iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042498

Ensembl Protein ID

ENSGACP00000000134.1

UniProt Accession

G3N4B4; G3N4B4_GASAC

Protein Name

Uncharacterized protein

Gene Name

ARHGEF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000000105.1	ENSGACT00000000134.1	ENSGACP00000000134.1
ENSGACG00000000105.1	ENSGACT00000000136.1	ENSGACP00000000136.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-10	41.3	61	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + ++l+d    +d eL +k+Gdv++v+  + ++++W+ g       +G fP+ Fv+
   Q: 61   YAEALWDHVTMDDQELGFKAGDVIEVV--DATNKEWWWG--RIMDSEGWFPASFVR 112
           5789***********************..9999******..8************97 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

SASVVPDGAS DKAGLGEELG SEDDLLYEDF RSCGHRFGHP GGGGGEQLAI NELISDGSVV 60
YAEALWDHVT MDDQELGFKA GDVIEVVDAT NKEWWWGRIM DSEGWFPASF VRLRVNQDEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGCATCGG TCGTACCTGA CGGGGCTTCA GACAAGGCAG GACTTGGGGA GGAGCTCGGC 60
AGCGAAGATG ATCTGCTGTA TGAAGACTTC CGTAGTTGCG GCCATCGTTT TGGTCACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00621--RhoGEF
PF00018--SH3_1

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002073	Ailuropoda melanoleuca	63.33	0.00e+00	702.00
IUUC-Apl-004117	Anas platyrhynchos	63.40	0.00e+00	719.00
IUUC-Aca-004793	Anolis carolinensis	64.89	0.00e+00	707.00
IUUC-Ago-008003	Ashbya gossypii	31.73	1.00e-15	78.60
IUUC-Ang-009549	Aspergillus niger	26.59	7.00e-18	86.30
IUUC-Ame-010682	Astyanax mexicanus	52.09	4.00e-167	582.00
IUUC-Bgr-012058	Blumeria graminis	25.49	1.00e-16	82.00
IUUC-Bta-013253	Bos taurus	71.38	0.00e+00	821.00
IUUC-Bci-013634	Botrytis cinerea	26.05	3.00e-16	80.90
IUUC-Cja-019555	Callithrix jacchus	62.98	0.00e+00	685.00
IUUC-Cfa-020578	Canis familiaris	63.68	0.00e+00	708.00
IUUC-Cpo-021726	Cavia porcellus	33.01	4.00e-20	94.40
IUUC-Csa-023331	Chlorocebus sabaeus	71.48	0.00e+00	827.00
IUUC-Cho-025069	Choloepus hoffmanni	37.13	3.00e-54	207.00
IUUC-Cin-025453	Ciona intestinalis	45.75	2.00e-122	432.00
IUUC-Csv-025922	Ciona savignyi	46.73	1.00e-96	347.00
IUUC-Dre-028197	Danio rerio	82.57	0.00e+00	952.00
IUUC-Dno-029679	Dasypus novemcinctus	63.16	0.00e+00	679.00
IUUC-Dor-030739	Dipodomys ordii	71.86	0.00e+00	828.00
IUUC-Dme-031672	Drosophila melanogaster	30.36	4.00e-22	100.00
IUUC-Ete-032545	Echinops telfairi	38.67	9.00e-45	176.00
IUUC-Eca-034299	Equus caballus	62.04	0.00e+00	684.00
IUUC-Eeu-034720	Erinaceus europaeus	37.43	2.00e-55	212.00
IUUC-Fca-036416	Felis catus	64.18	0.00e+00	642.00
IUUC-Fal-037035	Ficedula albicollis	62.87	0.00e+00	709.00
IUUC-Gmo-039587	Gadus morhua	88.03	0.00e+00	971.00
IUUC-Gga-040841	Gallus gallus	78.66	0.00e+00	902.00
IUUC-Ggo-044700	Gorilla gorilla	37.43	2.00e-56	215.00
IUUC-Hsa-045681	Homo sapiens	63.71	0.00e+00	654.00
IUUC-Itr-048380	Ictidomys tridecemlineatus	63.16	0.00e+00	686.00
IUUC-Kpa-049278	Komagataella pastoris	29.30	4.00e-20	93.60
IUUC-Lch-049639	Latimeria chalumnae	75.77	0.00e+00	839.00
IUUC-Loc-051994	Lepisosteus oculatus	85.19	0.00e+00	958.00
IUUC-Laf-054307	Loxodonta africana	64.39	0.00e+00	725.00
IUUC-Mcc-055305	Macaca mulatta	65.08	9.00e-141	493.00
IUUC-Meu-056376	Macropus eugenii	77.46	0.00e+00	735.00
IUUC-Mla-059044	Melampsora laricipopulina	25.62	2.00e-21	98.20
IUUC-Mga-059644	Meleagris gallopavo	62.17	0.00e+00	701.00
IUUC-Mvi-060486	Microbotryum violaceum	29.28	3.00e-25	110.00
IUUC-Mmr-061664	Microcebus murinus	62.43	0.00e+00	660.00
IUUC-Mdo-062404	Monodelphis domestica	37.13	8.00e-56	213.00
IUUC-Mmu-063143	Mus musculus	37.72	6.00e-57	216.00
IUUC-Mpu-066851	Mustela putorius furo	63.68	0.00e+00	671.00
IUUC-Mlu-066956	Myotis lucifugus	63.68	0.00e+00	683.00
IUUC-Nle-069174	Nomascus leucogenys	39.83	5.00e-41	161.00
IUUC-Opr-070209	Ochotona princeps	62.48	0.00e+00	678.00
IUUC-Ont-072637	Oreochromis niloticus	89.10	0.00e+00	994.00
IUUC-Oan-073722	Ornithorhynchus anatinus	59.62	0.00e+00	662.00
IUUC-Ocu-074885	Oryctolagus cuniculus	63.24	0.00e+00	663.00
IUUC-Ola-087155	Oryzias latipes	35.56	2.00e-53	204.00
IUUC-Oga-088758	Otolemur garnettii	62.68	0.00e+00	686.00
IUUC-Oar-089923	Ovis aries	71.55	0.00e+00	827.00
IUUC-Ptr-091555	Pan troglodytes	62.63	0.00e+00	703.00
IUUC-Pan-092037	Papio anubis	62.98	0.00e+00	712.00
IUUC-Psi-093865	Pelodiscus sinensis	64.57	0.00e+00	733.00
IUUC-Pfo-096918	Poecilia formosa	35.96	5.00e-53	203.00
IUUC-Pab-097910	Pongo abelii	62.81	0.00e+00	710.00
IUUC-Pca-100891	Procavia capensis	37.90	3.00e-52	201.00
IUUC-Pva-102967	Pteropus vampyrus	65.11	3.00e-151	528.00
IUUC-Pgr-103400	Puccinia graminis	26.74	1.00e-23	105.00
IUUC-Rno-105479	Rattus norvegicus	36.10	2.00e-53	205.00
IUUC-Sce-106197	Saccharomyces cerevisiae	32.85	6.00e-20	92.80
IUUC-Sha-107592	Sarcophilus harrisii	62.98	0.00e+00	701.00
IUUC-Sja-107728	Schizosaccharomyces japonicus	25.09	3.00e-10	60.80
IUUC-Spo-108284	Schizosaccharomyces pombe	30.58	9.00e-20	92.40
IUUC-Ssl-108541	Sclerotinia sclerotiorum	25.95	3.00e-16	80.90
IUUC-Sar-113369	Sorex araneus	67.21	1.00e-121	429.00
IUUC-Sre-115126	Sporisorium reilianum	30.37	3.00e-23	104.00
IUUC-Tgu-117088	Taeniopygia guttata	79.26	0.00e+00	910.00
IUUC-Tru-118716	Takifugu rubripes	36.05	9.00e-55	209.00
IUUC-Tsy-118846	Tarsius syrichta	64.20	2.00e-130	458.00
IUUC-Tni-120887	Tetraodon nigroviridis	36.47	4.00e-54	207.00
IUUC-Tme-127216	Tuber melanosporum	26.23	3.00e-23	104.00
IUUC-Tbe-127248	Tupaia belangeri	38.44	2.00e-51	198.00
IUUC-Ttr-128429	Tursiops truncatus	33.49	4.00e-21	97.40
IUUC-Uma-129594	Ustilago maydis	29.44	5.00e-23	103.00
IUUC-Vda-129831	Verticillium dahliae	28.93	5.00e-11	63.50
IUUC-Vpa-130750	Vicugna pacos	39.60	6.00e-54	206.00
IUUC-Xtr-132676	Xenopus tropicalis	74.25	0.00e+00	848.00
IUUC-Xma-133871	Xiphophorus maculatus	35.96	5.00e-53	203.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence