iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073936

UUCD1 version

UUC-OrC-00370

Ensembl Protein ID

ENSOCUP00000008905.2

UniProt Accession

G1SZ32; G1SZ32_RABIT

Protein Name

Uncharacterized protein

Gene Name

TRIM65

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010329.2	ENSOCUT00000010338.2	ENSOCUP00000008905.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.50e-09	37.8	8	65
E3 activity/RING/RING	1.20e-07	32.2	12	51

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpltee.dlvPnlt 60
           e + C+I l l rdPv+lp+G+ + +++I+ w  + +k+cP +r+p+ ++ +l  n t
   Q: 8    EKLTCAICLVLYRDPVTLPCGHNFCKRCIQDWWHRREKKCPECREPFPDRaELRRNVT 65
           5789*******************************************55404466655 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl  ++d p++lpCgH f++ C+q w       ++e +CP Cr
   Q: 12   CAICLVLYRD-PVTLPCGHNFCKRCIQDW-----WHRREKKCPECR 51
           ********99.9**************999.....79999******8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAAQLLEEKL TCAICLVLYR DPVTLPCGHN FCKRCIQDWW HRREKKCPEC REPFPDRAEL 60
RRNVTLSGVL EALRSAPDLA LAPEAGAEPG APCKRSKEPT QFSLACTLFH WSVGPRVHEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGC AGTTGCTGGA GGAAAAGCTG ACCTGCGCCA TCTGCCTGGT GCTCTACAGG 60
GACCCGGTGA CGCTGCCCTG CGGCCACAAC TTCTGCAAGC GCTGCATCCA GGACTGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR003613--Ubox_domain
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00449--SPRY
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002422	Ailuropoda melanoleuca	69.81	2.00e-125	442.00
IUUC-Apl-003984	Anas platyrhynchos	52.50	7.00e-18	82.40
IUUC-Ago-007781	Ashbya gossypii	30.64	4.00e-09	55.80
IUUC-Ang-009514	Aspergillus niger	34.72	6.00e-08	52.00
IUUC-Bta-012830	Bos taurus	64.56	6.00e-161	560.00
IUUC-Cja-019398	Callithrix jacchus	76.80	1.00e-101	362.00
IUUC-Cfa-021033	Canis familiaris	69.45	2.00e-126	445.00
IUUC-Cpo-021359	Cavia porcellus	60.71	2.00e-150	525.00
IUUC-Csa-023706	Chlorocebus sabaeus	65.15	8.00e-169	586.00
IUUC-Dor-030830	Dipodomys ordii	65.47	2.00e-117	416.00
IUUC-Eca-033217	Equus caballus	72.22	7.00e-125	440.00
IUUC-Fca-036403	Felis catus	63.28	2.00e-163	568.00
IUUC-Fal-037118	Ficedula albicollis	35.65	1.00e-66	246.00
IUUC-Gmo-039107	Gadus morhua	30.34	3.00e-41	162.00
IUUC-Ggo-044481	Gorilla gorilla	67.43	2.00e-178	618.00
IUUC-Hsa-046113	Homo sapiens	67.05	3.00e-174	604.00
IUUC-Itr-049000	Ictidomys tridecemlineatus	63.09	1.00e-150	526.00
IUUC-Loc-052279	Lepisosteus oculatus	28.05	1.00e-41	164.00
IUUC-Laf-054143	Loxodonta africana	70.35	3.00e-126	445.00
IUUC-Mcc-055216	Macaca mulatta	64.20	8.00e-164	570.00
IUUC-Meu-056384	Macropus eugenii	58.85	4.00e-63	235.00
IUUC-Mmr-061758	Microcebus murinus	67.06	3.00e-153	534.00
IUUC-Mdo-062422	Monodelphis domestica	37.25	5.00e-56	211.00
IUUC-Mmu-063753	Mus musculus	56.29	1.00e-136	479.00
IUUC-Mpu-065880	Mustela putorius furo	61.90	1.00e-147	516.00
IUUC-Mlu-067629	Myotis lucifugus	54.91	1.00e-66	246.00
IUUC-Nle-069604	Nomascus leucogenys	69.92	2.00e-125	442.00
IUUC-Opr-070884	Ochotona princeps	61.61	1.00e-157	549.00
IUUC-Ont-072089	Oreochromis niloticus	29.57	5.00e-39	155.00
IUUC-Oan-073697	Ornithorhynchus anatinus	53.98	8.00e-43	166.00
IUUC-Oga-087916	Otolemur garnettii	61.15	8.00e-122	430.00
IUUC-Oar-090188	Ovis aries	70.61	2.00e-117	416.00
IUUC-Ptr-091364	Pan troglodytes	74.64	1.00e-134	472.00
IUUC-Pan-092240	Papio anubis	65.70	1.00e-171	595.00
IUUC-Psi-093439	Pelodiscus sinensis	46.70	2.00e-44	172.00
IUUC-Pfo-097460	Poecilia formosa	30.06	2.00e-43	169.00
IUUC-Pab-098661	Pongo abelii	59.70	3.00e-145	508.00
IUUC-Pva-102208	Pteropus vampyrus	62.71	3.00e-161	561.00
IUUC-Rno-105456	Rattus norvegicus	55.68	2.00e-132	465.00
IUUC-Sha-107040	Sarcophilus harrisii	43.77	1.00e-100	360.00
IUUC-Sar-113700	Sorex araneus	68.36	4.00e-63	235.00
IUUC-Ssc-115895	Sus scrofa	60.11	2.00e-151	528.00
IUUC-Tni-120643	Tetraodon nigroviridis	28.26	7.00e-39	154.00
IUUC-Tbe-127865	Tupaia belangeri	54.12	6.00e-61	227.00
IUUC-Ttr-128578	Tursiops truncatus	61.78	6.00e-155	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence