-115822 Sus scrofa 66.36 0.00e+00 859.00
IUUC-Tgu-116637 Taeniopygia guttata 77.16 0.00e+00 1041.00
IUUC-Tru-118109 Takifugu rubripes 56.16 1.00e-177 617.00
IUUC-Tni-120805 Tetraodon nigroviridis 62.32 0.00e+00 1231.00
IUUC-Xtr-132230 Xenopus tropicalis 45.67 1.00e-157 551.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved