iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033361

UUCD1 version

UUC-EqC-01033

Ensembl Protein ID

ENSECAP00000017638.1

UniProt Accession

F7BTM1; F7BTM1_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019869.1	ENSECAT00000021418.1	ENSECAP00000017638.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-98	330.5	269	598

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l+++  ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 269  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLSHS--SNAHTALMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 355
           9*****************************7788888877..6899***************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+  l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 356  QQDAQEFLRFLLDGLHNEVNRVTVRPKSNPENLDH--LPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 442
           *******************9955555554444443..2222335559****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 443  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 528
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 529  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpVTGEWHTFNDSSVTPMSSSQVRT---SDAYLLFYE 598
           ******9553....78*************************44666*******************...********8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDA PYAKSGYGTY TPSSYGANLA ASFLEKEKLG FKPGPPTSLL 60
TRPRTYGPSS ILDYDRSRPL LRPDIIGGGK RPESQTWGTE RPSGSGLSGG SGFPYGVTNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGGCAGG AGCCGAGGCC AGGGAGCCCT TTGCGTCAGC TGCTGCTCAC TGCACAGCGC 60
CAGTACCGGC CGGGACTCAC TCGCAGCTCC ATGCTTGTGC CCGGCTCGAC TCGTCCATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	96.37	0.00e+00	1116.00
IUUC-Aca-005132	Anolis carolinensis	60.06	0.00e+00	675.00
IUUC-Ame-011102	Astyanax mexicanus	75.50	4.00e-145	507.00
IUUC-Bta-012529	Bos taurus	93.56	0.00e+00	1026.00
IUUC-Cja-019016	Callithrix jacchus	91.15	0.00e+00	1036.00
IUUC-Cfa-020714	Canis familiaris	96.20	0.00e+00	1124.00
IUUC-Cpo-021727	Cavia porcellus	90.59	0.00e+00	1041.00
IUUC-Csa-023071	Chlorocebus sabaeus	98.85	0.00e+00	687.00
IUUC-Cin-025797	Ciona intestinalis	50.43	4.00e-95	341.00
IUUC-Csv-026132	Ciona savignyi	50.43	1.00e-97	350.00
IUUC-Dre-027872	Danio rerio	81.82	3.00e-163	567.00
IUUC-Dno-029329	Dasypus novemcinctus	93.73	0.00e+00	1080.00
IUUC-Dor-030574	Dipodomys ordii	93.40	0.00e+00	1039.00
IUUC-Dme-032208	Drosophila melanogaster	47.63	1.00e-82	301.00
IUUC-Ete-032725	Echinops telfairi	84.50	0.00e+00	631.00
IUUC-Eeu-035272	Erinaceus europaeus	79.72	0.00e+00	718.00
IUUC-Fca-036497	Felis catus	96.70	0.00e+00	1125.00
IUUC-Fal-036766	Ficedula albicollis	64.27	0.00e+00	675.00
IUUC-Gmo-039129	Gadus morhua	67.08	1.00e-123	436.00
IUUC-Gga-040889	Gallus gallus	84.16	4.00e-148	517.00
IUUC-Gac-042475	Gasterosteus aculeatus	70.40	2.00e-137	482.00
IUUC-Ggo-044814	Gorilla gorilla	92.82	7.00e-178	616.00
IUUC-Hsa-045937	Homo sapiens	93.40	0.00e+00	1050.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	94.61	0.00e+00	1103.00
IUUC-Lch-050527	Latimeria chalumnae	60.99	0.00e+00	631.00
IUUC-Loc-052697	Lepisosteus oculatus	79.43	4.00e-162	564.00
IUUC-Laf-054167	Loxodonta africana	88.18	0.00e+00	1030.00
IUUC-Mcc-055584	Macaca mulatta	94.22	0.00e+00	1093.00
IUUC-Meu-056542	Macropus eugenii	86.82	0.00e+00	957.00
IUUC-Mga-060020	Meleagris gallopavo	60.13	0.00e+00	639.00
IUUC-Mmr-060989	Microcebus murinus	95.38	0.00e+00	1108.00
IUUC-Mdo-062761	Monodelphis domestica	86.33	0.00e+00	956.00
IUUC-Mmu-063710	Mus musculus	91.11	0.00e+00	1065.00
IUUC-Mpu-066573	Mustela putorius furo	96.86	0.00e+00	1125.00
IUUC-Nle-070013	Nomascus leucogenys	93.41	0.00e+00	1026.00
IUUC-Opr-070907	Ochotona princeps	92.09	0.00e+00	1026.00
IUUC-Ont-071944	Oreochromis niloticus	82.13	5.00e-165	573.00
IUUC-Oan-073105	Ornithorhynchus anatinus	83.02	1.00e-146	512.00
IUUC-Ocu-073941	Oryctolagus cuniculus	93.90	0.00e+00	1077.00
IUUC-Ola-087412	Oryzias latipes	78.06	2.00e-151	529.00
IUUC-Oga-088973	Otolemur garnettii	95.38	0.00e+00	1109.00
IUUC-Oar-089916	Ovis aries	94.22	0.00e+00	1075.00
IUUC-Ptr-090998	Pan troglodytes	93.73	0.00e+00	1057.00
IUUC-Pan-092686	Papio anubis	94.39	0.00e+00	1095.00
IUUC-Psi-093284	Pelodiscus sinensis	72.01	9.00e-125	439.00
IUUC-Pma-094462	Petromyzon marinus	64.71	5.00e-74	270.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.11	1.00e-39	158.00
IUUC-Pfo-097352	Poecilia formosa	80.00	3.00e-167	581.00
IUUC-Pab-098688	Pongo abelii	87.46	0.00e+00	949.00
IUUC-Pca-100205	Procavia capensis	94.52	0.00e+00	647.00
IUUC-Pva-103188	Pteropus vampyrus	95.54	0.00e+00	1076.00
IUUC-Rno-105853	Rattus norvegicus	92.07	0.00e+00	1086.00
IUUC-Sha-107237	Sarcophilus harrisii	86.82	0.00e+00	953.00
IUUC-Sar-113103	Sorex araneus	91.64	0.00e+00	629.00
IUUC-Ssc-115955	Sus scrofa	95.71	0.00e+00	1084.00
IUUC-Tgu-116894	Taeniopygia guttata	70.34	0.00e+00	630.00
IUUC-Tru-117703	Takifugu rubripes	66.37	7.00e-134	469.00
IUUC-Tsy-118879	Tarsius syrichta	96.41	0.00e+00	838.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.93	1.00e-153	535.00
IUUC-Tbe-127367	Tupaia belangeri	87.50	0.00e+00	689.00
IUUC-Ttr-128773	Tursiops truncatus	92.08	0.00e+00	1064.00
IUUC-Vpa-130402	Vicugna pacos	85.85	0.00e+00	810.00
IUUC-Xtr-132658	Xenopus tropicalis	57.53	1.00e-180	625.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence