iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045438

Ensembl Protein ID

ENSGGOP00000025400.1

UniProt Accession

G3SBC4; G3SBC4_GORGO

Protein Name

Sorting nexin

Gene Name

SNX9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000003616.2	ENSGGOT00000003634.2	ENSGGOP00000003554.2
ENSGGOG00000003616.2	ENSGGOT00000023707.1	ENSGGOP00000025400.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.50e-10	40.6	2	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaq.nddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v+yd+ a+  ++eLt ++G+++++  + +  +gWl+g ++ +g rGl+P ++ve l
   Q: 2    RVMYDFAAEpGNNELTVNEGEIITIT-NPDVGGGWLEG-RNIKGERGLVPTDYVEIL 56
           689*****85689************8.99*********.5**************865 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

ARVMYDFAAE PGNNELTVNE GEIITITNPD VGGGWLEGRN IKGERGLVPT DYVEILPSDG 60
KDQFSCGNSV ADQAFLDSLS ASTAQASSSA ASNNHQVGSG NDPWSAWSAS KSGNWESSEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCACAG AGGTGAGGGG CGCGCGGCGC AGGCCGGGCC GGTCGCTCAG GCCCGCGGCG 60
GCGCGGAGAG GGTCGGGGCC GGGGCCGCGG GGAGGGTCGG GGCCAGGGGT GGTCGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0472--Membrane
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR001683--Phox
IPR001452--SH3_domain
IPR028644--SNX9
IPR014536--Snx9_subfam
IPR019497--Sorting_nexin_WASP-bd-dom

PROSITE

PS50195--PX
PS50002--SH3

Pfam

PF10456--BAR_3_WASP_bdg
PF00787--PX
PF00018--SH3_1

SMART

SM00312--PX
SM00326--SH3

Gene Ontology

GO:0030136--C:clathrin-coated vesicle
GO:0030659--C:cytoplasmic vesicle membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005802--C:trans-Golgi network
GO:0005545--F:1-phosphatidylinositol binding
GO:0036089--P:cleavage furrow formation
GO:0016197--P:endosomal transport
GO:0006886--P:intracellular protein transport
GO:0060988--P:lipid tube assembly
GO:0000281--P:mitotic cytokinesis
GO:0007067--P:mitotic nuclear division
GO:0097320--P:plasma membrane tubulation
GO:0043547--P:positive regulation of GTPase activity
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0045860--P:positive regulation of protein kinase activity
GO:0032461--P:positive regulation of protein oligomerization
GO:0006898--P:receptor-mediated endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001493	Ailuropoda melanoleuca	89.70	0.00e+00	1032.00
IUUC-Apl-003889	Anas platyrhynchos	80.17	0.00e+00	921.00
IUUC-Ame-011163	Astyanax mexicanus	59.81	0.00e+00	697.00
IUUC-Bta-013027	Bos taurus	89.00	0.00e+00	1027.00
IUUC-Cel-018605	Caenorhabditis elegans	31.82	7.00e-54	204.00
IUUC-Cja-019428	Callithrix jacchus	94.08	0.00e+00	1101.00
IUUC-Cfa-021208	Canis familiaris	89.86	0.00e+00	1031.00
IUUC-Cpo-021353	Cavia porcellus	88.68	0.00e+00	1025.00
IUUC-Cho-025020	Choloepus hoffmanni	85.93	9.00e-135	473.00
IUUC-Cin-025695	Ciona intestinalis	31.93	5.00e-87	315.00
IUUC-Csv-025870	Ciona savignyi	32.61	8.00e-82	297.00
IUUC-Dre-027983	Danio rerio	59.62	0.00e+00	692.00
IUUC-Dme-031845	Drosophila melanogaster	36.39	1.00e-63	237.00
IUUC-Fca-036506	Felis catus	89.38	0.00e+00	1013.00
IUUC-Fal-037443	Ficedula albicollis	73.19	0.00e+00	882.00
IUUC-Gmo-039464	Gadus morhua	54.31	8.00e-171	593.00
IUUC-Gac-041835	Gasterosteus aculeatus	55.19	5.00e-174	604.00
IUUC-Hsa-046762	Homo sapiens	95.77	0.00e+00	1117.00
IUUC-Itr-048294	Ictidomys tridecemlineatus	88.68	0.00e+00	1024.00
IUUC-Lch-049906	Latimeria chalumnae	64.78	5.00e-154	537.00
IUUC-Loc-052748	Lepisosteus oculatus	63.33	0.00e+00	706.00
IUUC-Lma-053062	Leptosphaeria maculans	43.86	2.00e-05	43.90
IUUC-Laf-053373	Loxodonta africana	88.85	0.00e+00	1026.00
IUUC-Mcc-054953	Macaca mulatta	94.75	0.00e+00	1075.00
IUUC-Mga-059536	Meleagris gallopavo	76.76	0.00e+00	917.00
IUUC-Mmr-061000	Microcebus murinus	90.76	0.00e+00	1048.00
IUUC-Mdo-061885	Monodelphis domestica	84.18	0.00e+00	976.00
IUUC-Mmu-063532	Mus musculus	86.82	0.00e+00	1015.00
IUUC-Mlu-067143	Myotis lucifugus	86.91	0.00e+00	1004.00
IUUC-Ont-072028	Oreochromis niloticus	61.93	0.00e+00	724.00
IUUC-Oan-073741	Ornithorhynchus anatinus	75.00	6.00e-55	206.00
IUUC-Ola-086919	Oryzias latipes	60.00	0.00e+00	712.00
IUUC-Oga-088465	Otolemur garnettii	89.36	0.00e+00	1002.00
IUUC-Oar-089562	Ovis aries	88.49	0.00e+00	1024.00
IUUC-Ptr-090632	Pan troglodytes	95.77	0.00e+00	1117.00
IUUC-Pan-092192	Papio anubis	94.75	0.00e+00	1071.00
IUUC-Psi-093346	Pelodiscus sinensis	79.73	0.00e+00	936.00
IUUC-Pma-094619	Petromyzon marinus	34.83	5.00e-65	241.00
IUUC-Pno-094868	Phaeosphaeria nodorum	43.86	2.00e-05	43.90
IUUC-Pfo-096634	Poecilia formosa	61.85	0.00e+00	716.00
IUUC-Pab-097866	Pongo abelii	95.43	0.00e+00	1113.00
IUUC-Pva-102273	Pteropus vampyrus	87.84	0.00e+00	991.00
IUUC-Pte-104168	Pyrenophora teres	43.86	3.00e-05	43.10
IUUC-Rno-105513	Rattus norvegicus	83.08	0.00e+00	966.00
IUUC-Ssc-116184	Sus scrofa	90.20	0.00e+00	1033.00
IUUC-Tgu-117370	Taeniopygia guttata	79.67	0.00e+00	942.00
IUUC-Tru-117764	Takifugu rubripes	58.55	0.00e+00	681.00
IUUC-Tni-119947	Tetraodon nigroviridis	62.79	0.00e+00	728.00
IUUC-Ttr-128700	Tursiops truncatus	85.98	0.00e+00	971.00
IUUC-Xtr-132466	Xenopus tropicalis	66.00	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence